电话:
400-7060-959
传真:
+86 10 56315212-8813
电子邮件:
orders@antibodies-online.cn

MUSK 抗体 (N-Term)

MUSK 适用: 人 WB, FACS, IHC (p) 宿主: 兔 Polyclonal RB01497 unconjugated
产品编号 ABIN392019
发货至: 中国
  • 抗原 See all MUSK 抗体
    MUSK (Muscle, Skeletal, Receptor Tyrosine Kinase (MUSK))
    抗原表位
    • 15
    • 11
    • 8
    • 7
    • 7
    • 5
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 35-65, N-Term
    适用
    • 72
    • 31
    • 26
    • 6
    • 6
    • 5
    • 2
    • 2
    • 1
    • 1
    • 1
    宿主
    • 67
    • 8
    • 2
    克隆类型
    • 72
    • 8
    多克隆
    标记
    • 39
    • 5
    • 4
    • 4
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This MUSK antibody is un-conjugated
    应用范围
    • 67
    • 36
    • 30
    • 13
    • 13
    • 13
    • 10
    • 4
    • 4
    • 3
    • 3
    • 3
    • 1
    • 1
    Western Blotting (WB), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    预测反应
    M, Rat
    纯化方法
    This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
    免疫原
    This MUSK antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 35-65 amino acids from the N-terminal region of human MUSK.
    克隆位点
    RB01497
    亚型
    Ig Fraction
    Top Product
    Discover our top product MUSK Primary Antibody
  • 应用备注
    WB: 1:1000. WB: 1:1000. WB: 1:1000. IHC-P: 1:10~50. FC: 1:10~50
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    储存方法
    Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
    有效期
    6 months
  • Chevessier, Faraut, Ravel-Chapuis, Richard, Gaudon, Bauché, Prioleau, Herbst, Goillot, Ioos, Azulay, Attarian, Leroy, Fournier, Legay, Schaeffer, Koenig, Fardeau, Eymard, Pouget, Hantaï: "[Pathophysiological characterization of congenital myasthenic syndromes: the example of mutations in the MUSK gene]." in: Journal de la Société de biologie, Vol. 199, Issue 1, pp. 61-77, (2005) (PubMed).

    Chevessier, Faraut, Ravel-Chapuis, Richard, Gaudon, Bauché, Prioleau, Herbst, Goillot, Ioos, Azulay, Attarian, Leroy, Fournier, Legay, Schaeffer, Koenig, Fardeau, Eymard, Pouget, Hantaï: "MUSK, a new target for mutations causing congenital myasthenic syndrome." in: Human molecular genetics, Vol. 13, Issue 24, pp. 3229-40, (2004) (PubMed).

  • 抗原
    MUSK (Muscle, Skeletal, Receptor Tyrosine Kinase (MUSK))
    别名
    MUSK (MUSK 产品)
    别名
    unp antibody, fj98e12 antibody, zgc:63467 antibody, wu:fj98e12 antibody, si:dz46m7.2 antibody, si:dz57f23.3 antibody, si:busm1-57f23.3 antibody, musk-A antibody, MuSK antibody, MUSK antibody, Mdk4 antibody, Mlk antibody, Nsk1 antibody, Nsk2 antibody, Nsk3 antibody, muscle antibody, muscle associated receptor tyrosine kinase antibody, muscle, skeletal, receptor tyrosine kinase antibody, muscle associated receptor tyrosine kinase S homeolog antibody, MUSK antibody, musk antibody, musk.S antibody, Musk antibody
    背景
    Protein kinases are enzymes that transfer a phosphate group from a phosphate donor, generally the g phosphate of ATP, onto an acceptor amino acid in a substrate protein. By this basic mechanism, protein kinases mediate most of the signal transduction in eukaryotic cells, regulating cellular metabolism, transcription, cell cycle progression, cytoskeletal rearrangement and cell movement, apoptosis, and differentiation. With more than 500 gene products, the protein kinase family is one of the largest families of proteins in eukaryotes. The family has been classified in 8 major groups based on sequence comparison of their tyrosine (PTK) or serine/threonine (STK) kinase catalytic domains. The tyrosine kinase (TK) group is mainly involved in the regulation of cell-cell interactions such as differentiation, adhesion, motility and death. There are currently about 90 TK genes sequenced, 58 are of receptor protein TK (e.g. EGFR, EPH, FGFR, PDGFR, TRK, and VEGFR families), and 32 of cytosolic TK (e.g. ABL, FAK, JAK, and SRC families).
    分子量
    97056
    基因ID
    4593
    NCBI登录号
    NP_001159752, NP_001159753, NP_005583
    UniProt
    O15146
    途径
    RTK signaling, Regulation of Muscle Cell Differentiation, Synaptic Membrane, Regulation of Cell Size, Skeletal Muscle Fiber Development
You are here:
客服