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FGF21 抗体 (Internal Region)

FGF21 适用: 人 WB 宿主: 山羊 Polyclonal unconjugated
产品编号 ABIN374880
发货至: 中国
  • 抗原 See all FGF21 抗体
    FGF21 (Fibroblast Growth Factor 21 (FGF21))
    抗原表位
    • 18
    • 5
    • 4
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Internal Region
    适用
    • 66
    • 29
    • 19
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    宿主
    • 67
    • 14
    • 1
    • 1
    • 1
    山羊
    克隆类型
    • 61
    • 23
    多克隆
    标记
    • 53
    • 7
    • 6
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    This FGF21 antibody is un-conjugated
    应用范围
    • 45
    • 35
    • 25
    • 11
    • 10
    • 7
    • 7
    • 5
    • 4
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB)
    序列
    CQRPDGALYG SLH
    特异性
    This antibody detects FGF21.
    交叉反应 (详细)
    Species reactivity (tested):Human
    纯化方法
    ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide
    免疫原
    Peptide from the internal region of the protein sequence according to NP_061986.1.
    Top Product
    Discover our top product FGF21 Primary Antibody
  • 应用备注
    Peptide ELISA: limit dilution 1: 2000. Western blot: 1-3 μg/mL. Approx 22 kDa band observed in Human Liver lysates (calculatedMW of 22.2 kDa according to NP_061986.1).
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    限制
    仅限研究用
  • 浓度
    0.5 mg/mL
    缓冲液
    Tris saline, 0.02 % sodium azide, pH 7.3 with 0.5 % bovine serum albumin
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    4 °C/-20 °C
    储存方法
    Store the antibody at 2 - 8 °C up to one month or (in aliquots) at -20 °C for longer.
  • Cyphert, Ge, Kohan, Salati, Zhang, Hillgartner: "Activation of the farnesoid X receptor induces hepatic expression and secretion of fibroblast growth factor 21." in: The Journal of biological chemistry, Vol. 287, Issue 30, pp. 25123-38, (2012) (PubMed).

  • 抗原
    FGF21 (Fibroblast Growth Factor 21 (FGF21))
    别名
    FGF21 (FGF21 产品)
    别名
    FGF21 antibody, fibroblast growth factor 21 antibody, FGF21 antibody, fgf21 antibody, Fgf21 antibody
    背景
    FGF21 is a growth factor that is a member of the FGF family. Proteins of this family play a central role during prenatal development and postnatal growth and regeneration of a variety of tissues, by promoting cellular proliferation and differentiation. FGF21, in the presence of betaKlotho as a protein cofactor, signals through the FGFR 1c and 4 receptors and stimulates insulin independent glucose uptake by adipocytes.Synonyms: FGF-21, Fibroblast growth factor 21
    基因ID
    26291, 9606
    UniProt
    Q9NSA1
    途径
    RTK signaling
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