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Angiotensin II Type-1 Receptor 抗体 (Internal Region)

Name: Angiotensin II Type-1 Receptor 抗体 (Internal Region)
SKU: ABIN374853
Availability: OutOfStock

AGTR1 适用: 人, 大鼠, 小鼠 WB 宿主: 山羊 Polyclonal unconjugated

Image no. 1 for anti-Angiotensin II Receptor, Type 1 (AGTR1) (Internal Region) antibody (ABIN374853) (Angiotensin II Type-1 Receptor 抗体 (Internal Region))

1 image

产品编号 ABIN374853

发货至: 中国

Datasheet as PDF

抗原 See all Angiotensin II Type-1 Receptor (AGTR1) 抗体

Angiotensin II Type-1 Receptor (AGTR1) (Angiotensin II Receptor, Type 1 (AGTR1))
抗原表位
16

9

6

3

3

2

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1
Internal Region
适用
50

23

21

5

4

3

3

2

2

1

1

1

1
人, 大鼠, 小鼠
宿主
48

3

2

1

1
山羊
Compatible Secondaries
克隆类型
52

3
多克隆
标记
33

4

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1
This Angiotensin II Type-1 Receptor antibody is un-conjugated
应用范围
32

23

17

15

13

10

9

8

6

4

3

2

2

2
Western Blotting (WB)

序列

C-EIQKNKPRND DIFK

特异性

This antibody recognizes AGTR1 / AT1.

纯化方法

Ammonium Sulphate Precipitation followed by Antigen Affinity Chromatography using the immunizing peptide

免疫原

Peptide with sequence from the internal region of the protein sequence according to NP_000676.1, NP_004826.2, NP_033611.1, NP_114038.1, NP_114438.1.

Top Product

Discover our top product AGTR1 Primary Antibody
anti-Angiotensin II Receptor, Type 1 (AGTR1) (N-Term) antibody
AGTR1 适用: 人, 大鼠, 小鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated

anti-Angiotensin II Receptor, Type 1 (AGTR1) (AA 211-240) antibody
AGTR1 适用: 人 WB, FACS, IF, IHC (p) 宿主: 兔 Polyclonal RB19701 unconjugated

anti-Angiotensin II Receptor, Type 1 (AGTR1) (AA 4-18), (Extracellular), (N-Term) antibody
AGTR1 适用: 人, 大鼠, 小鼠 WB, IHC, FACS, IF, ICC, LCI 宿主: 兔 Polyclonal unconjugated

anti-Angiotensin II Receptor, Type 1 (AGTR1) (AA 306-356) antibody
AGTR1 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated

anti-Angiotensin II Receptor, Type 1 (AGTR1) (AA 201-250) antibody
AGTR1 适用: 人, 大鼠, 小鼠 WB, ELISA, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated

anti-Angiotensin II Receptor, Type 1 (AGTR1) antibody
AGTR1 适用: 人, 大鼠, 小鼠, Cow WB, IF (p), IHC (p) 宿主: 兔 Polyclonal unconjugated

anti-Angiotensin II Receptor, Type 1 (AGTR1) (N-Term) antibody
AGTR1 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated

anti-Angiotensin II Receptor, Type 1 (AGTR1) (Internal Region) antibody
Verified AGTR1 适用: 人, 小鼠 WB, ELISA 宿主: 山羊 Polyclonal unconjugated

anti-Angiotensin II Receptor, Type 1 (AGTR1) (AA 4-18), (Extracellular), (N-Term) antibody (Atto 550)
AGTR1 适用: 人, 大鼠, 小鼠 IHC, IF, ICC, LCI 宿主: 兔 Polyclonal Atto 550

anti-Angiotensin II Receptor, Type 1 (AGTR1) (AA 263-359) antibody
AGTR1 适用: 大鼠 WB, IHC, ICC, IP 宿主: 兔 Polyclonal unconjugated

应用备注

Peptide ELISA: 1/32000. Western Blot: 0.3 - 1 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

限制

仅限研究用
浓度

0.5 mg/mL

缓冲液

Tris saline, pH ~7.3 containing 0.02 % Sodium Azide as preservative and 0.5 % BSA as stabilizer

储存液

Sodium azide

注意事项

This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

注意事项

Avoid repeated freezing and thawing.

储存条件

4 °C/-20 °C

储存方法

Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
抗原

Angiotensin II Type-1 Receptor (AGTR1) (Angiotensin II Receptor, Type 1 (AGTR1))

别名

Type-1 Angiotensin II Receptor (AT1) (AGTR1 产品)

别名

AG2S antibody, AGTR1A antibody, AGTR1B antibody, AT1 antibody, AT1AR antibody, AT1B antibody, AT1BR antibody, AT1R antibody, AT2R1 antibody, AT2R1A antibody, AT2R1B antibody, HAT1R antibody, 1810074K20Rik antibody, AI551199 antibody, AT1a antibody, Agtr-1a antibody, Agtr1 antibody, Angtr-1a antibody, AT1A antibody, XAT-1 antibody, agtr1-A antibody, agtr1.2 antibody, AT1-R antibody, at1 antibody, AGTR1 antibody, Agtr-1b antibody, Angtr-1b antibody, agtr1 antibody, agtr1-a antibody, agtr1-b antibody, xAT antibody, angiotensin II receptor type 1 antibody, angiotensin II receptor, type 1a antibody, angiotensin II receptor type 1 S homeolog antibody, uncharacterized AGTR1 antibody, angiotensin II receptor, type 1b antibody, angiotensin II receptor type 1 L homeolog antibody, AGTR1 antibody, Agtr1a antibody, agtr1.S antibody, Agtr1 antibody, Agtr1b antibody, agtr1.L antibody

背景

Type 1 Angiotensin Receptors (AT1A and AT1B) mediate the major cardiovascular effects of angiotensin II, controlling blood pressure and volume by regulating cell growth, vascular contraction, inflammatory responses, and salt and water retention. Stimulation of AT1 receptors by Ang II activates phospholipase C beta, resulting in increased intracellular calcium and inositol 1, 4, 5-triphosphate concentrations, and activatesthe mitogen-activated protein kinases, such as extracellular regulated kinases, by way of Src and Ras as well as the JAK/STAT pathways. AT1 knock-out mice have lower blood pressure than wild type mice and lose normal pressor response to exogenous Ang II. AT1B differs from AT1A in its mRNA tissue distribution and in the 5' untranslated region. AT1 blockers have become widely used in the treatment of hypertension and may offer benefits other than blood pressure reduction.Synonyms: AGTR1, AGTR1A, AGTR1B, AT1AR, AT1BR, AT2R1, AT2R1B

基因ID

185, 9606

UniProt

P30556

途径

JAK/STAT Signaling, ACE Inhibitor Pathway, Regulation of Systemic Arterial Blood Pressure by Hormones, Feeding Behaviour