Periostin 抗体 (AA 193-326)
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- 抗原 See all Periostin (POSTN) 抗体
- Periostin (POSTN)
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抗原表位
- AA 193-326
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适用
- 人
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This Periostin antibody is un-conjugated
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应用范围
- Immunohistochemistry (Formalin-fixed Sections) (IHC (f))
- 特异性
- Periostin (PN), also designated osteoblast-specific factor 2 (OSF-2), is a disulfide linked protein originally isolated as a osteoblast-specific factor. Periostin is a secreted protein that binds heparin and functions as a ligand for i±Vi²3 and i±Vi²5 integrins. In preosteoblasts, Periostin acts as a cell adhesion molecule and plays a role in osteoblast recruitment, spreading and attachment. Periostin is mainly detected in lower gastrointestinal tract, aorta, stomach, placenta, uterus and breast tissues but is up-regulated in epithelial ovarian tumors and overexpressed in breast cancer. Expression of Periostin is increased by bone morphogenetic protein (BMP2) and transforming growth factor i² 1 (TGF i² 1). Periostin contains a typical signal sequence, followed by a cysteine-rich domain, a fourfold repeated domain, which shows homology with the insect protein fasciclin, and a C-terminal domain.
- 交叉反应 （详细）
- Human.
- 纯化方法
- 200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G.
- 免疫原
- Recombinant fragment (around aa193-326) of human POSTN protein (exact sequence is proprietary)
- 亚型
- IgG2b
- Top Product
- Discover our top product POSTN Primary Antibody
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anti-Periostin (POSTN) (C-Term) antibody
POSTN 适用: 人 WB, ICC, IF, IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Periostin (POSTN) (AA 97-230) antibodyPOSTN 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Periostin (POSTN) (AA 577-810) antibodyPOSTN 适用: 小鼠, 大鼠 WB, ELISA, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Periostin (POSTN) (AA 687-716), (C-Term) antibodyPOSTN 适用: 人, 大鼠 WB, IF, IHC (p), FACS 宿主: 兔 Polyclonal RB18585 unconjugated
anti-Periostin (POSTN) (Middle Region) antibodyPOSTN 适用: 人, 小鼠, 大鼠, 豚鼠, Cow, 犬, 马, 兔, Pig WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Periostin (POSTN) (AA 24-836) antibodyPOSTN 适用: 人 WB, IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Periostin (POSTN) (AA 193-326) antibodyPOSTN 适用: 人 IHC (f) 宿主: 小鼠 Monoclonal unconjugated
anti-Periostin (POSTN) (AA 24-173) antibodyPOSTN 适用: 大鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Periostin (POSTN) (AA 193-326) antibodyPOSTN 适用: 人 IHC 宿主: 小鼠 Monoclonal MSVA-649M unconjugated
anti-Periostin (POSTN) (AA 370-494) antibodyPOSTN 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
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- 应用备注
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Positive Control: Human placenta, breast or colon tissue.
Known Application: Immunohistochemistry (Formalin-fixed) (1-2 μg/mL for 30 minutes at RT),(Staining of formalin-fixed tissues requires heating tissue sections in 10 mM Tris with 1 mM EDTA, pH 9.0, for 45 min at 95 °C followed by cooling at RT for 20 minutes),Optimal dilution for a specific application should be determined.
- 限制
- 仅限研究用
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- 浓度
- 200 μg/mL
- 缓冲液
- Prepared in 10 mM PBS with 0.05 % BSA and 0.05 % azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C,-80 °C
- 储存方法
- Antibody with azide - store at 2 to 8 °C. Antibody is stable for 24 months. Non-hazardous. Also available WITHOUT BSA & azide at 1.0mg/ml.
- 有效期
- 24 months
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- 抗原
- Periostin (POSTN)
- 别名
- POSTN (POSTN 产品)
- 别名
- fa99h07 antibody, pn antibody, postn antibody, wu:fa99h07 antibody, wu:fc70f09 antibody, zgc:153873 antibody, LOC100008945 antibody, osf-2 antibody, pdlpostn antibody, periostin antibody, OSF-2 antibody, OSF2 antibody, PDLPOSTN antibody, PN antibody, RP11-412K4.1 antibody, A630052E07Rik antibody, AI747096 antibody, Osf2 antibody, PLF antibody, peri antibody, Plf antibody, periostin antibody, periostin, osteoblast specific factor b antibody, periostin, osteoblast specific factor antibody, POSTN antibody, postnb antibody, postn antibody, Postn antibody
- 背景
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Fasciclin-I like, Osteoblast specific factor 2 (OSF2), PDLPOSTN, Periodontal ligament specific periostin, Periostin isoform thy2 / th4 / thy6 / thy8, Periostin osteoblast specific factor, PN, POSTN,Periostin (POSTN)
Cellular localisation: Secreted > extracellular space > extracellular matrix. - 分子量
- 84/74kDa (Periostin), 90kDa (secreted glycoprotein)
- 基因ID
- 10631, 136348, 721018
- UniProt
- Q15063
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