LATS2 抗体 (AA 228-258)
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北京 101111
Quick Overview for LATS2 抗体 (AA 228-258) (ABIN391034)
抗原
See all LATS2 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 228-258
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纯化方法
- This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
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免疫原
- This LATS2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 228-258 amino acids from the Central region of human LATS2.
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亚型
- Ig Fraction
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应用备注
- IHC-P: 1:10~50
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
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有效期
- 6 months
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: "MicroRNA-372 is associated with poor prognosis in colorectal cancer." in: Oncology, Vol. 82, Issue 4, pp. 205-12, (2012) (PubMed).
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: "MicroRNA-372 is associated with poor prognosis in colorectal cancer." in: Oncology, Vol. 82, Issue 4, pp. 205-12, (2012) (PubMed).
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- LATS2 (LATS, Large Tumor Suppressor, Homolog 2 (Drosophila) (LATS2))
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别名
- LATS2
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背景
- LATS2 is a serine/threonine protein kinase belonging to the LATS tumor suppressor family. This protein localizes to centrosomes during interphase, and early and late metaphase. It interacts with the centrosomal proteins aurora-A and ajuba and is required for accumulation of gamma-tubulin and spindle formation at the onset of mitosis. It also interacts with a negative regulator of p53 and may function in a positive feedback loop with p53 that responds to cytoskeleton damage. Additionally, it can function as a co-repressor of androgen-responsive gene expression.
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分子量
- 120136
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基因ID
- 26524
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NCBI登录号
- NP_055387
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UniProt
- Q9NRM7
抗原
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