NMDA 1 Receptor 抗体 (N-Term)
(4 references)-
- 抗原 See all NMDA 1 Receptor (NMDA R1) 抗体
- NMDA 1 Receptor (NMDA R1) (NMDA Receptor 1 (NMDA R1))
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抗原表位
- AA 1-564, N-Term
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适用
- 大鼠, 小鼠
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This NMDA 1 Receptor antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunoprecipitation (IP)
- 特异性
- This antibody is specific for the ~120k NR1 subunit of the NMDA Receptor.
- 交叉反应 （详细）
- Species reactivity (tested):Rat and Mouse.
- 产品特性
- Synonyms: NMDAR1, GRIN1, Glutamate [NMDA] receptor subunit zeta-1
- 纯化方法
- Supernatant.
- 免疫原
- Fusion protein containing amino acids 1-564 of the NR1 subunit of rat NMDA receptor.
- 克隆位点
- R1JHL
- 亚型
- IgG1
- Top Product
- Discover our top product NMDA R1 Primary Antibody
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anti-NMDA Receptor 1 (NMDA R1) (AA 35-53) antibody
NMDA R1 适用: 人, 大鼠, 小鼠 WB, ELISA, IP 宿主: 兔 Polyclonal unconjugated
anti-NMDA Receptor 1 (NMDA R1) (AA 35-53) antibodyNMDA R1 适用: 人, 大鼠, 小鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-NMDA Receptor 1 (NMDA R1) (Splice Variant C2) antibodyNMDA R1 适用: 人, 大鼠, 小鼠 WB, IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-NMDA Receptor 1 (NMDA R1) (Splice Variant C2') antibodyNMDA R1 适用: 人, 大鼠, 小鼠, Cow WB, IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-NMDA Receptor 1 (NMDA R1) (AA 894-898) antibodyNMDA R1 适用: 人, 小鼠 WB 宿主: 兔 Polyclonal unconjugated
anti-NMDA Receptor 1 (NMDA R1) (pSer896) antibodyNMDA R1 适用: 人, 小鼠 WB 宿主: 兔 Polyclonal unconjugated
anti-NMDA Receptor 1 (NMDA R1) (AA 895-899) antibodyNMDA R1 适用: 人, 大鼠, 小鼠 IF 宿主: 兔 Polyclonal unconjugated
anti-NMDA Receptor 1 (NMDA R1) (pSer897) antibodyNMDA R1 适用: 人, 大鼠, 小鼠 IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-NMDA Receptor 1 (NMDA R1) antibodyNMDA R1 适用: 人, 大鼠, 小鼠 WB, IHC (p), IF, EIA 宿主: 兔 Polyclonal unconjugated
anti-NMDA Receptor 1 (NMDA R1) (pSer896) antibodyNMDA R1 适用: 人, 大鼠, 小鼠 IHC (p) 宿主: 兔 Polyclonal unconjugated
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- 应用备注
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Western Blot: 1/1,000. Immunoprecipitation: 3 μg per 200 μg lysate.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. - 限制
- 仅限研究用
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- 溶解方式
- Restore in 50 μL PBS (137 mM NaCl, 7.5 mM Na2HPO4, 2.7 mM KCl, 1.5 mM KH2PO4, pH 7.4) before use.
- 储存条件
- -20 °C
- 储存方法
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After reconstitution Store the antibody in aliquots at -20 °C. Avoid repeated freezing and thawing.
Shelf life: one year from despatch. - 有效期
- 12 months
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: "Moderate prenatal alcohol exposure reduces plasticity and alters NMDA receptor subunit composition in the dentate gyrus." in: The Journal of neuroscience : the official journal of the Society for Neuroscience, Vol. 33, Issue 3, pp. 1062-7, (2013) (PubMed).
: "Alcohol inhibition of the NMDA receptor function, long-term potentiation, and fear learning requires striatal-enriched protein tyrosine phosphatase." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 108, Issue 16, pp. 6650-5, (2011) (PubMed).
: "Long term synaptic depression that is associated with GluR1 dephosphorylation but not alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA) receptor internalization." in: The Journal of biological chemistry, Vol. 283, Issue 48, pp. 33138-46, (2008) (PubMed).
: "Altered NMDA receptor trafficking in a yeast artificial chromosome transgenic mouse model of Huntington's disease." in: The Journal of neuroscience : the official journal of the Society for Neuroscience, Vol. 27, Issue 14, pp. 3768-79, (2007) (PubMed).
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: "Moderate prenatal alcohol exposure reduces plasticity and alters NMDA receptor subunit composition in the dentate gyrus." in: The Journal of neuroscience : the official journal of the Society for Neuroscience, Vol. 33, Issue 3, pp. 1062-7, (2013) (PubMed).
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- 抗原
- NMDA 1 Receptor (NMDA R1) (NMDA Receptor 1 (NMDA R1))
- 别名
- NMDA Receptor 1 (NMDA R1 产品)
- 别名
- CG2902 antibody, DMNMDAR1 antibody, DNMDAR-I antibody, DNmdar antibody, DmelNmdar1 antibody, Dmel\\CG2902 antibody, DrNR1 antibody, NMDA antibody, NMDA R1 antibody, NMDAR1 antibody, NMdar1 antibody, NR1 antibody, NRI antibody, Nmdar antibody, dNR1 antibody, dnmdar-I antibody, nmr antibody, NMDA receptor 1 antibody, Nmdar1 antibody
- 背景
- The ion channels activated by glutamate are typically divided into two classes. Glutamate receptors that are activated by kainate and α-amino-3-hydroxy-5-methyl-4-isoxalone propionic acid (AMPA) are known as kainate/AMPA receptors (K/AMPAR). Those that are sensitive to N-methyl-D-aspartate (NMDA) are designated NMDA receptors (NMDAR). The NMDAR plays an essential role in memory, neuronal development and it has also been implicated in several disorders of the central nervous system including Alzheimer's, epilepsy and ischemic neuronal cell death (Grosshans et al., 2002, Wenthold et al., 2003, Carroll and Zukin, 2002). The NMDA receptor is also one of the principal molecular targets for alcohol in the CNS (Lovinger et al., 1989, Alvestad et al., 2003, Snell et al., 1996). The NMDAR is also potentiated by protein phosphorylation (Lu et al., 1999). The rat NMDAR1 (NR1) was the first subunit of the NMDAR to be cloned. The NR1 protein can form NMDA activated channels when expressed in Xenopus oocytes but the currents in such channels are much smaller than those seen in situ. Channels with more physiological characteristics are produced when the NR1-subunit is combined with one or more of the NMDAR2 (NR2 A-D) subunits.Synonyms: GRIN1, Glutamate [NMDA] receptor subunit zeta-1, NMDAR1
- 基因ID
- 24408
- UniProt
- P35439
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