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IL1R1 抗体 (Extracellular Domain)

IL1R1 适用: 人 ELISA, IHC, IHC (p), RIA 宿主: 小鼠 Monoclonal 40101 unconjugated
产品编号 ABIN364253
发货至: 中国
  • 抗原 See all IL1R1 抗体
    IL1R1 (Interleukin 1 Receptor, Type I (IL1R1))
    抗原表位
    • 28
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    Extracellular Domain
    适用
    • 119
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    宿主
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    小鼠
    克隆类型
    • 120
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    单克隆
    标记
    • 59
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    This IL1R1 antibody is un-conjugated
    应用范围
    • 122
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    ELISA, Immunohistochemistry (IHC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Radioimmunoassay (RIA)
    品牌
    IHC-plus™
    特异性
    These antibodies react with cell surface and soluble human IL-1 receptor, Specific epitopes are unknown, but they do partially inhibit (30-50 % ) binding of one another to IL-1 receptor. They do not block binding of IL-1 to receptor, and they do not cross-react with receptors for human IL-2 or IL-4.
    纯化方法
    Protein G purified
    免疫原
    The extracellular domain of the type I human IL-1 receptor.

    Type of Immunogen: Protein
    克隆位点
    40101
    亚型
    IgG2b
    Top Product
    Discover our top product IL1R1 Primary Antibody
  • 应用备注
    Approved: ELISA, IHC, IHC-P (10 μg/mL), RIA

    Usage: Immunohistochemistry: This antibody was validated for use in immunohistochemistry on a panel of 21 formalin-fixed, paraffin-embedded (FFPE) human tissues after heat induced antigen retrieval in  pH 6.0 citrate buffer. After incubation with the primary antibody, slides were incubated with biotinylated secondary antibody, followed by alkaline phosphatase-streptavidin and chromogen. The stained slides were evaluated by a pathologist to confirm staining specificity. The optimal working concentration for this antibody was determined to be 10 μg/mL. ELISA: Can be used as capture reagents or second antibody at a concentration of 5 μg/mL. RIA: Concentrations of 20-30 ng/mL of these antibodies will bind radiolabeled IL-1 receptor in a radioimmunoassay format. Immunocytochemistry: IL-1 receptor can be detected on cultured cells using antibody concentrations of 10-100 μg/mL.

    Not recommended for: WB
    说明

    Target Species of Antibody: Human

    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    Lot specific
    缓冲液
    PBS,  pH 7.4. Sourced in Ascites.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    -20 °C,-80 °C
    储存方法
    Short term: -20°C
    Long term: -70°C
    Avoid freeze-thaw cycles.
  • 抗原
    IL1R1 (Interleukin 1 Receptor, Type I (IL1R1))
    别名
    IL1RA / IL1R1 (IL1R1 产品)
    别名
    CD121A antibody, D2S1473 antibody, IL-1R-alpha antibody, IL1R antibody, IL1RA antibody, P80 antibody, CD121a antibody, CD121b antibody, IL-iR antibody, Il1r-1 antibody, DER4 antibody, Fit-1 antibody, Ly84 antibody, ST2L antibody, St2 antibody, St2-rs1 antibody, T1 antibody, T1/ST2 antibody, interleukin 1 receptor type 1 antibody, interleukin 1 receptor, type I antibody, interleukin 1 receptor-like 1 antibody, IL1R1 antibody, Il1r1 antibody, Il1rl1 antibody
    背景
    Name/Gene ID: IL1R1
    Family: Interleukin

    Synonyms: IL1R1, Antigen CD121a, D2S1473, IL-1R-1, IL-1R-alpha, IL-1RT-1, IL-1RT1, IL1R, IL1RA, IL1RT1, Interleukin receptor 1, Interleukin-1 receptor alpha, Interleukin-1 receptor type 1, CD121A, CD121a antigen, Interleukin 1 receptor, type I, Interleukin-1 receptor type I, Interleukin-1 type i receptor, p80
    基因ID
    3554
    UniProt
    P14778
    途径
    NF-kappaB Signaling, Carbohydrate Homeostasis, Cancer Immune Checkpoints
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