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FBXW2 抗体 (C-Term)

FBXW2 适用: 人, 小鼠, 大鼠, Cow, 犬, Pig WB, IHC (p) 宿主: 山羊 Polyclonal unconjugated
产品编号 ABIN374352
发货至: 中国
  • 抗原 See all FBXW2 抗体
    FBXW2 (F-Box and WD Repeat Domain Containing 2 (FBXW2))
    抗原表位
    • 15
    • 6
    • 4
    • 1
    • 1
    • 1
    C-Term
    适用
    • 29
    • 6
    • 5
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    人, 小鼠, 大鼠, Cow, 犬, Pig
    宿主
    • 27
    • 1
    • 1
    山羊
    克隆类型
    • 29
    多克隆
    标记
    • 11
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This FBXW2 antibody is un-conjugated
    应用范围
    • 13
    • 13
    • 10
    • 10
    • 5
    • 3
    • 3
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    序列
    C-KRGSSFLAGE HPG
    特异性
    This antibody detects FBXW2 / FBW2 / FWD2 at C-term.
    交叉反应 (详细)
    Species reactivity (expected):Canine (Dog), Pig, Bovine.
    Species reactivity (tested):Human, Mouse, Rat.
    纯化方法
    Ammonium Sulphate Precipitation followed by Antigen Affinity Chromatography using the immunizing peptide
    免疫原
    Synthetic peptide from C-Terminus of the protein sequence according to NP_036296.1 Genename: FBXW2
    Top Product
    Discover our top product FBXW2 Primary Antibody
  • 应用备注
    Peptide ELISA: Limit dilution 1: 128000. Western blot: 0.3-1.5 μg/mL. Approx 48 kDa band observed in Human Kidney lysates(calculated MW of 48.8 kDa according to NP_036296.1). A stronger band of unknownidentity was also consistently observed at appr.38 kDa - both bands were successfullyblocked by incubation with the immunising peptide. Immunohistochemistry: 2-3 μg/mL. In paraffin embedded Human Kidney, showscytoplasmic staining of epithelial cells in some renal tubules.
    限制
    仅限研究用
  • 浓度
    0.5 mg/mL
    缓冲液
    Tris saline, pH ~7.3, 0.02 % Sodium Azide, 0.5 % BSA
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    4 °C/-20 °C
    储存方法
    Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • 抗原
    FBXW2 (F-Box and WD Repeat Domain Containing 2 (FBXW2))
    别名
    FBXW2 / FBW2 / FWD2 (FBXW2 产品)
    别名
    FBXW2 antibody, md6 antibody, fbw2 antibody, fwd2 antibody, MGC53244 antibody, FBW2 antibody, Fwd2 antibody, Md6 antibody, wu:fc72f10 antibody, zgc:110365 antibody, 2700071L08Rik antibody, MD6 antibody, F-box and WD repeat domain containing 2 antibody, F-box and WD repeat domain containing 2 L homeolog antibody, F-box and WD-40 domain protein 2 antibody, FBXW2 antibody, fbxw2 antibody, Fbxw2 antibody, fbxw2.L antibody
    背景
    F box proteins are an expanding family of eukaryotic proteins characterized by an approximately 40 amino acid motif, the F box. Some F box proteins have been shown to be critical for the ubiquitin mediated degradation of cellular regulatory proteins. In fact, F box proteins are one of the four subunits of ubiquitin protein ligases, called SCFs. SCF ligases bring ubiquitin conjugating enzymes to substrates that are specifically recruited by the different F box proteins. A large family of mammalian F box proteins has recently been identified and classified into three groups based on the presence of either the WD 40 repeats, the leucine rich repeats, or the presence or absence of other protein protein interacting domains. The FBXW2 gene product, the second identified member of the F box gene family, contains multiple WD 40 repeats.Synonyms: F-box and WD-40 domain-containing protein 2, F-box/WD repeat-containing protein 2, Protein MD6
    基因ID
    26190
    NCBI登录号
    NP_036296
    UniProt
    Q9UKT8
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