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GLI3 抗体 (AA 11-60)

The 兔 多克隆 anti-GLI3 antibody is suitable to detect GLI3 in samples from 人, 小鼠 和 大鼠. It has been validated for IHC, ELISA 和 IF.
产品编号 ABIN1533604
发货至: 中国
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北京 101111
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Room 801-803
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Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for GLI3 抗体 (AA 11-60) (ABIN1533604)

抗原

See all GLI3 抗体
GLI3 (GLI Family Zinc Finger 3 (GLI3))

适用

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人, 小鼠, 大鼠

宿主

  • 56
  • 5
  • 2
兔

克隆类型

  • 40
  • 23
多克隆

标记

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  • 3
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  • 3
  • 3
  • 3
  • 1
  • 1
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This GLI3 antibody is un-conjugated

应用范围

  • 38
  • 17
  • 15
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  • 13
  • 2
  • 2
  • 2
  • 2
  • 1
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Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF)
  • 抗原表位

    • 15
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 11-60

    原理

    GLI-3 Antibody

    特异性

    GLI-3 Polyclonal Antibody detects endogenous levels of GLI-3 protein.

    纯化方法

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

    纯度

    > 95 %

    免疫原

    The antiserum was produced against synthesized peptide derived from human GLI-3. AA range:11-60

    亚型

    IgG
  • 应用备注

    IHC 1:100 - 1:300. IF 1:200 - 1:1000. ELISA: 1:10000. Not yet tested in other applications.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C/1 year

    有效期

    12 months
  • 抗原

    GLI3 (GLI Family Zinc Finger 3 (GLI3))

    别名

    GLI-3

    背景

    Synonyms: GLI3, Transcriptional activator GLI3, GLI3 form of 190 kDa, GLI3-190, GLI3 full length protein, GLI3FL

    Background: This gene encodes a protein which belongs to the C2H2-type zinc finger proteins subclass of the Gli family. They are characterized as DNA-binding transcription factors and are mediators of Sonic hedgehog (Shh) signaling.The protein encoded by this gene localizes in the cytoplasm and activates patched Drosophila homolog (PTCH) gene expression. It is also thought to play a role during embryogenesis. Mutations in this gene have been associated with several diseases, including Greig cephalopolysyndactyly syndrome, Pallister-Hall syndrome, preaxial polydactyly type IV, and postaxial polydactyly types A1 and B. [provided by RefSeq, Jul 2008],

    Gene Name: GLI3

    Protein Name: Transcriptional activator GLI3

    分子量

    13 kDa

    基因ID

    2737

    UniProt

    P10071

    途径

    Hedgehog Signaling
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