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Angiotensin II Type-1 Receptor 抗体 (AA 211-240)

The 兔 多克隆 anti-Angiotensin II Type-1 Receptor antibody (Clone RB19701) (ABIN654078) specifically detects Angiotensin II Type-1 Receptor in WB, IF, FACS 和 IHC (p). The antibody is reactive with 人 samples.
产品编号 ABIN654078
发货至: 中国
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Quick Overview for Angiotensin II Type-1 Receptor 抗体 (AA 211-240) (ABIN654078)

抗原

See all Angiotensin II Type-1 Receptor (AGTR1) 抗体
Angiotensin II Type-1 Receptor (AGTR1) (Angiotensin II Receptor, Type 1 (AGTR1))

适用

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宿主

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克隆类型

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多克隆

标记

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This Angiotensin II Type-1 Receptor antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunofluorescence (IF), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

克隆位点

RB19701
  • 抗原表位

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    AA 211-240

    预测反应

    Pig, Rb

    纯化方法

    This antibody is purified through a protein A column, followed by peptide affinity purification.

    免疫原

    This AGTR1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 211-240 amino acids from the Central region of human AGTR1.

    亚型

    Ig Fraction
  • 应用备注

    IF: 1:25. WB: 1:2000. WB: 1:1000. IHC-P: 1:10~50. FC: 1:10~50

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

    有效期

    6 months
  • 抗原

    Angiotensin II Type-1 Receptor (AGTR1) (Angiotensin II Receptor, Type 1 (AGTR1))

    别名

    AGTR1

    背景

    Angiotensin II is a potent vasopressor hormone and a primary regulator of aldosterone secretion. It is an important effector controlling blood pressure and volume in the cardiovascular system. It acts through at least two types of receptors. This gene encodes the type 1 receptor which is thought to mediate the major cardiovascular effects of angiotensin II. This gene may play a role in the generation of reperfusion arrhythmias following restoration of blood flow to ischemic or infarcted myocardium. It was previously thought that a related gene, denoted as AGTR1B, existed, however, it is now believed that there is only one type 1 receptor gene in humans. At least five transcript variants have been described for this gene. Additional variants have been described but their full-length nature has not been determined. The entire coding sequence is contained in the terminal exon and is present in all transcript variants. [provided by RefSeq].

    分子量

    41061

    基因ID

    185

    NCBI登录号

    NP_000676, NP_033611

    UniProt

    P30556

    途径

    JAK/STAT Signaling, ACE Inhibitor Pathway, Regulation of Systemic Arterial Blood Pressure by Hormones, Feeding Behaviour
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