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CD45 抗体 (C-Term)

Name: CD45 抗体 (C-Term)
SKU: ABIN357138
Availability: OutOfStock

PTPRC 适用: 人 FACS, WB, IHC (p), EIA 宿主: 兔 Polyclonal unconjugated

Image no. 2 for anti-Protein tyrosine Phosphatase, Receptor Type, C (PTPRC) (AA 1252-1282), (C-Term) antibody (ABIN357138) (CD45 抗体 (C-Term))

Image no. 1 for anti-Protein tyrosine Phosphatase, Receptor Type, C (PTPRC) (AA 1252-1282), (C-Term) antibody (ABIN357138) (CD45 抗体 (C-Term))

Image no. 3 for anti-Protein tyrosine Phosphatase, Receptor Type, C (PTPRC) (AA 1252-1282), (C-Term) antibody (ABIN357138) (CD45 抗体 (C-Term))

3 images

产品编号 ABIN357138

发货至: 中国

Datasheet as PDF

抗原 See all CD45 (PTPRC) 抗体

CD45 (PTPRC) (Protein tyrosine Phosphatase, Receptor Type, C (PTPRC))
抗原表位
16

16

14

13

13

10

9

7

6

6

3

3

2

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1
AA 1252-1282, C-Term
适用
384

227

79

29

20

16

15

10

7

6

6

4

4

3

3

3

2

1

1

1

1

1

1
人
宿主
282

178

138

2

1

1
兔
Compatible Secondaries
克隆类型
467

127

1
多克隆
标记
174

58

49

46

38

15

13

11

10

10

9

9

8

8

7

6

6

6

6

6

5

5

5

4

4

4

4

4

4

4

4

4

4

4

3

3

3

3

3

3

2

2

2

2

2

2

1

1

1

1

1
This CD45 antibody is un-conjugated
应用范围
495

197

148

127

126

74

59

57

47

27

17

15

14

13

12

5

4

3

3

3

2

1

1

1

1

1

1

1
Flow Cytometry (FACS), Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

特异性

This antibody detects CD45 at C-term.

交叉反应（详细）

Species reactivity (tested):Human.

纯化方法

Protein G Chromatography, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS

免疫原

KLH conjugated synthetic peptide between 1252~1282 amino acids from the C-terminal region of Human CD45. Genename: PTPRC

亚型

Ig Fraction

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anti-Protein tyrosine Phosphatase, Receptor Type, C (PTPRC) antibody
PTPRC 适用: 人, 犬 FACS, IHC, WB, StM 宿主: 小鼠 Monoclonal 2B11-PD7-26 unconjugated

anti-Protein tyrosine Phosphatase, Receptor Type, C (PTPRC) (AA 193-575) antibody
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anti-Protein tyrosine Phosphatase, Receptor Type, C (PTPRC) (AA 371-556) antibody
PTPRC 适用: 小鼠 IHC, WB, IP, ICC 宿主: 兔 Polyclonal unconjugated

anti-Protein tyrosine Phosphatase, Receptor Type, C (PTPRC) (AA 24-575) antibody
PTPRC 适用: 人 FACS, IHC, WB, IF, ELISA 宿主: 小鼠 Monoclonal 17H9D4 unconjugated

anti-Protein tyrosine Phosphatase, Receptor Type, C (PTPRC) (C-Term) antibody
PTPRC 适用: 人, 小鼠, 大鼠, 犬, 小鸡, Cow, Cat, 兔, 绵羊, Pig, 豚鼠, 山羊, 马, 猴, Avian, 驴, Hamster WB 宿主: 山羊 Polyclonal unconjugated

anti-Protein tyrosine Phosphatase, Receptor Type, C (PTPRC) antibody
PTPRC 适用: 人 FACS, IHC, WB, IF, StM 宿主: 兔 Monoclonal PTPRC-2877R unconjugated Recombinant Antibody

anti-Protein tyrosine Phosphatase, Receptor Type, C (PTPRC) antibody
PTPRC 适用: 人 FACS, WB, IP, IHC (p), ICC 宿主: 小鼠 Monoclonal MEM-28 unconjugated

anti-Protein tyrosine Phosphatase, Receptor Type, C (PTPRC) (AA 378-577) antibody
PTPRC 适用: 人, 小鼠, 大鼠 FACS, IHC, WB, ELISA, ICC 宿主: 小鼠 Monoclonal 2H3E2 unconjugated

anti-Protein tyrosine Phosphatase, Receptor Type, C (PTPRC) (AA 431-577) antibody
PTPRC 适用: 人 FACS, IHC, WB, ELISA, ICC, Neut 宿主: 小鼠 Monoclonal 7C9F12 unconjugated

应用备注

ELISA: 1/1,000. Western blot: 1/100-1/500.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

限制

仅限研究用
状态

Liquid

浓度

0.25 mg/mL

缓冲液

PBS with 0.09 % (W/V) Sodium Azide as preservative.

储存液

Sodium azide

注意事项

This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

注意事项

Avoid repeated freezing and thawing.

储存条件

4 °C/-20 °C

储存方法

Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.
抗原

CD45 (PTPRC) (Protein tyrosine Phosphatase, Receptor Type, C (PTPRC))

别名

CD45 / LCA (PTPRC 产品)

别名

PTPRC antibody, si:dkeyp-47c5.1 antibody, B220 antibody, CD45 antibody, CD45R antibody, GP180 antibody, L-CA antibody, LCA antibody, LY5 antibody, T200 antibody, Cd45 antibody, Ly-5 antibody, Lyt-4 antibody, loc antibody, Lca antibody, RT7 antibody, cd45 antibody, protein tyrosine phosphatase, receptor type C antibody, protein tyrosine phosphatase, receptor type, C antibody, receptor-type tyrosine-protein phosphatase C antibody, PTPRC antibody, ptprc antibody, LOC100074271 antibody, Ptprc antibody

背景

CD45 is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP contains an extracellular domain, a single transmembrane segment and two tandem intracytoplasmic catalytic domains, and thus belongs to receptor type PTP. The CD45 gene is specifically expressed in hematopoietic cells. This PTP has been shown to be an essential regulator of T- and B-cell antigen receptor signaling. It functions through either direct interaction with components of the antigen receptor complexes, or by activating various Src family kinases required for the antigen receptor signaling. This PTP also suppresses JAK kinases, and thus functions as a regulator of cytokine receptor signaling.Synonyms: L-CA, Leukocyte common antigen, PTPRC, Receptor-type tyrosine-protein phosphatase C, T200

分子量

147253 Da

基因ID

5788, 9606

UniProt

P08575

途径

TCR Signaling, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, CXCR4-mediated Signaling Events, BCR Signaling