电话:
+86 (0512) 65829739
传真:
+86 (010) 6788 5057
电子邮件:
orders@antibodies-online.cn

MAP2K3 抗体 (AA 187-191)

This anti-MAP2K3 antibody is a 兔 多克隆 antibody detecting MAP2K3 in WB, IHC 和 IF. Suitable for 人 和 大鼠.
产品编号 ABIN362698
发货至: 中国

Quick Overview for MAP2K3 抗体 (AA 187-191) (ABIN362698)

抗原

See all MAP2K3 抗体
MAP2K3 (Mitogen-Activated Protein Kinase Kinase 3 (MAP2K3))

适用

  • 131
  • 101
  • 78
  • 11
  • 10
  • 6
  • 5
  • 5
  • 4
  • 3
  • 1
  • 1
  • 1
  • 1
人, 大鼠

宿主

  • 136
  • 11

克隆类型

  • 126
  • 21
多克隆

标记

  • 71
  • 8
  • 6
  • 5
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 2
  • 2
  • 1
  • 1
This MAP2K3 antibody is un-conjugated

应用范围

  • 117
  • 46
  • 40
  • 39
  • 38
  • 24
  • 22
  • 11
  • 10
  • 9
  • 5
  • 2
  • 1
  • 1
  • 1
Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)
  • 抗原表位

    • 26
    • 15
    • 15
    • 11
    • 10
    • 8
    • 7
    • 6
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 187-191

    特异性

    The antibody detects endogenous level of total MKK3 protein.

    纯化方法

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography usingepitope-specific immunogen.

    免疫原

    Peptide sequence around AA 187-191 (V-D-S-V-A) derived from Human MKK3. Antibodies were produced by immunizing rabbits with synthetic peptide and KLH conjugates.

    亚型

    IgG
  • 应用备注

    Western blotting: 1:500-1:1000
    Immunohistochemistry: 1:50-1:100
    Immunofluorescence: 1:100-1:200

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    Phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C/-20 °C

    储存方法

    Store at -20 °C for long term preservation (recommended). Store at 4 °C for short term use.
  • 抗原

    MAP2K3 (Mitogen-Activated Protein Kinase Kinase 3 (MAP2K3))

    别名

    MKK3

    背景

    MEK3 belongs to MAPKK family. This kinase is activated by mitogenic and environmental stress, and participates in the MAPK-mediated signaling cascade. It phosphorylates and thus activates p38. This kinase can be activated by insulin, and is necessary for the expression of glucose transporter. Expression of Ras oncogene is found to result in the accumulation of the active form of this kinase, which thus leads to the constitutive activation of p38, and confers oncogenic transformation of primary cells. The inhibition of this kinase is involved in the pathogenesis of Yersina pseudotuberculosis.

    分子量

    40 kDa

    NCBI登录号

    NP_002747

    UniProt

    P46734

    途径

    MAPK Pathway, TLR signaling, Activation of Innate immune Response, Toll-Like Receptors Cascades, Autophagy, Signaling Events mediated by VEGFR1 and VEGFR2
You are here:
Chat with us!