DAAM1 抗体 (C-Term)
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- 抗原 See all DAAM1 抗体
- DAAM1 (Dishevelled Associated Activator of Morphogenesis 1 (DAAM1))
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抗原表位
- AA 1034-1063, C-Term
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This DAAM1 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- 纯化方法
- This antibody is purified through a protein A column, followed by peptide affinity purification.
- 免疫原
- This DAAM1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1034-1063 amino acids from the C-terminal region of human DAAM1.
- 克隆位点
- RB10612
- 亚型
- Ig Fraction
- Top Product
- Discover our top product DAAM1 Primary Antibody
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- 应用备注
- WB: 1:1000. IHC-P: 1:10~50
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 储存方法
- Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
- 有效期
- 6 months
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DAAM1 stabilizes epithelial junctions by restraining WAVE complex-dependent lateral membrane motility." in: The Journal of cell biology, Vol. 215, Issue 4, pp. 559-573, (2017) (PubMed).
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DAAM1 stabilizes epithelial junctions by restraining WAVE complex-dependent lateral membrane motility." in: The Journal of cell biology, Vol. 215, Issue 4, pp. 559-573, (2017) (PubMed).
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- 抗原
- DAAM1 (Dishevelled Associated Activator of Morphogenesis 1 (DAAM1))
- 别名
- DAAM1 (DAAM1 产品)
- 别名
- 1700066F09Rik antibody, 2310028E21Rik antibody, AI503486 antibody, E130308H01 antibody, mKIAA0666 antibody, daam-1 antibody, xdaam1 antibody, daam1 antibody, DAAM1 antibody, DKFZp468D0524 antibody, daam1l antibody, fc83b10 antibody, si:ch211-87i20.1 antibody, wu:fc83b10 antibody, dishevelled associated activator of morphogenesis 1 antibody, dishevelled associated activator of morphogenesis 1 S homeolog antibody, dishevelled associated activator of morphogenesis 1a antibody, dishevelled associated activator of morphogenesis 1b antibody, DAAM1 antibody, Daam1 antibody, daam1.S antibody, daam1a antibody, daam1 antibody, daam1b antibody
- 背景
- Functions of the cell cortex, including motility, adhesion, and cytokinesis, are mediated by the reorganization of the actin cytoskeleton and recent evidence suggests a role for the Formin homology (FH) proteins in these processes. DAAM1 contains FH domains and belongs to a novel FH protein subfamily implicated in cell polarity. Wnt/Fz signaling activates the small GTPase Rho, a key regulator of cytoskeleton architecture, to control cell polarity and movement during development. Activation requires Dvl-Rho complex formation, an assembly mediated by DAAM1, which is thought to function as a scaffolding protein.
- 分子量
- 123473
- 基因ID
- 23002
- NCBI登录号
- NP_001257449, NP_055807
- UniProt
- Q9Y4D1
- 途径
- WNT signaling
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