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GLI3 抗体 (AA 41-57)

GLI3 适用: 人, 小鼠, 大鼠, 犬, 小鸡, 猴, Chimpanzee, 非洲爪蟾 WB, IHC (p), EIA 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN401281
发货至: 中国
  • 抗原 See all GLI3 抗体
    GLI3 (GLI Family Zinc Finger 3 (GLI3))
    抗原表位
    • 7
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 41-57
    适用
    • 46
    • 23
    • 16
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    人, 小鼠, 大鼠, 犬, 小鸡, 猴, Chimpanzee, 非洲爪蟾
    宿主
    • 37
    • 7
    • 3
    克隆类型
    • 33
    • 14
    多克隆
    标记
    • 26
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    This GLI3 antibody is un-conjugated
    应用范围
    • 18
    • 14
    • 7
    • 7
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
    特异性
    This antibody is directed against Gli-3 protein.
    交叉反应 (详细)
    Species reactivity (expected):Chimpanzee, squirrel Monkey, Xenopus laevis, Chicken, Canine (100 %).Mouse (94 %).Rat (88 %).
    Species reactivity (tested):Human.
    纯化方法
    Immunoaffinity Chromatography.
    免疫原
    Synthetic peptide corresponding to amino acids 41-57 of Human Gli-3 protein
    亚型
    IgG
    Top Product
    Discover our top product GLI3 Primary Antibody
  • 应用备注
    ELISA: 1/6,000-1/30,000. Western blot: 1/500-1/2,000. Immunohistochemistry on Paraffin Sections: 0.5 mg/mL-5 μg/mL.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    限制
    仅限研究用
  • 浓度
    1.0 mg/mL (by UV absorbance at 280 nm)
    缓冲液
    0.02 M Potassium Phosphate, 0.12 M NaCl, pH 7.2, 0.09 % (w/v) Sodium Azide as preservative.
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    4 °C/-20 °C
    储存方法
    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.
  • 抗原
    GLI3 (GLI Family Zinc Finger 3 (GLI3))
    别名
    GLI3 (GLI3 产品)
    别名
    ACLS antibody, GCPS antibody, GLI3-190 antibody, GLI3FL antibody, PAP-A antibody, PAPA antibody, PAPA1 antibody, PAPB antibody, PHS antibody, PPDIV antibody, xgli3 antibody, AI854843 antibody, AU023367 antibody, Bph antibody, Pdn antibody, Xt antibody, add antibody, im:7142603 antibody, GLI3 antibody, GLI family zinc finger 3 antibody, GLI family zinc finger 3 L homeolog antibody, GLI-Kruppel family member GLI3 antibody, GLI3 antibody, Gli3 antibody, gli3.L antibody, gli3 antibody
    背景
    Gli-3 (also known as Zinc Finger Protein Gli-3 or GLI-Kruppel family member GLI-3) belongs to the GLI C2H2-type zinc-finger protein family and contains 5 C2H2-type zinc fingers. Gli-3 is very important for normal limb and brain development and is implicated in the transduction of Shh signal. Gli-3 is a nuclear protein expressed in a wide variety of normal adult tissues, including lung, colon, spleen, placenta, testis, and myometrium. Defects in Gli-3 are the cause of Greig cephalo-polysyndactyly syndrome (GCPS), an autosomal dominant disorder-affecting limb and craniofacial development. Two isoforms of human Gli-3 have been reported. One is the fulllength protein at ~170-190 kDa and the other is a truncated isoform at ~80 kDa.Synonyms: GLI-3, Zinc finger protein GLI3
    基因ID
    2737
    NCBI登录号
    NP_000159
    UniProt
    P10071
    途径
    Hedgehog Signaling
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