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GSK3 alpha 抗体 (N-Term)
GSK3a
适用: 人, 小鼠, 大鼠
WB
宿主: 小鼠
Monoclonal
SBGSK3a1
unconjugated
GSK3 alpha抗体详情
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抗原
See all GSK3 alpha (GSK3a) 抗体
GSK3 alpha (GSK3a)
(Glycogen Synthase Kinase 3 alpha (GSK3a))
抗原表位
All epitopes for GSK3 alpha 抗体
N-Term
适用
All reactivities for GSK3 alpha 抗体
人, 小鼠, 大鼠
宿主
All hosts for GSK3 alpha 抗体
小鼠
克隆类型
All clonalities for GSK3 alpha 抗体
单克隆
标记
All conjugates for GSK3 alpha 抗体
This GSK3 alpha antibody is un-conjugated
应用范围
All applications for GSK3 alpha 抗体
Western Blotting (WB)
特异性
Human/Mouse GSK-3α
产品特性
Mouse Anti-GSK-3a-UNLB
纯化方法
Purified
免疫原
Recombinant N-terminal GSK-3alpha
克隆位点
SBGSK3a1
亚型
IgG2a
Top Product
Discover our top product GSK3a Primary Antibody
Alternatives
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使用细节
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应用备注
Applications: WB - Quality tested Working Dilutions: Immunoblotting Purified (UNLB) antibody ≤ 2 g/mL HRP conjugate 1:1,000 - 1:5,000
样本量
0,2 mL
限制
仅限研究用
贮存及处理
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浓度
0.5 mg/mL
缓冲液
0.1 mg of purified immunoglobulin in 0.2 mL of borate buffered saline, pH 8.2. No preservatives or amine-containing buffer salts added
储存液
Without preservative
注意事项
Each reagent is stable for the period shown on the bottle label if stored as directed.
储存条件
4 °C
储存方法
Store at 2-8°C
GSK3 alpha目标详情
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抗原
GSK3 alpha (GSK3a)
(Glycogen Synthase Kinase 3 alpha (GSK3a))
别名
GSK-3a (GSK3a 产品 )
别名
2700086H06Rik antibody, GSK3A antibody, GSK-3[a] antibody, GSK-3[b] antibody, GSK3 antibody, gsk3a antibody, xgsk3 antibody, glycogen synthase kinase 3 alpha antibody, glycogen synthase kinase 3 alpha b antibody, glycogen synthase kinase 3 alpha S homeolog antibody, GSK3A antibody, Gsk3a antibody, gsk3a antibody, gsk3ab antibody, gsk3a.S antibody, Bm1_31380 antibody
背景
Glycogen synthase kinase-3 (GSK-3) is a protein serine kinase that phosphorylates glycogen synthase and thereby inactivates it. Insulin stimulates the dephosphorylation of glycogen synthase at the sites phosphorylated by GSK-3 and subsequently inhibits GSK-3 acutely leading to the stimulation of glycogen synthesis. GSK-3 signaling is performed by two isoforms, GSK-3 α and GSK-3β. The two isoforms share 97 % sequence similarity within their catalytic domains. GSK-3 has also been shown to play a role in protein synthesis, cell adhesion, cell proliferation, cell differentiation, microtubule dynamics and cell motility.
途径
PI3K-Akt Signaling , WNT signaling , Fc-epsilon Receptor Signaling Pathway , EGFR Signaling Pathway , Neurotrophin Signaling Pathway , cAMP Metabolic Process , Cellular Glucan Metabolic Process , Regulation of Muscle Cell Differentiation , Regulation of G-Protein Coupled Receptor Protein Signaling , ER-Nucleus Signaling , Regulation of Carbohydrate Metabolic Process , BCR Signaling , Warburg Effect
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