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FE65 抗体 (C-Term)

APBB1 适用: 人 WB 宿主: 山羊 Polyclonal unconjugated
产品编号 ABIN374723
发货至: 中国
  • 抗原 See all FE65 (APBB1) 抗体
    FE65 (APBB1) (Amyloid beta (A4) Precursor Protein-Binding, Family B, Member 1 (Fe65) (APBB1))
    抗原表位
    • 15
    • 15
    • 15
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term
    适用
    • 56
    • 37
    • 28
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    宿主
    • 58
    • 1
    • 1
    山羊
    克隆类型
    • 60
    多克隆
    标记
    • 18
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    This FE65 antibody is un-conjugated
    应用范围
    • 59
    • 39
    • 39
    • 14
    • 10
    • 9
    • 2
    • 1
    • 1
    Western Blotting (WB)
    特异性
    This antibody reacts to APBB1 / FE65.
    纯化方法
    Affinity chromatography
    免疫原
    Peptide with sequence C-GSLKPKRLGAHTP, from the C Terminus of the protein sequence
    Top Product
    Discover our top product APBB1 Primary Antibody
  • 应用备注
    Peptide ELISA: 1/128000. Western Blot: 0.1 - 0.3 μg/mL.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    限制
    仅限研究用
  • 浓度
    0.5 mg/mL
    缓冲液
    Tris saline, 0.02 % sodium azide, pH 7.3 with 0.5 % bovine serum albumin
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    4 °C/-20 °C
    储存方法
    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • 抗原
    FE65 (APBB1) (Amyloid beta (A4) Precursor Protein-Binding, Family B, Member 1 (Fe65) (APBB1))
    别名
    APBB1 / FE65 (APBB1 产品)
    别名
    FE65 antibody, MGC:9072 antibody, RIR antibody, apbb1 antibody, MGC80654 antibody, Fe65 antibody, Rir antibody, amyloid beta precursor protein binding family B member 1 antibody, amyloid beta (A4) precursor protein-binding, family B, member 1 (Fe65) L homeolog antibody, amyloid beta (A4) precursor protein-binding, family B, member 1 antibody, APBB1 antibody, apbb1.L antibody, Apbb1 antibody
    背景
    Amyloid precursor protein (APP), which plays a central role in the pathogenesis of Alzheimer's disease (AD), is a cell-surface protein that is cleaved by gamma-secretase at the transmembrane region into an extracellular amyloid-beta peptide (Ab) and an intracellular tail fragment. This cytoplasmic tail of APP forms a multimeric complex with the nuclear adaptor protein FE65 and the histone acetyltransferase Tip60.1 FE65 is an adaptor protein that bridges APP to certain molecular pathways. FE65 is also highly expressed in neurons and possesses the characteristics of a transcription factor. The interaction between APP and FE65 increases the translocation of APP to the cell surface and the subsequent secretion of Ab. FE65 is thus important in the regulation and trafficking of APP.Synonyms: Amyloid beta A4 precursor protein-binding family B member 1, RIR
    基因ID
    322, 9606
    UniProt
    O00213
    途径
    Positive Regulation of Response to DNA Damage Stimulus
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