Angiotensin II Type-1 Receptor 抗体 (N-Term)
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Quick Overview for Angiotensin II Type-1 Receptor 抗体 (N-Term) (ABIN3043531)
抗原
See all Angiotensin II Type-1 Receptor (AGTR1) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 1-28, N-Term
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原理
- Anti-Angiotensin II Type 1 Receptor/AGTR1 Antibody
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序列
- MILNSSTEDG IKRIQDDCPK AGRHNYIF
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交叉反应 （详细）
- No cross-reactivity with other proteins
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产品特性
- Anti-Angiotensin II Type 1 Receptor/AGTR1 Antibody (ABIN3043531). Tested in IHC, WB applications. This antibody reacts with Human, Monkey, Mouse, Rat. This is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications.
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纯化方法
- Immunogen affinity purified.
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免疫原
- A synthetic peptide corresponding to a sequence at the N-terminus of human AGTR1, different from the related mouse and rat sequences by one amino acid.
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亚型
- IgG
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anti-Angiotensin II Receptor, Type 1 (AGTR1) (AA 4-18), (Extracellular) antibody
AGTR1 适用: 人 WB, IHC, IF, FACS, LCI, IC 宿主: 兔 Polyclonal unconjugated
anti-Angiotensin II Receptor, Type 1 (AGTR1) (N-Term) antibodyAGTR1 适用: 人, 大鼠, 小鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Angiotensin II Receptor, Type 1 (AGTR1) (AA 211-240) antibodyAGTR1 适用: 人 WB, IF, FACS, IHC (p) 宿主: 兔 Polyclonal RB19701 unconjugated
anti-Angiotensin II Receptor, Type 1 (AGTR1) (AA 306-356) antibodyAGTR1 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Angiotensin II Receptor, Type 1 (AGTR1) (AA 201-250) antibodyAGTR1 适用: 人, 大鼠, 小鼠 WB, ELISA, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Angiotensin II Receptor, Type 1 (AGTR1) antibodyAGTR1 适用: 人, 大鼠, 小鼠, Cow WB, IF (p), IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Angiotensin II Receptor, Type 1 (AGTR1) (Internal Region) antibodyVerified AGTR1 适用: 人, 小鼠 WB, ELISA 宿主: 山羊 Polyclonal unconjugated
anti-Angiotensin II Receptor, Type 1 (AGTR1) (N-Term) antibodyAGTR1 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Angiotensin II Receptor, Type 1 (AGTR1) (AA 4-18), (Extracellular) antibody (Atto 550)AGTR1 适用: 人 IHC, IF, LCI, IC 宿主: 兔 Polyclonal Atto 550
anti-Angiotensin II Receptor, Type 1 (AGTR1) (AA 263-359) antibodyAGTR1 适用: 大鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
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应用备注
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Immunohistochemistry (Paraffin-embedded Section), 0.5-1 μg/mL, Human
Western blot, 0.1-0.5 μg/mL, Human, Monkey, Mouse, Rat
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说明
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Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl and 0.2 mg Na2HPO4.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C,-20 °C
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储存方法
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Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
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: "Angiotensin II induces apoptosis of human pulmonary microvascular endothelial cells in acute aortic dissection complicated with lung injury patients through modulating the expression of monocyte ..." in: American journal of translational research, Vol. 8, Issue 1, pp. 28-36, (2016) (PubMed).
: "Effects of angiotensin II receptor antagonist, Losartan on the apoptosis, proliferation and migration of the human pancreatic stellate cells." in: World journal of gastroenterology, Vol. 11, Issue 41, pp. 6489-94, (2006) (PubMed).
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: "Angiotensin II induces apoptosis of human pulmonary microvascular endothelial cells in acute aortic dissection complicated with lung injury patients through modulating the expression of monocyte ..." in: American journal of translational research, Vol. 8, Issue 1, pp. 28-36, (2016) (PubMed).
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- Angiotensin II Type-1 Receptor (AGTR1) (Angiotensin II Receptor, Type 1 (AGTR1))
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别名
- AGTR1
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背景
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Synonyms: Type-1 angiotensin II receptor,AT1AR,AT1BR,Angiotensin II type-1 receptor,AT1,AGTR1,AGTR1A, AGTR1B, AT2R1, AT2R1B,
Tissue Specificity: Liver, lung, adrenal and adrenocortical adenomas.
Background: AGTR1 is known as Angiotensin II Type 1 Receptor. Angiotensin II is a potent vasopressor hormone and a primary regulator of aldosterone secretion. It is an important effector controlling blood pressure and volume in the cardiovascular system. And it acts through at least two types of receptors. This gene encodes the type 1 receptor which is thought to mediate the major cardiovascular effects of angiotensin II. Moreover, this gene may play a role in the generation of reperfusion arrhythmias following restoration of blood flow to ischemic or infarcted myocardium. It was previously thought that a related gene, denoted as AGTR1B, existed, however, it is now believed that there is only one type 1 receptor gene in humans. Multiple alternatively spliced transcript variants have been reported for this gene.
Sequence Similarities: Belongs to the G-protein coupled receptor 1 family.
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分子量
- 50 kDa
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基因ID
- 185
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UniProt
- P30556
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途径
- JAK/STAT Signaling, ACE Inhibitor Pathway, Regulation of Systemic Arterial Blood Pressure by Hormones, Feeding Behaviour
抗原
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