FANCA 抗体 (AA 995-1009)
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- 抗原 See all FANCA 抗体
- FANCA (Fanconi Anemia Group A Protein (FANCA))
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抗原表位
- AA 995-1009
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适用
- 人, Chimpanzee
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This FANCA antibody is un-conjugated
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应用范围
- Western Blotting (WB), Enzyme Immunoassay (EIA)
- 特异性
- This antibody is directed against human FANCA protein.
- 交叉反应 （详细）
- Species reactivity (tested):Human, Chimpanzee.
- 纯化方法
- Immunoaffinity chromatography
- 免疫原
- Synthetic peptide corresponding to amino acids 995-1009 of human FANCA protein
- 亚型
- IgG
- Top Product
- Discover our top product FANCA Primary Antibody
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anti-Fanconi Anemia Group A Protein (FANCA) (N-Term) antibody
FANCA 适用: 人 WB, IF, IHC (p), ICC 宿主: 兔 Polyclonal unconjugated
anti-Fanconi Anemia Group A Protein (FANCA) (AA 995-1009) antibodyFANCA 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Fanconi Anemia Group A Protein (FANCA) (AA 1-297) antibodyFANCA 适用: 人 WB, IF 宿主: 小鼠 Polyclonal unconjugated
anti-Fanconi Anemia Group A Protein (FANCA) (AA 1121-1170), (pSer1149) antibodyFANCA 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Fanconi Anemia Group A Protein (FANCA) (pSer1149) antibodyFANCA 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Fanconi Anemia Group A Protein (FANCA) (AA 609-813) antibodyFANCA 适用: 人 ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Fanconi Anemia Group A Protein (FANCA) antibodyFANCA 适用: 人 IHC 宿主: 兔 Polyclonal unconjugated
anti-Fanconi Anemia Group A Protein (FANCA) (AA 71-120) antibodyFANCA 适用: 人, 猴, Cow WB 宿主: 兔 Polyclonal unconjugated
anti-Fanconi Anemia Group A Protein (FANCA) (N-Term) antibodyFANCA 适用: 人 WB, IHC, IHC (p), ICC 宿主: 兔 Polyclonal unconjugated
anti-Fanconi Anemia Group A Protein (FANCA) (AA 1-275) antibodyFANCA 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
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- 应用备注
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ELISA: 1: 15,000 - 1: 60,000. Western blot: 1: 500 - 1: 3,000 (Expect a main band at approximately 163 kDa in sizecorresponding to FANCA by western blotting in the appropriate cell lysate or extract orhuman tissue).
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. - 限制
- 仅限研究用
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- 浓度
- 1.45 mg/mL (by UV absorbance at 280 nm)
- 缓冲液
- 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2, 0.01 % (w/v) Sodium Azide
- 储存液
- Sodium azide
- 注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freezing and thawing. Should this product contain a precipitate we recommend microcentrifugation before use.
- 储存条件
- 4 °C/-20 °C
- 储存方法
- Store the antibody at 2 - 8 °C up to one month or (in aliquots) at -20 °C for longer.
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- 抗原
- FANCA (Fanconi Anemia Group A Protein (FANCA))
- 别名
- FANCA (FANCA 产品)
- 别名
- FA antibody, FA-H antibody, FA1 antibody, FAA antibody, FACA antibody, FAH antibody, FANCH antibody, AW208693 antibody, Fanconi anemia complementation group A antibody, Fanconi anemia, complementation group A antibody, FANCA antibody, Fanca antibody
- 背景
- FANCA (also called Protein FACA or Fanconi anemia group A protein) is involved in DNA repair, perhaps specifically with post-replication repair or a cell cycle checkpoint function. FANCA may also be implicated in interstrand DNA cross-link repair and in the maintenance of normal chromosome stability. The Fanconi anemia complementation group (FANC) currently includes FANCA, FANCB, FANCC, FANCD1 (also called BRCA2), FANCD2, FANCE, FANCF, FANCG, and FANCL. The previously defined group FANCH is the same as FANCA. Fanconi anemia is a genetically heterogeneous recessive disorder characterized by cytogenetic instability, hypersensitivity to DNA crosslinking agents, increased chromosomal breakage, and defective DNA repair. The members of the Fanconi anemia complementation group do not share sequence similarity, they are related by their assembly into a common nuclear protein complex. This gene encodes the protein for complementation group A. Alternative splicing results in multiple transcript variants encoding different isoforms. Variant 1 (isoform a) encodes the longest transcript. Variant 2 (isoform b) contains an alternate exon, which results in an early stop codon, compared to variant 1. Isoform b has a shorter C-terminus when compared to isoform a. Mutations in this gene are the most common cause of Fanconi anemia.Synonyms: FAA, FACA, FANCH, Fanconi anemia group A protein
- 基因ID
- 2175
- NCBI登录号
- NP_000126
- UniProt
- O15360
- 途径
- DNA Damage Repair
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