CHEK1 抗体 (AA 258-287)
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Quick Overview for CHEK1 抗体 (AA 258-287) (ABIN3030468)
抗原
See all CHEK1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 258-287
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纯化方法
- Antigen affinity purified
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免疫原
- A portion of amino acids 258-287 from the human protein was used as the immunogen for this CHK1 antibody.
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亚型
- Ig Fraction
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应用备注
- The stated application concentrations are suggested starting amounts. Titration of the CHK1 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- In 1X PBS, pH 7.4, with 0.09 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at 4°C for up to one month. For long term, aliquot the CHK1 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
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- CHEK1 (Checkpoint Kinase 1 (CHEK1))
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别名
- CHK1
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背景
- Checkpoint kinase 1, commonly referred to as CHK1 is an serine/threonine-specific protein kinase that in humans, is encoded by the CHEK1 gene. CHK1 coordinates the DNA damage response (DDR) and cell cycle checkpoint response. Activation results in the initiation of cell cycle checkpoints, cell cycle arrest, DNA repair and cell death to prevent damaged cells from progressing through the cell cycle.
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UniProt
- O14757
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途径
- p53 Pathway, Apoptosis, Cell Division Cycle, DNA Damage Repair
抗原
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