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FANCA 抗体 (pSer1149)

This 兔 多克隆 antibody specifically detects FANCA in WB, ELISA, IHC 和 IF. It exhibits reactivity toward 人, 小鼠 和 大鼠.
产品编号 ABIN1531711
发货至: 中国
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Room 801-803
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Quick Overview for FANCA 抗体 (pSer1149) (ABIN1531711)

抗原

See all FANCA 抗体
FANCA (Fanconi Anemia Group A Protein (FANCA))

适用

  • 73
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  • 2
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  • 1
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  • 1
人, 小鼠, 大鼠

宿主

  • 83
  • 3
兔

克隆类型

  • 73
  • 13
多克隆

标记

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  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
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  • 1
  • 1
  • 1
  • 1
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This FANCA antibody is un-conjugated

应用范围

  • 56
  • 34
  • 13
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  • 13
  • 12
  • 12
  • 11
  • 8
  • 5
  • 3
  • 1
  • 1
Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)
  • 抗原表位

    • 15
    • 13
    • 11
    • 7
    • 5
    • 4
    • 4
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
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    • 1
    • 1
    AA 1121-1170, pSer1149

    原理

    FANCA (phospho Ser1149) Antibody

    特异性

    Phospho-FANCA (S1149) Polyclonal Antibody detects endogenous levels of FANCA protein only when phosphorylated at S1149.

    纯化方法

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

    纯度

    > 95 %

    免疫原

    The antiserum was produced against synthesized peptide derived from human FANCA around the phosphorylation site of Ser1149. AA range:1121-1170

    亚型

    IgG
  • 应用备注

    WB 1:500 - 1:2000. IHC 1:100 - 1:300. IF 1:200 - 1:1000. ELISA: 1:5000. Not yet tested in other applications.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C/1 year

    有效期

    12 months
  • 抗原

    FANCA (Fanconi Anemia Group A Protein (FANCA))

    别名

    FANCA

    背景

    Synonyms: FANCA, FAA, FACA, FANCH, Fanconi anemia group A protein, Protein FACA

    Background: The Fanconi anemia complementation group (FANC) currently includes FANCA, FANCB, FANCC, FANCD1 (also called BRCA2), FANCD2, FANCE, FANCF, FANCG, FANCI, FANCJ (also called BRIP1), FANCL, FANCM and FANCN (also called PALB2). The previously defined group FANCH is the same as FANCA. Fanconi anemia is a genetically heterogeneous recessive disorder characterized by cytogenetic instability, hypersensitivity to DNA crosslinking agents, increased chromosomal breakage, and defective DNA repair. The members of the Fanconi anemia complementation group do not share sequence similarity, they are related by their assembly into a common nuclear protein complex.This gene encodes the protein for complementation group A. Alternative splicing results in multiple transcript variants encoding different isoforms. Mutations in this gene are the most common cause of Fanconi anemia. [provided by RefSeq, Jul

    Gene Name: FANCA

    Protein Name: Fanconi anemia group A protein

    分子量

    162 kDa

    基因ID

    2175

    OMIM

    227650

    UniProt

    O15360

    途径

    DNA Damage Repair
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