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ACVR2B 抗体 (C-Term)

ACVR2B 适用: 人, 大鼠 WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN4886423
发货至: 中国
  • 抗原 See all ACVR2B 抗体
    ACVR2B (Activin A Receptor, Type IIB (ACVR2B))
    抗原表位
    • 15
    • 9
    • 7
    • 7
    • 7
    • 6
    • 6
    • 5
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 431-466, C-Term
    适用
    • 72
    • 31
    • 30
    • 11
    • 10
    • 7
    • 6
    • 6
    • 6
    • 5
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    人, 大鼠
    宿主
    • 70
    • 7
    • 3
    克隆类型
    • 75
    • 5
    多克隆
    标记
    • 37
    • 12
    • 5
    • 4
    • 4
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This ACVR2B antibody is un-conjugated
    应用范围
    • 75
    • 28
    • 23
    • 13
    • 13
    • 8
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB)
    原理
    Rabbit IgG polyclonal antibody for Activin receptor type-2B(ACVR2B) detection. Tested with WB in Human,Rat.
    序列
    VVHKKMRPTI KDHWLKHPGL AQLCVTIEEC WDHDAE
    交叉反应 (详细)
    No cross reactivity with other proteins.
    产品特性
    Rabbit IgG polyclonal antibody for Activin receptor type-2B(ACVR2B) detection. Tested with WB in Human,Rat.
    Gene Name: activin A receptor type 2B
    Protein Name: Activin receptor type-2B
    纯化方法
    Immunogen affinity purified.
    免疫原
    A synthetic peptide corresponding to a sequence at the C-terminus of human ACVR2B (431-466aa VVHKKMRPTIKDHWLKHPGLAQLCVTIEECWDHDAE), identical to the related mouse and rat sequences.
    亚型
    IgG
    Top Product
    Discover our top product ACVR2B Primary Antibody
  • 应用备注
    WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human, Rat
    Notes: Tested Species: Species with positive results.
    Other applications have not been tested. Optimal dilutions should be determined by end users.
    说明

    Antibody can be supported by chemiluminescence kit ABIN921124 in WB.

    限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
    浓度
    500 μg/mL
    缓冲液
    Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    4 °C/-20 °C
    储存方法
    At -20°C for one year. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.
  • 抗原
    ACVR2B (Activin A Receptor, Type IIB (ACVR2B))
    别名
    ACVR2B (ACVR2B 产品)
    别名
    ACVR2B antibody, XAR1 antibody, actr-iib antibody, actriib antibody, ACTRIIB antibody, ActR-IIB antibody, HTX4 antibody, ActRIIB antibody, actr2b antibody, actrIIb antibody, wu:fj97d11 antibody, activin A receptor type 2B antibody, activin A receptor type 2B L homeolog antibody, activin A receptor type 2Ba antibody, activin receptor IIB antibody, ACVR2B antibody, acvr2b antibody, acvr2b.L antibody, Acvr2b antibody, acvr2ba antibody
    背景
    Activin receptor type-2B is a protein that in humans is encoded by the ACVR2B gene. Activins are dimeric growth and differentiation factors which belong to the transforming growth factor-beta (TGF-beta) superfamily of structurally related signaling proteins. Activins signal through a heteromeric complex of receptor serine kinases which include at least two type I (I and IB) and two type II (II and IIB) receptors. These receptors are all transmembrane proteins, composed of a ligand-binding extracellular domain with cysteine-rich region, a transmembrane domain, and a cytoplasmic domain with predicted serine/threonine specificity. Type I receptors are essential for signaling, and type II receptors are required for binding ligands and for expression of type I receptors. Type I and II receptors form a stable complex after ligand binding, resulting in phosphorylation of type I receptors by type II receptors. Type II receptors are considered to be constitutively active kinases. This ACVR2B gene encodes activin A type IIB receptor, which displays a 3- to 4-fold higher affinity for the ligand than activin A type II receptor.

    Synonyms: ActRIIB | ActR-IIB | ActR IIB | ACVR2B | ACVR-2B | ACVR 2B | HTX4 | MGC116908 | Q13705
    基因ID
    93
    UniProt
    Q13705
    途径
    Hormone Transport, Cancer Immune Checkpoints
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