HRAS 抗体 (AA 146-176)
Quick Overview for HRAS 抗体 (AA 146-176) (ABIN3031138)
抗原
See all HRAS 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- AA 146-176
-
交叉反应 （详细）
- Expected species reactivity: Rat, Chicken
-
纯化方法
- Purified
-
免疫原
- A portion of amino acids 146-176 from the human protein was used as the immunogen for this H-RAS antibody.
-
亚型
- Ig Fraction
-
-
anti-HRas proto-oncogene, GTPase (HRAS) (C-Term) antibody
HRAS 适用: 人, 小鼠, 大鼠 WB, IF, IHC (p), ICC 宿主: 兔 Polyclonal unconjugated
anti-HRas proto-oncogene, GTPase (HRAS) antibodyHRAS 适用: 人, 小鼠, 大鼠, 犬, 猴 WB, IHC, IF, IHC (p) 宿主: 小鼠 Monoclonal 1C2 unconjugated
anti-HRas proto-oncogene, GTPase (HRAS) (AA 104-128) antibodyHRAS 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-HRas proto-oncogene, GTPase (HRAS) antibodyHRAS 适用: 人, 小鼠, 大鼠, 犬, 猴 WB, IHC, IF, IHC (p) 宿主: 小鼠 Monoclonal 1A1 unconjugated
anti-HRas proto-oncogene, GTPase (HRAS) (AA 104-128) antibodyHRAS 适用: 人 WB, IF, IHC (p) 宿主: 兔 Polyclonal RB15622 unconjugated
anti-HRas proto-oncogene, GTPase (HRAS) (AA 2-186) antibodyHRAS 适用: 大鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-HRas proto-oncogene, GTPase (HRAS) (AA 12-181) antibodyHRAS 适用: 人 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-HRas proto-oncogene, GTPase (HRAS) antibodyHRAS 适用: 人, 小鼠, 大鼠 WB, ELISA 宿主: 小鼠 Monoclonal H-Ras-03 unconjugated
anti-HRas proto-oncogene, GTPase (HRAS) (AA 1-189) antibodyHRAS 适用: 人 WB, PLA 宿主: 小鼠 Polyclonal unconjugated
anti-HRas proto-oncogene, GTPase (HRAS) antibodyHRAS 适用: 人 WB 宿主: 小鼠 Monoclonal H-RAS-03 unconjugated
-
-
应用备注
- Titration of the H-RAS antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000,Immunofluorescence: 1:10-1:50
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
缓冲液
- In 1X PBS, pH 7.4, with 0.09 % sodium azide
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
储存条件
- -20 °C
-
储存方法
- Aliquot the H-RAS antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
-
-
- HRAS (HRas proto-oncogene, GTPase (HRAS))
-
别名
- H-RAS
-
背景
- This gene belongs to the Ras oncogene family, whose members are related to the transforming genes of mammalian sarcoma retroviruses. The products encoded by these genes function in signal transduction pathways. These proteins can bind GTP and GDP, and they have intrinsic GTPase activity. This protein undergoes a continuous cycle of de- and re-palmitoylation, which regulates its rapid exchange between the plasma membrane and the Golgi apparatus. Mutations in this gene cause Costello syndrome, a disease characterized by increased growth at the prenatal stage, growth deficiency at the postnatal stage, predisposition to tumor formation, mental retardation, skin and musculoskeletal abnormalities, distinctive facial appearance and cardiovascular abnormalities. Defects in this gene are implicated in a variety of cancers, including bladder cancer, follicular thyroid cancer, and oral squamous cell carcinoma. Multiple transcript variants, which encode different isoforms, have been identified for this gene.
-
UniProt
- P01112
-
途径
- p53 Pathway, MAPK Pathway, RTK signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Hepatitis C, Autophagy, Signaling Events mediated by VEGFR1 and VEGFR2, Signaling of Hepatocyte Growth Factor Receptor, Regulation of long-term Neuronal Synaptic Plasticity, VEGF Signaling, BCR Signaling
抗原
-
