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- 抗原 See all RNF34 抗体
- RNF34 (Ring Finger Protein 34 (RNF34))
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抗原表位
- AA 1-220
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This RNF34 antibody is un-conjugated
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应用范围
- Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
- 交叉反应
- 人
- 纯化方法
- Antigen Affinity Purified
- 免疫原
- Recombinant Human E3 ubiquitin-protein ligase RNF34 protein (1-220AA)
- 亚型
- IgG
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anti-Ring Finger Protein 34 (RNF34) (AA 1-373) antibody
RNF34 适用: 人 WB, IF 宿主: 小鼠 Polyclonal unconjugated
anti-Ring Finger Protein 34 (RNF34) (AA 143-192) antibodyRNF34 适用: 人, Cow, 兔, 豚鼠, 猴 WB 宿主: 兔 Polyclonal unconjugated
anti-Ring Finger Protein 34 (RNF34) (AA 1-373) antibodyRNF34 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
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- 应用备注
- Recommended dilution: WB:1:1000-1:5000, IHC:1:20-1:200,
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C,-80 °C
- 储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- 抗原
- RNF34 (Ring Finger Protein 34 (RNF34))
- 别名
- RNF34 (RNF34 产品)
- 别名
- CARP-1 antibody, CARP1 antibody, RFI antibody, RIF antibody, RIFF antibody, hRFI antibody, rnf34 antibody, AW061037 antibody, AW536122 antibody, BC004042 antibody, C88279 antibody, Momo antibody, fi35g06 antibody, wu:fi35g06 antibody, zgc:114043 antibody, zgc:171755 antibody, ring finger protein 34 antibody, E3 ubiquitin-protein ligase RNF34 antibody, ring finger protein 34a antibody, ring finger protein 34b antibody, Residual feed intake antibody, RNF34 antibody, rnf34 antibody, Rnf34 antibody, rnf34a antibody, rnf34b antibody, RFI antibody
- 背景
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Background: E3 ubiquitin-protein ligase that regulates several biological processes through the ubiquitin-mediated proteasomal degradation of various target proteins. Ubiquitinates the caspases CASP8 and CASP10, promoting their proteasomal degradation, to negatively regulate cell death downstream of death domain receptors in the extrinsic pathway of apoptosis (PubMed:15069192). May mediate \\\'Lys-48\\\'-linked polyubiquitination of RIPK1 and its subsequent proteasomal degradation thereby indirectly regulating the tumor necrosis factor-mediated signaling pathway (Ref.13). Negatively regulates p53/TP53 through its direct ubiquitination and targeting to proteasomal degradation (PubMed:17121812). Indirectly, may also negatively regulate p53/TP53 through ubiquitination and degradation of SFN (PubMed:18382127). Mediates PPARGC1A proteasomal degradation probably through ubiquitination thereby indirectly regulating the metabolism of brown fat cells (PubMed:22064484). Possibly involved in innate immunity, through \\\'Lys-48\\\'-linked polyubiquitination of NOD1 and its subsequent proteasomal degradation (PubMed:25012219).
Aliases: CARP 1 antibody, CARP-1 antibody, CARP1 antibody, Caspase regulator CARP1 antibody, Caspases-8 and -10-associated RING finger protein 1 antibody, E3 ubiquitin-protein ligase RNF34 antibody, FYVE-RING finger protein Momo antibody, hRFI antibody, Human RING finger homologous to inhibitor of apoptosis protein antibody, RFI antibody, RIF antibody, RIFF antibody, RING finger protein 34 antibody, RING finger protein RIFF antibody, RNF34 antibody, RNF34_HUMAN antibody
- UniProt
- Q969K3
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