HRAS 抗体 (Middle Region)
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Quick Overview for HRAS 抗体 (Middle Region) (ABIN360066)
抗原
See all HRAS 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- Middle Region
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特异性
- This antibody reacts to HRAS.
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纯化方法
- Prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS
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免疫原
- This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the Center region of human HRAS.
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亚型
- Ig Fraction
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anti-HRas proto-oncogene, GTPase (HRAS) (C-Term) antibody
HRAS 适用: 人, 小鼠, 大鼠 WB, IF, ICC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-HRas proto-oncogene, GTPase (HRAS) (AA 50-100) antibodyHRAS 适用: 人, 小鼠 WB, FACS 宿主: 兔 Monoclonal BLR321M unconjugated Recombinant Antibody
anti-HRas proto-oncogene, GTPase (HRAS) antibodyHRAS 适用: 人, 小鼠, 大鼠, 犬, 猴 WB, IHC, IF, IHC (p) 宿主: 小鼠 Monoclonal 1C2 unconjugated
anti-HRas proto-oncogene, GTPase (HRAS) (AA 50-100) antibodyHRAS 适用: 人 WB, IHC, IP, ICC, FACS 宿主: 兔 Monoclonal BLR326M unconjugated Recombinant Antibody
anti-HRas proto-oncogene, GTPase (HRAS) (AA 104-128) antibodyHRAS 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-HRas proto-oncogene, GTPase (HRAS) antibodyHRAS 适用: 人, 小鼠, 大鼠, 犬, 猴 WB, IHC, IF, IHC (p) 宿主: 小鼠 Monoclonal 1A1 unconjugated
anti-HRas proto-oncogene, GTPase (HRAS) antibodyKD Validated HRAS 适用: 人 WB, ICC, FACS 宿主: 兔 Monoclonal 23GB6035 unconjugated Recombinant Antibody
anti-HRas proto-oncogene, GTPase (HRAS) (AA 50-100) antibodyHRAS 适用: 人, 小鼠 WB 宿主: 兔 Monoclonal BLR341M unconjugated Recombinant Antibody
anti-HRas proto-oncogene, GTPase (HRAS) (AA 104-128) antibodyHRAS 适用: 人 WB, IF, IHC (p) 宿主: 兔 Polyclonal RB15622 unconjugated
anti-HRas proto-oncogene, GTPase (HRAS) (AA 146-176) antibodyHRAS 适用: 人, 小鼠 WB, ELISA, IF 宿主: 兔 Polyclonal unconjugated
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应用备注
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ELISA: 1/1,000. Western blotting: 1/50 - 1/100.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.25 mg/mL
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缓冲液
- PBS with 0.09 % (W/V) sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.
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- HRAS (HRas proto-oncogene, GTPase (HRAS))
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别名
- HRAS
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背景
- HRAS belongs to the Ras oncogene family, whose members are related to the transforming genes of mammalian sarcoma retroviruses. These proteins function in signal transduction pathways. They can bind GTP and GDP, and they have intrinsic GTPase activity. HRAS undergoes a continuous cycle of de- and re-palmitoylation, which regulates its rapid exchange between the plasma membrane and the Golgi apparatus. Mutations in this gene cause Costello syndrome, a disease characterized by increased growth at the prenatal stage, growth deficiency at the postnatal stage, predisposition to tumor formation, mental retardation, skin and musculoskeletal abnormalities, distinctive facial appearance and cardiovascular abnormalities. Defects in the HRAS gene are implicated in a variety of cancers, including bladder cancer, follicular thyroid cancer, and oral squamous cell carcinoma.Synonyms: GTPase HRas, H-Ras, H-Ras-1, HRAS1, Ha-Ras, c-H-ras, p21ras, v-Ha-ras Harvey rat sarcoma viral oncogene homolog
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基因ID
- 3265, 9606
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UniProt
- P01112
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途径
- p53 Pathway, MAPK Pathway, RTK signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Hepatitis C, Autophagy, Signaling Events mediated by VEGFR1 and VEGFR2, Signaling of Hepatocyte Growth Factor Receptor, Regulation of long-term Neuronal Synaptic Plasticity, VEGF Signaling, BCR Signaling
抗原
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