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LATS2 抗体

(LATS, Large Tumor Suppressor, Homolog 2 (Drosophila) (LATS2))
This gene encodes a serine/threonine protein kinase belonging to the LATS tumor suppressor family. The protein localizes to centrosomes during interphase, and early and late metaphase. It interacts with the centrosomal proteins aurora-A and ajuba and is required for accumulation of gamma-tubulin and spindle formation at the onset of mitosis. It also interacts with a negative regulator of p53 and may function in a positive feedback loop with p53 that responds to cytoskeleton damage. Additionally, it can function as a co-repressor of androgen-responsive gene expression.
LATS2 抗体  (AA 1-100) LATS2 抗体  (AA 1-100) LATS2 抗体 (AA 1-100) (ABIN7268192)

LATS2 适用: 人 IHC, WB 宿主: 兔 Polyclonal unconjugated

LATS2 抗体  (pSer83) LATS2 抗体  (pSer83) LATS2 抗体 (pSer83) (ABIN753568)

LATS2 适用: 人, 小鼠, 大鼠 ELISA, IF (cc), IF (p), IHC (fro), IHC (p), WB 宿主: 兔 Polyclonal unconjugated

LATS2 抗体  (AA 228-258) LATS2 抗体  (AA 228-258) LATS2 抗体 (AA 228-258) (ABIN3031595)

LATS2 适用: 人, 小鼠 IHC, ELISA, WB 宿主: 兔 Polyclonal unconjugated

LATS2 抗体 by 适用

Find LATS2 抗体 for a variety of species such as anti-Mouse LATS2, anti-Human LATS2, anti-Rat LATS2. The species listed below are among those available. Click on a link to go to the corresponding products.

LATS2 抗体 by 应用范围

Find LATS2 抗体 validated for a specific application such as WB, ELISA, IHC, IHC (p). Some of the available applications are listed below. Click on a link to go to the corresponding products.

LATS2 抗体 by 抗体来源

Find LATS2 抗体 with a specific 抗体来源. The 抗体来源 listed below are among those available. Click on a link to go to the corresponding products.

LATS2 抗体 by 抗原表位

Find LATS2 抗体 with a specific epitope. The epitopes listed below are among those available. Click on a link to go to the corresponding products.

LATS2 抗体 by 克隆形成能力

Find available monoclonal or polyclonal LATS2 抗体. Click on a link to go to the corresponding products.

LATS2 抗体 by 克隆

Find LATS2 抗体 with a specific 克隆. The 克隆 listed below are among those available. Click on a link to go to the corresponding products.

LATS2 抗体 by 标记

Find LATS2 抗体 with a specific conjugate such as Biotin, Alexa Fluor 488, Alexa Fluor 555. The conjugates listed below are among those available. Click on a link to go to the corresponding products.

Popular LATS2 抗体

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application ELISA, IHC
Validations
  • (2)
Cat. No. ABIN7191263
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Mouse
Application ELISA, IHC
Validations
  • (2)
Cat. No. ABIN7242491
Quantity 200 μL
Datasheet Datasheet
Reactivity Human, Mouse
Application IF, IHC, ELISA
Validations
  • (2)
Cat. No. ABIN1534144
Quantity 100 μg
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application ELISA, IHC, WB
Validations
  • (2)
Cat. No. ABIN6262923
Quantity 100 μL
Datasheet Datasheet
Reactivity Mouse
Application ELISA, WB
Validations
  • (2)
Cat. No. ABIN3031594
Quantity 0.4 mL
Datasheet Datasheet
Reactivity Human, Mouse
Application IHC (p), WB
Validations
  • (2)
Cat. No. ABIN5536845
Quantity 400 μL
Datasheet Datasheet
Reactivity Human, Mouse
Application IHC, WB
Validations
  • (2)
Cat. No. ABIN2489432
Quantity 400 μL
Datasheet Datasheet
Reactivity Human
Application ELISA, WB
Validations
  • (3)
  • (1)
Cat. No. ABIN531847
Quantity 100 μg
Datasheet Datasheet
Reactivity Zebrafish (Danio rerio)
Application ELISA, WB
Validations
  • (1)
Cat. No. ABIN7179774
Quantity 100 μg
Datasheet Datasheet
Reactivity Mouse
Application IHC (p), WB
Validations
  • (4)
Cat. No. ABIN1881491
Quantity 400 μL
Datasheet Datasheet
Reactivity Human
Application IHC (p)
Validations
  • (1)
Cat. No. ABIN391034
Quantity 400 μL
Datasheet Datasheet
Reactivity Human
Application ELISA, IF, IHC
Validations
Cat. No. ABIN7187149
Quantity 100 μg
Datasheet Datasheet
Reactivity Human, Mouse
Application ELISA, IF, IHC (p)
Validations
Cat. No. ABIN6287301
Quantity 50 μL
Datasheet Datasheet
Reactivity Zebrafish (Danio rerio)
Application ELISA
Validations
Cat. No. ABIN7179775
Quantity 100 μg
Datasheet Datasheet
Reactivity Zebrafish (Danio rerio)
Application
Validations
Cat. No. ABIN7179776
Quantity 100 μg
Datasheet Datasheet

Latest Publications for our LATS2 抗体

Wigerius, Quinn, Diab, Clattenburg, Kolar, Qi, Krueger, Fawcett: "The polarity protein Angiomotin p130 controls dendritic spine maturation." in: The Journal of cell biology, Vol. 217, Issue 2, pp. 715-730, (2018) (PubMed).

Zhang, Wang, Xie, Chen, Sinkemani, Yu, Wang, Mao, Wu: "Dysregulation of YAP by the Hippo pathway is involved in intervertebral disc degeneration, cell contact inhibition, and cell senescence." in: Oncotarget, Vol. 9, Issue 2, pp. 2175-2192, (2018) (PubMed).

Wang, Sinnett-Smith, Stevens, Young, Rozengurt et al.: "Biphasic Regulation of Yes-associated Protein (YAP) Cellular Localization, Phosphorylation, and Activity by G Protein-coupled Receptor Agonists in Intestinal Epithelial Cells: A NOVEL ROLE FOR ..." in: The Journal of biological chemistry, Vol. 291, Issue 34, pp. 17988-8005, (2016) (PubMed).

Tanaka, Osada, Fujii, Fukatsu, Hida, Horio, Kondo, Sato, Hasegawa, Tsujimura, Sekido: "LIM-domain protein AJUBA suppresses malignant mesothelioma cell proliferation via Hippo signaling cascade." in: Oncogene, Vol. 34, Issue 1, pp. 73-83, (2015) (PubMed).

Staedel, Varon, Nguyen, Vialet, Chambonnier, Rousseau, Soubeyran, Evrard, Couillaud, Darfeuille: "Inhibition of Gastric Tumor Cell Growth Using Seed-targeting LNA as Specific, Long-lasting MicroRNA Inhibitors." in: Molecular therapy. Nucleic acids, Vol. 4, pp. e246, (2015) (PubMed).

Xiang, Gilkes, Hu, Takano, Luo, Lu, Bullen, Samanta, Liang, Semenza: "Hypoxia-inducible factor 1 mediates TAZ expression and nuclear localization to induce the breast cancer stem cell phenotype." in: Oncotarget, Vol. 5, Issue 24, pp. 12509-27, (2015) (PubMed).

Pefani, Latusek, Pires, Grawenda, Yee, Hamilton, van der Weyden, Esashi, Hammond, ONeill: "RASSF1A-LATS1 signalling stabilizes replication forks by restricting CDK2-mediated phosphorylation of BRCA2." in: Nature cell biology, Vol. 16, Issue 10, pp. 962-71, 1-8, (2014) (PubMed).

Reuven, Adler, Meltser, Shaul: "The Hippo pathway kinase Lats2 prevents DNA damage-induced apoptosis through inhibition of the tyrosine kinase c-Abl." in: Cell death and differentiation, Vol. 20, Issue 10, pp. 1330-40, (2013) (PubMed).

Zhang, Iyer, Chowdhury, Ji, Xiao, Yang, Chen, Tsai, Dong: "KIBRA regulates aurora kinase activity and is required for precise chromosome alignment during mitosis." in: The Journal of biological chemistry, Vol. 287, Issue 41, pp. 34069-77, (2012) (PubMed).

Zhang, Rodriguez-Aznar, Yabuta, Owen, Mingot, Nojima, Nieto, Longmore: "Lats2 kinase potentiates Snail1 activity by promoting nuclear retention upon phosphorylation." in: The EMBO journal, Vol. 31, Issue 1, pp. 29-43, (2012) (PubMed).

Aliases for LATS2 抗体

large tumor suppressor kinase 2 (LATS2) 抗体
large tumor suppressor 2 (Lats2) 抗体
large tumor suppressor kinase 2 (Lats2) 抗体
large tumor suppressor kinase 2 (lats2) 抗体
4932411G09Rik 抗体
AV277261 抗体
AW228608 抗体
KPM 抗体
lats2 抗体
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