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Periostin 抗体

POSTN 适用: 小鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN361362
发货至: 中国
  • 抗原 See all Periostin (POSTN) 抗体
    Periostin (POSTN)
    适用
    • 80
    • 39
    • 26
    • 6
    • 4
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    小鼠
    宿主
    • 79
    • 16
    • 3
    • 2
    • 2
    克隆类型
    • 73
    • 29
    多克隆
    标记
    • 55
    • 17
    • 9
    • 5
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    This Periostin antibody is un-conjugated
    应用范围
    • 74
    • 46
    • 36
    • 14
    • 14
    • 12
    • 6
    • 5
    • 4
    • 3
    • 2
    • 2
    • 2
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC)
    特异性
    The antibody has been directly tested for reactivity in chicken, human, mouse and rat. Based on the homology of the immunogen with other species, we expect that this antibody will recognize periostin in most, if not all, species of mammals, birds, amphibians, and fishes. Specific for three periostin bands around ~93 kDa in mouse lung extract. The immunogenic peptide is present in all known splice variants of periostin and therefore this antibody recognizes all known molecular forms of periostin. The antibody also works well for immunohistochemistry on paraformaldehyde-fixed sections with a simple antigenretrieval protocol (incubate slides for 20 minutes at 90° C in 10 mM sodium citrate (pH 6.0)/ 0.1 % Tween-20).
    交叉反应
    小鸡, 人, 小鼠
    预测反应
    most mammalian, avian, amphibian and fishes
    纯化方法
    Antigen Affinity Purified
    免疫原
    Synthetic peptide corresponding to amino acid residues from the fasciclin domain 1 of mouse periostin
    Top Product
    Discover our top product POSTN Primary Antibody
  • 应用备注
    Recommended Dilution: WB: 1:1,000 IHC: 1:100 Quality Control: Western blots performed on each lot.
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    ~ 0.5 mg/ml
    缓冲液
    100 μL in PBS
    储存条件
    -20 °C
  • 抗原
    Periostin (POSTN)
    别名
    POSTN (POSTN 产品)
    别名
    fa99h07 antibody, pn antibody, postn antibody, wu:fa99h07 antibody, wu:fc70f09 antibody, zgc:153873 antibody, LOC100008945 antibody, osf-2 antibody, pdlpostn antibody, periostin antibody, OSF-2 antibody, OSF2 antibody, PDLPOSTN antibody, PN antibody, RP11-412K4.1 antibody, A630052E07Rik antibody, AI747096 antibody, Osf2 antibody, PLF antibody, peri antibody, Plf antibody, periostin antibody, periostin, osteoblast specific factor b antibody, periostin, osteoblast specific factor antibody, POSTN antibody, postnb antibody, postn antibody, Postn antibody
    背景
    Periostin is a matricellular protein, i.e. an extracellular matrix protein that interacts both with other ECM proteins and with cell-surface receptors. Like many other matricellular proteins, the function of periostin is important both in embryonic development and in the remodeling of adult tissues in response to pathological insults. Periostin was originally isolated as an osteoblast-specific marker that functions as a cell adhesion molecule for preosteoblasts and is thought to be involved in osteoblast recruitment, attachment and spreading (Kruzynska-Frejtag A. et al., 2004). Periostin has recently been shown to promote collagen fibrogenesis, inhibit differentiation of progenitor cells into cardiomyocytes and to be essential in maintaining the biomechanical properties of the adult myocardium (Norris et al., 2008).
    分子量
    '93 kDa
    基因ID
    50706
    UniProt
    Q62009
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