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Angiotensin II Type-1 Receptor 抗体 (N-Term)

Name: Angiotensin II Type-1 Receptor 抗体 (N-Term)
SKU: ABIN3043531
Availability: OutOfStock

AGTR1 适用: 人, 小鼠 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated

Anti- AGTR1 Picoband antibody, Western blotting All lanes: Anti AGTR1 at 0. (Angiotensin II Type-1 Receptor 抗体 (N-Term))

Anti- AGTR1 Picoband antibody, IHC(P) IHC(P): Human Mammary Cancer Tissue (Angiotensin II Type-1 Receptor 抗体 (N-Term))

IHC

2 images

(2 references)

产品编号 ABIN3043531

发货至: 中国

Datasheet as PDF

抗原 See all Angiotensin II Type-1 Receptor (AGTR1) 抗体

Angiotensin II Type-1 Receptor (AGTR1) (Angiotensin II Receptor, Type 1 (AGTR1))
抗原表位
16

9

6

3

3

2

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1
AA 1-28, N-Term
适用
50

23

21

5

4

3

3

2

2

1

1

1

1
人, 小鼠
宿主
48

3

2

1

1
兔
Compatible Secondaries
克隆类型
52

3
多克隆
标记
33

4

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1
This Angiotensin II Type-1 Receptor antibody is un-conjugated
应用范围
32

23

17

15

13

10

9

8

6

4

3

2

2

2
Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

原理

Rabbit IgG polyclonal antibody for Type-1 angiotensin II receptor(AGTR1) detection. Tested with WB, IHC-P in Human,Mouse.

序列

MILNSSTEDG IKRIQDDCPK AGRHNYIF

交叉反应（详细）

No cross reactivity with other proteins.

产品特性

Rabbit IgG polyclonal antibody for Type-1 angiotensin II receptor(AGTR1) detection. Tested with WB, IHC-P in Human,Mouse.
Gene Name: angiotensin II receptor, type 1
Protein Name: Type-1 angiotensin II receptor

纯化方法

Immunogen affinity purified.

免疫原

A synthetic peptide corresponding to a sequence at the N-terminus of human AGTR1 (1-28aa MILNSSTEDGIKRIQDDCPKAGRHNYIF), different from the related mouse and rat sequences by one amino acid.

亚型

IgG

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Discover our top product AGTR1 Primary Antibody
anti-Angiotensin II Receptor, Type 1 (AGTR1) (N-Term) antibody
AGTR1 适用: 人, 大鼠, 小鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated

anti-Angiotensin II Receptor, Type 1 (AGTR1) (AA 211-240) antibody
AGTR1 适用: 人 WB, FACS, IF, IHC (p) 宿主: 兔 Polyclonal RB19701 unconjugated

anti-Angiotensin II Receptor, Type 1 (AGTR1) (AA 4-18), (Extracellular), (N-Term) antibody
AGTR1 适用: 人, 大鼠, 小鼠 WB, IHC, FACS, IF, ICC, LCI 宿主: 兔 Polyclonal unconjugated

anti-Angiotensin II Receptor, Type 1 (AGTR1) (AA 306-356) antibody
AGTR1 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated

anti-Angiotensin II Receptor, Type 1 (AGTR1) (AA 201-250) antibody
AGTR1 适用: 人, 大鼠, 小鼠 WB, ELISA, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated

anti-Angiotensin II Receptor, Type 1 (AGTR1) antibody
AGTR1 适用: 人, 大鼠, 小鼠, Cow WB, IF (p), IHC (p) 宿主: 兔 Polyclonal unconjugated

anti-Angiotensin II Receptor, Type 1 (AGTR1) (N-Term) antibody
AGTR1 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated

anti-Angiotensin II Receptor, Type 1 (AGTR1) (Internal Region) antibody
Verified AGTR1 适用: 人, 小鼠 WB, ELISA 宿主: 山羊 Polyclonal unconjugated

anti-Angiotensin II Receptor, Type 1 (AGTR1) (AA 4-18), (Extracellular), (N-Term) antibody (Atto 550)
AGTR1 适用: 人, 大鼠, 小鼠 IHC, IF, ICC, LCI 宿主: 兔 Polyclonal Atto 550

anti-Angiotensin II Receptor, Type 1 (AGTR1) (AA 263-359) antibody
AGTR1 适用: 大鼠 WB, IHC, ICC, IP 宿主: 兔 Polyclonal unconjugated

应用备注

WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human, Mouse
IHC-P: Concentration: 0.5-1 μg/mL, Tested Species: Human, Epitope Retrieval by Heat: Boiling the paraffin sections in 10 mM citrate buffer, pH 6.0, for 20 mins is required for the staining of formalin/paraffin sections.
Notes: Tested Species: Species with positive results. Other applications have not been tested. Optimal dilutions should be determined by end users.

说明

Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).

限制

仅限研究用
状态

Lyophilized

溶解方式

Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

浓度

500 μg/mL

缓冲液

Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.

储存液

Sodium azide

注意事项

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

注意事项

Avoid repeated freezing and thawing.

储存条件

4 °C/-20 °C

储存方法

At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.
Wu, Dai, Ren, Liu, Li, Chang et al.: "Angiotensin II induces apoptosis of human pulmonary microvascular endothelial cells in acute aortic dissection complicated with lung injury patients through modulating the expression of monocyte ..." in: American journal of translational research, Vol. 8, Issue 1, pp. 28-36, (2016) (PubMed).

Liu, Wang, Wu, Zhang: "Effects of angiotensin II receptor antagonist, Losartan on the apoptosis, proliferation and migration of the human pancreatic stellate cells." in: World journal of gastroenterology, Vol. 11, Issue 41, pp. 6489-94, (2006) (PubMed).
抗原

Angiotensin II Type-1 Receptor (AGTR1) (Angiotensin II Receptor, Type 1 (AGTR1))

别名

AGTR1 (AGTR1 产品)

别名

AG2S antibody, AGTR1A antibody, AGTR1B antibody, AT1 antibody, AT1AR antibody, AT1B antibody, AT1BR antibody, AT1R antibody, AT2R1 antibody, AT2R1A antibody, AT2R1B antibody, HAT1R antibody, 1810074K20Rik antibody, AI551199 antibody, AT1a antibody, Agtr-1a antibody, Agtr1 antibody, Angtr-1a antibody, AT1A antibody, XAT-1 antibody, agtr1-A antibody, agtr1.2 antibody, AT1-R antibody, at1 antibody, AGTR1 antibody, Agtr-1b antibody, Angtr-1b antibody, agtr1 antibody, agtr1-a antibody, agtr1-b antibody, xAT antibody, angiotensin II receptor type 1 antibody, angiotensin II receptor, type 1a antibody, angiotensin II receptor type 1 S homeolog antibody, uncharacterized AGTR1 antibody, angiotensin II receptor, type 1b antibody, angiotensin II receptor type 1 L homeolog antibody, AGTR1 antibody, Agtr1a antibody, agtr1.S antibody, Agtr1 antibody, Agtr1b antibody, agtr1.L antibody

背景

AGTR1 is known as Angiotensin II Type 1 Receptor. Angiotensin II is a potent vasopressor hormone and a primary regulator of aldosterone secretion. It is an important effector controlling blood pressure and volume in the cardiovascular system. And it acts through at least two types of receptors. This gene encodes the type 1 receptor which is thought to mediate the major cardiovascular effects of angiotensin II. Moreover, this gene may play a role in the generation of reperfusion arrhythmias following restoration of blood flow to ischemic or infarcted myocardium. It was previously thought that a related gene, denoted as AGTR1B, existed, however, it is now believed that there is only one type 1 receptor gene in humans. Multiple alternatively spliced transcript variants have been reported for this gene.

Synonyms: AG2S antibody|Agtr 1 antibody|Agtr1 antibody|AGTR1_HUMAN antibody|Agtr1a antibody|AGTR1B antibody|Ang II antibody| Angiotensin II receptor type 1 antibody|Angiotensin II type-1 receptor antibody|Angiotensin receptor 1 antibody|Angiotensin receptor 1B antibody|AT 1B antibody|AT 1r antibody|AT1 antibody|At1a antibody|AT1AR antibody|AT1B antibody|AT1BR antibody|AT1R antibody|AT2R1 antibody|AT2R1A antibody|AT2R1B antibody|HAT1R antibody|Type 1 angiotensin II receptor antibody|Type 1B angiotensin II receptor antibody|Type-1 angiotensin II receptor antibody

基因ID

185

UniProt

P30556

途径

JAK/STAT Signaling, ACE Inhibitor Pathway, Regulation of Systemic Arterial Blood Pressure by Hormones, Feeding Behaviour