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IRF5 抗体 (C-Term)

IRF5 适用: 人, 小鼠, 大鼠, Cow WB, IP, IHC (p), ChIP, EIA 宿主: 山羊 Polyclonal unconjugated
产品编号 ABIN374255
发货至: 中国
  • 抗原 See all IRF5 抗体
    IRF5 (Interferon Regulatory Factor 5 (IRF5))
    抗原表位
    • 9
    • 7
    • 7
    • 6
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term
    适用
    • 71
    • 48
    • 22
    • 6
    • 5
    • 5
    • 4
    • 4
    • 3
    • 3
    • 3
    人, 小鼠, 大鼠, Cow
    宿主
    • 73
    • 9
    • 1
    • 1
    山羊
    克隆类型
    • 65
    • 19
    多克隆
    标记
    • 52
    • 6
    • 5
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    This IRF5 antibody is un-conjugated
    应用范围
    • 48
    • 30
    • 12
    • 11
    • 10
    • 6
    • 6
    • 6
    • 2
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunoprecipitation (IP), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Chromatin Immunoprecipitation (ChIP), Enzyme Immunoassay (EIA)
    序列
    C-QGPWPMHPAG MQ
    特异性
    This antibody is expected to recognize all four reported isoforms.
    交叉反应 (详细)
    Species reactivity (expected):Mouse, Rat, Cow.
    Species reactivity (tested):Human.
    纯化方法
    Ammonium Sulphate Precipitation followed by Antigen Affinity Chromatography using the immunizing peptide
    免疫原
    Peptide from C Terminus of the protein sequence according to NP_002191.1, NP_116032.1, NP_001092097.1, NP_001092099.1. Genename: IRF5
    Top Product
    Discover our top product IRF5 Primary Antibody
  • 应用备注
    Peptide ELISA: Limit dilution 1: 32000. Western blot: 0.1-0.3 μg/mL. Approx 57 kDa band observed in lysates of cell line A549. Intransfected HEK293 transiently expressing IRF5 a strong band of approx.67 kDa isobserved. This band is not observed in the non-transfected HEK293.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    限制
    仅限研究用
  • 浓度
    0.5 mg/mL
    缓冲液
    Tris saline, pH ~7.3 containing 0.02 % Sodium Azide as preservative and 0.5 % BSA as stabilizer
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    4 °C/-20 °C
    储存方法
    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C.
  • 抗原
    IRF5 (Interferon Regulatory Factor 5 (IRF5))
    别名
    IRF5 (IRF5 产品)
    别名
    IRF5 antibody, irf5 antibody, SLEB10 antibody, AW491843 antibody, mirf5 antibody, im:7155364 antibody, zgc:76986 antibody, interferon regulatory factor 5 antibody, interferon regulatory factor 5 L homeolog antibody, IRF5 antibody, irf5 antibody, Irf5 antibody, irf5.L antibody
    背景
    Interferon regulatory factors (IRFs) are transcription factors that possess a novel helix turn helix DNA binding motif and mediate virus and interferon (IFN) induced signaling pathways. The IRF5 protein is structurally related to IRF6. Like other IRFs, IRF5 and IRF6 contain 5 conserved tryptophan residues in the 115 amino acid N terminal DNA binding domain. IRF5 has a central IRF association domain (IAD) and, like IRF7 and IRF8, is induced by IFNA/IFNB stimulation. IRF5 has a type I IFN transactivation potential similar to that of IRF1. IRF3 and IRF5 form heterodimers and are both required for effective induction of IFNA gene transcription.Synonyms: IRF-5, Interferon regulatory factor 5
    基因ID
    3663
    NCBI登录号
    NP_002191
    UniProt
    Q13568
    途径
    TLR signaling, Autophagy
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