RFFL 抗体 (N-Term)
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- 抗原 See all RFFL 抗体
- RFFL (Ring Finger and FYVE-Like Domain Containing 1 (RFFL))
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抗原表位
- AA 1-363, N-Term
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适用
- 人, 小鼠, 大鼠, Cow, 犬
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This RFFL antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
- 特异性
- This antibody is directed against RFFL protein.
- 交叉反应 （详细）
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Species reactivity (expected):Canine, Rat, Mouse, Bovine.
Species reactivity (tested):Human. - 纯化方法
- Affinity chromatography on Protein A
- 免疫原
- Recombinant protein corresponding to amino acids 1-363 of human RFFL protein
- 亚型
- IgG
- Top Product
- Discover our top product RFFL Primary Antibody
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anti-Ring Finger and FYVE-Like Domain Containing 1 (RFFL) (AA 2-99) antibody
RFFL 适用: 人 WB, ELISA, RNAi 宿主: 小鼠 Monoclonal 3A4 unconjugated
anti-Ring Finger and FYVE-Like Domain Containing 1 (RFFL) (AA 1-190) antibodyRFFL 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Ring Finger and FYVE-Like Domain Containing 1 (RFFL) (AA 265-294), (C-Term) antibodyRFFL 适用: 人 WB 宿主: 兔 Polyclonal RB40306 unconjugated
anti-Ring Finger and FYVE-Like Domain Containing 1 (RFFL) (AA 251-363) antibodyRFFL 适用: 人, 小鼠 WB, ELISA, IF (cc), IF (p), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Ring Finger and FYVE-Like Domain Containing 1 (RFFL) (AA 2-99) antibodyRFFL 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-Ring Finger and FYVE-Like Domain Containing 1 (RFFL) antibodyRFFL 适用: 人, 小鼠, 大鼠 WB 宿主: 兔 Polyclonal unconjugated
anti-Ring Finger and FYVE-Like Domain Containing 1 (RFFL) (AA 287-336) antibodyRFFL 适用: 人, 小鼠, 大鼠, 马, 兔, 猴 WB 宿主: 兔 Polyclonal unconjugated
anti-Ring Finger and FYVE-Like Domain Containing 1 (RFFL) (N-Term) antibodyRFFL 适用: 人, 小鼠, Cow, 马, 豚鼠, 猴 WB 宿主: 兔 Polyclonal unconjugated
anti-Ring Finger and FYVE-Like Domain Containing 1 (RFFL) (AA 1-190) antibodyRFFL 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Ring Finger and FYVE-Like Domain Containing 1 (RFFL) (AA 1-363) antibodyRFFL 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
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- 应用备注
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ELISA: 1/4000 - 1/20000. Western Blot: 1/500 - 1/3000. Immunohistochemistry: 1/500 - 1/3000.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. - 限制
- 仅限研究用
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- 溶解方式
- Restore with 0.1 mL of deionized water or equivalent.
- 浓度
- 5.0 mg/mL (by UV absorbance at 280 nm)
- 缓冲液
- 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2 containing 0.01 % (w/v) Sodium Azide
- 储存液
- Sodium azide
- 注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freezing and thawing.
- 储存条件
- 4 °C/-20 °C
- 储存方法
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.
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- 抗原
- RFFL (Ring Finger and FYVE-Like Domain Containing 1 (RFFL))
- 别名
- RFFL / RNF189 (RFFL 产品)
- 别名
- MGC84042 antibody, RFFL antibody, Rffl antibody, 1700051E09Rik antibody, 4930516L10Rik antibody, BG080975 antibody, Carp2 antibody, CARP-2 antibody, CARP2 antibody, FRING antibody, RIFIFYLIN antibody, RNF189 antibody, RNF34L antibody, ring finger and FYVE like domain containing E3 ubiquitin protein ligase antibody, ring finger and FYVE-like domain containing E3 ubiquitin protein ligase L homeolog antibody, ring finger and FYVE-like domain containing 1 antibody, ring finger and FYVE like domain containing protein antibody, ring finger and FYVE-like domain containing E3 ubiquitin protein ligase antibody, RFFL antibody, rffl.L antibody, Rffl antibody
- 背景
- RFFL, also known as Rififylin, RING finger and FYVE-like domaincontaining protein 1, FYVE-RING finger protein, Sakura, Fring, Caspases-8 and -10-associated RING finger protein 2, CARP-2, Caspase regulator CARP2, RING finger protein 189 and RING finger protein 34-like, is a novel modulator of NF-kappaB activation. RFFL possesses E3 ubiquitin protein ligase activity and has been shown to regulate the levels of CASP8 and CASP10 by targeting them for proteasomal degradation. RFFL also possesses anti-apoptotic activity and may bind phosphatidylinositol phosphates. RFFL is a membrane bound cytoplasmic protein that is expressed ubiquitously. RFFL can be detected in spleen, thymus, prostate, testis, ovary, small intestine, colon and peripheral blood leukocytes and is rapidly degraded after stimulation with TNFSF10, and probably by caspases. Multiple transcript variants have been detected for this protein.Synonyms: CARP-2, CARP2, Caspases-8 and -10-associated RING finger protein 2, E3 ubiquitin-protein ligase rififylin, FYVE-RING finger protein Sakura, Fring, RIFIFYLIN, RING finger protein 189, RING finger protein 34-like, RNF34L
- 基因ID
- 117584
- NCBI登录号
- NP_001017368
- UniProt
- Q8WZ73
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