NMDA 1 Receptor 抗体 (Splice Variant C2)
(2 references)-
- 抗原 See all NMDA 1 Receptor (NMDA R1) 抗体
- NMDA 1 Receptor (NMDA R1) (NMDA Receptor 1 (NMDA R1))
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抗原表位
- Splice Variant C2
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适用
- 人, 大鼠, 小鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This NMDA 1 Receptor antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunohistochemistry (Frozen Sections) (IHC (fro))
- 特异性
- This antibody recognizes the ~120k NR1 subunit of the NMDA Receptor containing the C2 splice variant insert. Does not recognize the NR1 subunits of the NMDA receptor that do not contain the C2 insert.
- 交叉反应 （详细）
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Species reactivity (expected):Human.
Species reactivity (tested):Mouse and Rat. - 纯化方法
- Affinity Chromatography.
- 免疫原
- Peptide from the NR1 subunit, C2 splice variant insert of Rat NMDA Receptor.
- 亚型
- IgG
- Top Product
- Discover our top product NMDA R1 Primary Antibody
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anti-NMDA Receptor 1 (NMDA R1) (AA 35-53) antibody
NMDA R1 适用: 人, 大鼠, 小鼠 WB, ELISA, IP 宿主: 兔 Polyclonal unconjugated
anti-NMDA Receptor 1 (NMDA R1) (AA 35-53) antibodyNMDA R1 适用: 人, 大鼠, 小鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-NMDA Receptor 1 (NMDA R1) (AA 1-564), (N-Term) antibodyNMDA R1 适用: 大鼠, 小鼠 WB, IHC (fro), IP 宿主: 小鼠 Monoclonal R1JHL unconjugated
anti-NMDA Receptor 1 (NMDA R1) (Splice Variant C2') antibodyNMDA R1 适用: 人, 大鼠, 小鼠, Cow WB, IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-NMDA Receptor 1 (NMDA R1) (AA 894-898) antibodyNMDA R1 适用: 人, 小鼠 WB 宿主: 兔 Polyclonal unconjugated
anti-NMDA Receptor 1 (NMDA R1) (pSer896) antibodyNMDA R1 适用: 人, 小鼠 WB 宿主: 兔 Polyclonal unconjugated
anti-NMDA Receptor 1 (NMDA R1) (AA 895-899) antibodyNMDA R1 适用: 人, 大鼠, 小鼠 IF 宿主: 兔 Polyclonal unconjugated
anti-NMDA Receptor 1 (NMDA R1) (pSer897) antibodyNMDA R1 适用: 人, 大鼠, 小鼠 IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-NMDA Receptor 1 (NMDA R1) antibodyNMDA R1 适用: 人, 大鼠, 小鼠 WB, IHC (p), IF, EIA 宿主: 兔 Polyclonal unconjugated
anti-NMDA Receptor 1 (NMDA R1) (pSer896) antibodyNMDA R1 适用: 人, 大鼠, 小鼠 IHC (p) 宿主: 兔 Polyclonal unconjugated
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- 应用备注
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Western blot: 1/1000. Immunohistochemistry on Frozen Sections: 1/1000-1/2000.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. - 限制
- 仅限研究用
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- 溶解方式
- Restore in 50 μL PBS (137 mM NaCl, 7.5 mM Na2HPO4, 2.7 mM KCl, 1.5 mM KH2PO4, pH 7.4) before use.
- 缓冲液
- 5 mM Ammonium Bicarbonate.
- 注意事项
- Avoid repeated freezing and thawing.
- 储存条件
- -20 °C
- 储存方法
- Store the antibody undiluted (in aliquots) at-20 °C.
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: "Moderate prenatal alcohol exposure reduces plasticity and alters NMDA receptor subunit composition in the dentate gyrus." in: The Journal of neuroscience : the official journal of the Society for Neuroscience, Vol. 33, Issue 3, pp. 1062-7, (2013) (PubMed).
: "LTP leads to rapid surface expression of NMDA but not AMPA receptors in adult rat CA1." in: Nature neuroscience, Vol. 5, Issue 1, pp. 27-33, (2001) (PubMed).
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: "Moderate prenatal alcohol exposure reduces plasticity and alters NMDA receptor subunit composition in the dentate gyrus." in: The Journal of neuroscience : the official journal of the Society for Neuroscience, Vol. 33, Issue 3, pp. 1062-7, (2013) (PubMed).
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- 抗原
- NMDA 1 Receptor (NMDA R1) (NMDA Receptor 1 (NMDA R1))
- 别名
- NMDA Receptor 1 (NMDA R1 产品)
- 别名
- CG2902 antibody, DMNMDAR1 antibody, DNMDAR-I antibody, DNmdar antibody, DmelNmdar1 antibody, Dmel\\CG2902 antibody, DrNR1 antibody, NMDA antibody, NMDA R1 antibody, NMDAR1 antibody, NMdar1 antibody, NR1 antibody, NRI antibody, Nmdar antibody, dNR1 antibody, dnmdar-I antibody, nmr antibody, NMDA receptor 1 antibody, Nmdar1 antibody
- 背景
- The ion channels activated by glutamate that are sensitive to N-methyl-D-aspartate (NMDA) are designated NMDA Receptors (NMDAR). The NMDAR plays an essential role in memory, neuronal development and it has also been implicated in several disorders of the central nervous system including Alzheimer's, epilepsy and ischemic neuronal cell death (Grosshans et al., 2002, Wenthold et al., 2003, Carroll and Zukin, 2002). There are a number of different splice variants of the NR1 subunit (Foldes et al., 1994, Zukin and Bennett, 1995). Differential splicing of three exons in the NR1 subunit generates up to eight NR1 subunit splice variants and 7 of these have been identified in cDNA libraries. These exons encode a 21 amino acid N-terminal domain (N1) and adjacent sequences in the C-terminus (C1 and C2). Splicing out the C2 cassette eliminates the first stop codon and produces a new reading frame that generates a new sequence of 22 amino acids (C2'). Considerable attention has been focused on the distribution and expression of these splice variants that may affect the functional properties and regulation of the NMDAR.Synonyms: GRIN1, Glutamate [NMDA] receptor subunit zeta-1, NMDAR1
- 基因ID
- 24408
- NCBI登录号
- NP_058706
- UniProt
- P35439
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