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TNFRSF10A 抗体 (Extracellular Domain) (PE)

TNFRSF10A 适用: 人 FACS 宿主: 小鼠 Monoclonal DR-4-02 PE
产品编号 ABIN488159
发货至: 中国
  • 抗原 See all TNFRSF10A 抗体
    TNFRSF10A (Tumor Necrosis Factor Receptor Superfamily, Member 10a (TNFRSF10A))
    抗原表位
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    Extracellular Domain
    适用
    • 80
    • 5
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    宿主
    • 44
    • 36
    小鼠
    克隆类型
    • 46
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    单克隆
    标记
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    This TNFRSF10A antibody is conjugated to PE
    应用范围
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    Flow Cytometry (FACS)
    特异性
    The antibody DR-4-02 recognizes TRAIL-R1 (DR4), a Human Death Receptor 4 (468 amino acids) expressed in most Human tissues (spleen, peripheral blood leucocytes, thymus) and in a variety of tumour-derived cell lines.
    交叉反应 (详细)
    Species reactivity (tested):Human.
    产品特性
    Synonyms: APO2, DR4, Death receptor 4, TRAIL receptor 1, TRAIL-R1, TNFRSF10A, Tumor necrosis factorreceptor superfamily member 10A, TNF-related apoptosis-inducing ligand receptor 1
    纯化方法
    Size-Exclusion Chromatography.
    免疫原
    Fusion protein containing the extracellular part of TRAIL-R1 and the constant part of theheavy chain of the Human IgG1.
    克隆位点
    DR-4-02
    亚型
    IgG1
    Top Product
    Discover our top product TNFRSF10A Primary Antibody
  • 应用备注
    Flow Cytometry analysis: 5 μg/mL.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    限制
    仅限研究用
  • 浓度
    0.1 mg/mL
    缓冲液
    PBS containing 15 mM sodium azide as preservative and 0.2 % (w/v) high-grade BSA (Protease free) as stabilizer.
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C
    储存方法
    Store the antibody in the dark at 2-8 °C. DO NOT FREEZE! Avoid prolonged exposure to light.
    Shelf life: one year from despatch.
    有效期
    12 months
  • 抗原
    TNFRSF10A (Tumor Necrosis Factor Receptor Superfamily, Member 10a (TNFRSF10A))
    别名
    CD261 / TRAILR1 (TNFRSF10A 产品)
    别名
    APO2 antibody, CD261 antibody, DR4 antibody, TRAILR-1 antibody, TRAILR1 antibody, TNFRSF10A antibody, TNF receptor superfamily member 10a antibody, tumor necrosis factor receptor superfamily member 26 antibody, tumor necrosis factor receptor superfamily, member 10a antibody, TNFRSF10A antibody, LOC510798 antibody
    背景
    TRAIL-R1 (CD261, DR4) is a type I transmembrane protein, also called TRAIL receptor 1. The ligand for this DR4 death receptor has been identified and termed TRAIL, which is a member of the TNF family. DR4, as many other receptors (Fas, TNFR1, etc.), mediates apoptosis and NF kappaB activation in many cells and tissues. Apoptosis, a programmed cell death, is a operating process in normal cellular differentiation and development of multicellular organisms. Apoptosis is induced by coupled of certain cytokines (TNF family - TNF, Fas ligand) and their death domain containing receptors (TNFR1, Fas receptor).Synonyms: APO2, DR4, Death receptor 4, TNF-related apoptosis-inducing ligand receptor 1, TNFRSF10A, TRAIL receptor 1, TRAIL-R1, Tumor necrosis factor receptor superfamily member 10A
    基因ID
    8797
    UniProt
    O00220
    途径
    Apoptosis, Positive Regulation of Endopeptidase Activity
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