MUSK 抗体
Our Local Distributor
北京 101111
Quick Overview for MUSK 抗体 (ABIN3031879)
抗原
See all MUSK 抗体适用
宿主
克隆类型
标记
应用范围
-
-
纯化方法
- Purified
-
免疫原
- This MUSK antibody was produced from rabbits immunized with human MUSK recombinant protein.
-
亚型
- Ig Fraction
-
-
-
-
应用备注
- Titration of the MUSK antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000,Flow Cytometry: 1:10-1:50,Immunofluorescence: 1:10-1:50
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
缓冲液
- In 1X PBS pH 7.4 with 0.09 % sodium azide
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
储存条件
- -20 °C
-
储存方法
- Aliquot the MUSK antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
-
-
- MUSK (Muscle, Skeletal, Receptor Tyrosine Kinase (MUSK))
-
别名
- MUSK
-
背景
- MuSK activates signaling cascades responsible for many aspects of synapse formation, including the organization of the postsynaptic membrane, synapse-specific transcription, and presynaptic differentiation. MuSK also mediates agrin-induced aggregation of acetylcholine receptors at the mature vertebrate neuromuscular junction and also during synapse formation. It has been shown that a majority of AChR Ab-seronegative myasthenia gravis patients possess serum autoantibodies against MuSK.
-
UniProt
- O15146
-
途径
- RTK signaling, Regulation of Muscle Cell Differentiation, Synaptic Membrane, Regulation of Cell Size, Skeletal Muscle Fiber Development
抗原
-