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CD45 抗体 (APC)

PTPRC 适用: 小鸡 FACS 宿主: 小鼠 Monoclonal LT40 APC
产品编号 ABIN375806
发货至: 中国
  • 抗原 See all CD45 (PTPRC) 抗体
    CD45 (PTPRC) (Protein tyrosine Phosphatase, Receptor Type, C (PTPRC))
    适用
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    小鸡
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    小鼠
    克隆类型
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    单克隆
    标记
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    This CD45 antibody is conjugated to APC
    应用范围
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    Flow Cytometry (FACS)
    特异性
    Chicken CD45, Mr 190-215 kDa
    产品特性
    Mouse Anti-Chicken CD45-APC
    纯化方法
    Purified
    免疫原
    Chicken bursal lymphocytes
    克隆位点
    LT40
    亚型
    IgM
    Top Product
    Discover our top product PTPRC Primary Antibody
  • 应用备注
    • Applications: FC - Quality tested , IHC-FS - Reported in literature , IHC-PS - Reported in literature , IHC-WM - Reported in literature , ICC - Reported in literature , IP - Reported in literature , Sep - Reported in literature
    • Working Dilutions: Flow Cytometry FITC, BIOT, and AF488 conjugates 1 g/106 cells PE, APC, and SPRD conjugates 0.2 g/106 cells For flow cytometry, the suggested use of these reagents is in a final volume of 100 L
    样本量
    1 mL
    限制
    仅限研究用
  • 浓度
    0.1 mg/mL
    缓冲液
    0.1 mg in 1.0 mL of PBS/Sodium azide and a stabilizing agent
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Do not freeze!
    Protect conjugated products from light.

    Each reagent is stable for the period shown on the bottle label if stored as directed.
    储存条件
    4 °C
    储存方法
    Store at 2-8°C
  • Matulova, Stepanova, Sisak, Havlickova, Faldynova, Kyrova, Volf, Rychlik: "Cytokine signaling in splenic leukocytes from vaccinated and non-vaccinated chickens after intravenous infection with salmonella enteritidis." in: PLoS ONE, Vol. 7, Issue 2, pp. e32346, (2012) (PubMed).

  • 抗原
    CD45 (PTPRC) (Protein tyrosine Phosphatase, Receptor Type, C (PTPRC))
    别名
    CD45 (PTPRC 产品)
    别名
    PTPRC antibody, si:dkeyp-47c5.1 antibody, B220 antibody, CD45 antibody, CD45R antibody, GP180 antibody, L-CA antibody, LCA antibody, LY5 antibody, T200 antibody, Cd45 antibody, Ly-5 antibody, Lyt-4 antibody, loc antibody, Lca antibody, RT7 antibody, cd45 antibody, protein tyrosine phosphatase, receptor type C antibody, protein tyrosine phosphatase, receptor type, C antibody, receptor-type tyrosine-protein phosphatase C antibody, PTPRC antibody, ptprc antibody, LOC100074271 antibody, Ptprc antibody
    背景
    Chicken CD45 is a transmembrane glycoprotein expressed on all leukocytes. B lineage cells in the bursa of Fabricius express the 215 kDa isoform while T lineage cells bear the 190 kDa variant. These high molecular weight molecules have intrinsic phosphotyrosine phosphatase activity characteristic of mammalian CD45. 1 Levels of CD45 expression detected by MAb LT40 in the avian thymus are heterogeneous with approximately 90 % of thymocytes expressing fourfold higher levels of surface CD45 (CD45 hi ) than do the remaining 10 % (CD45 lo ) of thymocytes. The CD45 lo population contains exclusively thymocytes with the CD3 - CD4 - CD8 lo phenotype characteristic of the immediate precursors to the CD3 - CD4 + CD8 + thymic population which are CD45 hi. This shift from low to high levels of surface CD45 expression is concomitant with the transition from CD4 - CD8 lo to CD4 + CD8 + and before the expression of CD3.
    途径
    TCR Signaling, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, CXCR4-mediated Signaling Events, BCR Signaling
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