NMDA 1 Receptor 抗体 (Splice Variant N1)
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- 抗原 See all NMDA 1 Receptor (NMDA R1) 抗体
- NMDA 1 Receptor (NMDA R1) (NMDA Receptor 1 (NMDA R1))
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抗原表位
- Splice Variant N1
- 适用
- 人, 大鼠, 小鼠, 犬, Non-Human Primate, 小鸡, 非洲爪蟾
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This NMDA 1 Receptor antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunohistochemistry (Frozen Sections) (IHC (fro))
- 特异性
- This antibody recognizes the ~120k NR1 subunit, N1 splice variant insert protein of the NMDA Receptor. It Does not recognize NR1 subunits of the NMDA Receptor that do not contain the N1 insert.
- 交叉反应 （详细）
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Species reactivity (expected):Canine, Chicken, Human, Xenopus and non-Human Primates.
Species reactivity (tested):Mouse and Rat. - 纯化方法
- Affinity Chromatography.
- 免疫原
- Peptide from the NR1 subunit, N1 splice variant insert of Rat NMDA Receptor.
- 亚型
- IgG
- Top Product
- Discover our top product NMDA R1 Primary Antibody
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anti-NMDA Receptor 1 (NMDA R1) (AA 35-53) antibody
NMDA R1 适用: 人, 大鼠, 小鼠 WB, ELISA, IP 宿主: 兔 Polyclonal unconjugated
anti-NMDA Receptor 1 (NMDA R1) (AA 35-53) antibodyNMDA R1 适用: 人, 大鼠, 小鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-NMDA Receptor 1 (NMDA R1) (AA 1-564), (N-Term) antibodyNMDA R1 适用: 大鼠, 小鼠 WB, IHC (fro), IP 宿主: 小鼠 Monoclonal R1JHL unconjugated
anti-NMDA Receptor 1 (NMDA R1) (Splice Variant C2) antibodyNMDA R1 适用: 人, 大鼠, 小鼠 WB, IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-NMDA Receptor 1 (NMDA R1) (Splice Variant C2') antibodyNMDA R1 适用: 人, 大鼠, 小鼠, Cow WB, IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-NMDA Receptor 1 (NMDA R1) (AA 894-898) antibodyNMDA R1 适用: 人, 小鼠 WB 宿主: 兔 Polyclonal unconjugated
anti-NMDA Receptor 1 (NMDA R1) (pSer896) antibodyNMDA R1 适用: 人, 小鼠 WB 宿主: 兔 Polyclonal unconjugated
anti-NMDA Receptor 1 (NMDA R1) (AA 895-899) antibodyNMDA R1 适用: 人, 大鼠, 小鼠 IF 宿主: 兔 Polyclonal unconjugated
anti-NMDA Receptor 1 (NMDA R1) (pSer897) antibodyNMDA R1 适用: 人, 大鼠, 小鼠 IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-NMDA Receptor 1 (NMDA R1) antibodyNMDA R1 适用: 人, 大鼠, 小鼠 WB, IHC (p), IF, EIA 宿主: 兔 Polyclonal unconjugated
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- 应用备注
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Western blot: 1/1000. Immunohistochemistry on Frozen Sections: 1/1000-1/2000.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. - 限制
- 仅限研究用
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- 溶解方式
- Restore in 50 μL PBS (137 mM NaCl, 7.5 mM Na2HPO4, 2.7 mM KCl, 1.5 mM KH2PO4, pH 7.4) before use.
- 缓冲液
- 5 mM Ammonium Bicarbonate.
- 注意事项
- Avoid repeated freezing and thawing.
- 储存条件
- -20 °C
- 储存方法
- Store the antibody undiluted (in aliquots) at-20 °C.
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- 抗原
- NMDA 1 Receptor (NMDA R1) (NMDA Receptor 1 (NMDA R1))
- 别名
- NMDA Receptor 1 (NMDA R1 产品)
- 别名
- CG2902 antibody, DMNMDAR1 antibody, DNMDAR-I antibody, DNmdar antibody, DmelNmdar1 antibody, Dmel\\CG2902 antibody, DrNR1 antibody, NMDA antibody, NMDA R1 antibody, NMDAR1 antibody, NMdar1 antibody, NR1 antibody, NRI antibody, Nmdar antibody, dNR1 antibody, dnmdar-I antibody, nmr antibody, NMDA receptor 1 antibody, Nmdar1 antibody
- 背景
- The ion channels activated by glutamate are typically divided into two classes. Glutamate receptors that are activated by kainate and alpha-amino-3-hydroxy-5-methyl-4-isoxalone propionic acid (AMPA) are known as kainate/AMPA receptors (K/AMPAR). Those that are sensitive to N-methyl-D-aspartate (NMDA) are designated NMDA receptors (NMDAR). The NMDAR plays an essential role in memory, neuronal development and it has also been implicated in several disorders of the central nervous system including Alzheimer's, epilepsy and ischemic neuronal cell death (Grosshans et al., 2002, Wenthold et al., 2003, Carroll and Zukin, 2002). The NMDA receptor is also one of the principal molecular targets for alcohol in the CNS (Lovinger et al., 1989, Alvestad et al., 2003, Snell et al., 1996). The NMDAR is also potentiated by protein phosphorylation (Lu et al., 1999). The rat NMDAR1 (NR1) was the first subunit of the NMDAR to be cloned. The NR1 protein can form NMDA activated channels when expressed in Xenopus oocytes but the currents in such channels are much smaller than those seen in situ. Channels with more physiological characteristics are produced when the NR1 subunit is combined with one or more of the NMDAR2 (NR2 A-D) subunits.Synonyms: GRIN1, Glutamate [NMDA] receptor subunit zeta-1, NMDAR1
- 基因ID
- 24408
- NCBI登录号
- NP_058706
- UniProt
- P35439
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