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ACVR2B 抗体 (N-Term)

ACVR2B 适用: 人 WB, IHC (p), EIA 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN359230
发货至: 中国
  • 抗原 See all ACVR2B 抗体
    ACVR2B (Activin A Receptor, Type IIB (ACVR2B))
    抗原表位
    • 15
    • 9
    • 7
    • 7
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    • 7
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    • 1
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    • 1
    N-Term
    适用
    • 72
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    宿主
    • 70
    • 7
    • 3
    克隆类型
    • 75
    • 5
    多克隆
    标记
    • 37
    • 12
    • 5
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    • 1
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    This ACVR2B antibody is un-conjugated
    应用范围
    • 75
    • 28
    • 23
    • 13
    • 13
    • 7
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
    特异性
    This antibody recognizes ACVR2B.
    交叉反应 (详细)
    Species reactivity (tested):Human.
    纯化方法
    Prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS
    免疫原
    This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the N-terminal region of human ACVR2B.
    亚型
    Ig Fraction
    Top Product
    Discover our top product ACVR2B Primary Antibody
  • 应用备注
    ELISA: 1/1,000. Western blotting.1/100-1/500. Immunohistochemistry: 1/50-1/100.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    0.25 mg/mL
    缓冲液
    PBS with 0.09 % (W/V) Sodium Azide as preservative.
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    4 °C/-20 °C
    储存方法
    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.
  • 抗原
    ACVR2B (Activin A Receptor, Type IIB (ACVR2B))
    别名
    Activin Receptor Type 2B (ACVR2B) (ACVR2B 产品)
    别名
    ACVR2B antibody, XAR1 antibody, actr-iib antibody, actriib antibody, ACTRIIB antibody, ActR-IIB antibody, HTX4 antibody, ActRIIB antibody, actr2b antibody, actrIIb antibody, wu:fj97d11 antibody, activin A receptor type 2B antibody, activin A receptor type 2B L homeolog antibody, activin A receptor type 2Ba antibody, activin receptor IIB antibody, ACVR2B antibody, acvr2b antibody, acvr2b.L antibody, Acvr2b antibody, acvr2ba antibody
    背景
    Activins are dimeric growth and differentiation factors which belong to the transforming growth factor-beta (TGF-beta) superfamily of structurally related signaling proteins. Activins signal through a heteromeric complex of receptor serine kinases which include at least two type I (I and IB) and two type II (II and IIB) receptors. These receptors are all transmembrane proteins, composed of a ligand-binding extracellular domain with cysteine-rich region, a transmembrane domain, and a cytoplasmic domain with predicted serine/threonine specificity. Type I receptors are essential for signaling, and type II receptors are required for binding ligands and for expression of type I receptors. Type I and II receptors form a stable complex after ligand binding, resulting in phosphorylation of type I receptors by type II receptors. Type II receptors are considered to be constitutively active kinases. ACVR2B (activin A type IIB receptor) displays a 3- to 4-fold higher affinity for the ligand than activin A type II receptor.Synonyms: ACTR-IIB, ACTRIIB, Activin receptor type IIB
    分子量
    57639 Da
    基因ID
    93, 9606
    UniProt
    Q13705
    途径
    Hormone Transport, Cancer Immune Checkpoints
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