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RNF34 抗体 (N-Term)

RNF34 适用: 人, 小鼠, 大鼠, Cow, 犬, Orang-Utan WB, EIA 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN401035
发货至: 中国
  • 抗原 See all RNF34 抗体
    RNF34 (Ring Finger Protein 34 (RNF34))
    抗原表位
    • 9
    • 8
    • 6
    • 6
    • 3
    • 1
    • 1
    • 1
    AA 1-373, N-Term
    适用
    • 27
    • 5
    • 5
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    人, 小鼠, 大鼠, Cow, 犬, Orang-Utan
    宿主
    • 25
    • 2
    • 1
    克隆类型
    • 28
    多克隆
    标记
    • 19
    • 2
    • 2
    • 2
    • 2
    • 1
    This RNF34 antibody is un-conjugated
    应用范围
    • 26
    • 17
    • 3
    • 3
    • 2
    • 1
    • 1
    Western Blotting (WB), Enzyme Immunoassay (EIA)
    特异性
    This antibody is directed against RNF34 protein. Expect reactivity with isoform 1 and 2 of RNF34.
    交叉反应 (详细)
    Species reactivity (expected):Orangutan, Bovine, Canine, Mouse, Rat.
    Species reactivity (tested):Human.
    纯化方法
    Affinity chromatography on Protein A
    免疫原
    Recombinant protein corresponding to amino acids 1-373 of human RNF34 protein
    亚型
    IgG
    Top Product
    Discover our top product RNF34 Primary Antibody
  • 应用备注
    ELISA: 1/4,000 - 1/20,000. Western Blot: 1/500 - 1/3,000.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    限制
    仅限研究用
  • 溶解方式
    Restore with 0.1 mL of deionized water or equivalent.
    浓度
    5.0 mg/mL (by UV absorbance at 280 nm)
    缓冲液
    0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2 containing 0.01 % (w/v) Sodium Azide
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    4 °C/-20 °C
    储存方法
    Prior to reconstitution store at 2-8 °C. Following reconstitution store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.
  • 抗原
    RNF34 (Ring Finger Protein 34 (RNF34))
    别名
    RFI / RNF34 (RNF34 产品)
    别名
    CARP-1 antibody, CARP1 antibody, RFI antibody, RIF antibody, RIFF antibody, hRFI antibody, rnf34 antibody, AW061037 antibody, AW536122 antibody, BC004042 antibody, C88279 antibody, Momo antibody, fi35g06 antibody, wu:fi35g06 antibody, zgc:114043 antibody, zgc:171755 antibody, ring finger protein 34 antibody, E3 ubiquitin-protein ligase RNF34 antibody, ring finger protein 34a antibody, ring finger protein 34b antibody, Residual feed intake antibody, RNF34 antibody, rnf34 antibody, Rnf34 antibody, rnf34a antibody, rnf34b antibody, RFI antibody
    背景
    RNF34, also known as RING finger protein 34, RING finger protein RIFF, FYVE-RING finger protein Momo, Human RING finger homologous to inhibitor of apoptosis protein, hRFI, Caspases-8 and -10-associated RING finger protein 1, CARP-1 and Caspase regulator CARP1, is a novel modulator of NF-kappaB activation. RNF34 possesses E3 ubiquitin protein ligase activity and has been shown to regulate the levels of CASP8 and CASP10 by targeting them for proteasomal degradation. RNF34 protects cells against apoptosis induced by TNF and may bind phosphatidylinositol phosphates. RNF34 is localized to both the nucleus and the cytoplasm. In the nucleus, a distinct speckled pattern is observed by immunofluorescence microscopy. In the cytoplasm, the protein is associated with membranes. RNF34 is expressed ubiquitously and can be detected in heart, brain, liver, skeletal muscle, kidney, pancreas, spleen, thymus, prostate, testis, ovary, colon and leukocytes. Multiple transcript variants have been reported for this protein.Synonyms: CARP-1, CARP1, Caspases-8 and -10-associated RING finger protein 1, E3 ubiquitin-protein ligase RNF34, FYVE-RING finger protein Momo, Human RING finger homologous to inhibitor of apoptosis protein, RIFF
    基因ID
    80196
    NCBI登录号
    NP_079402
    UniProt
    Q969K3
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