TNFRSF10A 抗体 (Extracellular Domain) (PE)
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- 抗原 See all TNFRSF10A 抗体
- TNFRSF10A (Tumor Necrosis Factor Receptor Superfamily, Member 10a (TNFRSF10A))
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抗原表位
- Extracellular Domain
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适用
- 人
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This TNFRSF10A antibody is conjugated to PE
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应用范围
- Flow Cytometry (FACS)
- 特异性
- The antibody DR-4-02 recognizes TRAIL-R1 (DR4), a Human Death Receptor 4 (468 amino acids) expressed in most Human tissues (spleen, peripheral blood leucocytes, thymus) and in a variety of tumour-derived cell lines.
- 交叉反应 (详细)
- Species reactivity (tested):Human.
- 产品特性
- Synonyms: APO2, DR4, Death receptor 4, TRAIL receptor 1, TRAIL-R1, TNFRSF10A, Tumor necrosis factorreceptor superfamily member 10A, TNF-related apoptosis-inducing ligand receptor 1
- 纯化方法
- Size-Exclusion Chromatography.
- 免疫原
- Fusion protein containing the extracellular part of TRAIL-R1 and the constant part of theheavy chain of the Human IgG1.
- 克隆位点
- DR-4-02
- 亚型
- IgG1
- Top Product
- Discover our top product TNFRSF10A Primary Antibody
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- 应用备注
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Flow Cytometry analysis: 5 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. - 限制
- 仅限研究用
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- 浓度
- 0.1 mg/mL
- 缓冲液
- PBS containing 15 mM sodium azide as preservative and 0.2 % (w/v) high-grade BSA (Protease free) as stabilizer.
- 储存液
- Sodium azide
- 注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C
- 储存方法
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Store the antibody in the dark at 2-8 °C. DO NOT FREEZE! Avoid prolonged exposure to light.
Shelf life: one year from despatch. - 有效期
- 12 months
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- 抗原
- TNFRSF10A (Tumor Necrosis Factor Receptor Superfamily, Member 10a (TNFRSF10A))
- 别名
- CD261 / TRAILR1 (TNFRSF10A 产品)
- 别名
- APO2 antibody, CD261 antibody, DR4 antibody, TRAILR-1 antibody, TRAILR1 antibody, TNFRSF10A antibody, TNF receptor superfamily member 10a antibody, tumor necrosis factor receptor superfamily member 26 antibody, tumor necrosis factor receptor superfamily, member 10a antibody, TNFRSF10A antibody, LOC510798 antibody
- 背景
- TRAIL-R1 (CD261, DR4) is a type I transmembrane protein, also called TRAIL receptor 1. The ligand for this DR4 death receptor has been identified and termed TRAIL, which is a member of the TNF family. DR4, as many other receptors (Fas, TNFR1, etc.), mediates apoptosis and NF kappaB activation in many cells and tissues. Apoptosis, a programmed cell death, is a operating process in normal cellular differentiation and development of multicellular organisms. Apoptosis is induced by coupled of certain cytokines (TNF family - TNF, Fas ligand) and their death domain containing receptors (TNFR1, Fas receptor).Synonyms: APO2, DR4, Death receptor 4, TNF-related apoptosis-inducing ligand receptor 1, TNFRSF10A, TRAIL receptor 1, TRAIL-R1, Tumor necrosis factor receptor superfamily member 10A
- 基因ID
- 8797
- UniProt
- O00220
- 途径
- Apoptosis, Positive Regulation of Endopeptidase Activity
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