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Amylin/DAP 抗体

IAPP 适用: 人 WB, ELISA 宿主: 小鸡 Polyclonal unconjugated
产品编号 ABIN334637
发货至: 中国
  • 抗原 See all Amylin/DAP (IAPP) 抗体
    Amylin/DAP (IAPP) (Islet Amyloid Polypeptide (IAPP))
    适用
    • 48
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    宿主
    • 50
    • 3
    小鸡
    克隆类型
    • 50
    • 3
    多克隆
    标记
    • 31
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    This Amylin/DAP antibody is un-conjugated
    应用范围
    • 34
    • 18
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    Western Blotting (WB), ELISA
    产品特性
    Expected / apparent Molecular Weight of the Antigene: 4 kDa
    纯化方法
    affinity purified
    免疫原
    synthetic peptide based on human IAPP sequence: K-C-N-T-A-T-C-A-T-Q-R-L-A-N-F-L-V-H-S-S-N-N-F-G-A-I-L-S-S-T-N-V-G-S-N-T-Y
    亚型
    IgY
    Top Product
    Discover our top product IAPP Primary Antibody
  • 应用备注
    Recommended Dilution: 1 : 1000 (WB), 1 : 1000 (ELISA).
    说明

    antibody is recognizing trimer, dimer and monomer human IAPP

    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    PBS pH 8.0 + 0.02 % sodium azide
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Please, remember to spin tubes briefly prior to opening them to avoid any losses that might occur from liquid material adhering to the cap or sides of the tubes.
    Make aliquots to avoid repreated freeze-thaw cycles and working with a stock.
    储存条件
    4 °C
  • 抗原
    Amylin/DAP (IAPP) (Islet Amyloid Polypeptide (IAPP))
    别名
    IAPP (IAPP 产品)
    别名
    DAP antibody, IAP antibody, LOC100230121 antibody, Amylin antibody, islet amyloid polypeptide antibody, IAPP antibody, Iapp antibody
    背景
    Amylin, or Islet Amyloid Polypeptide (IAPP) P10997, is a 37-residue peptide hormone secreted by pancreatic beta-cells at the same time as insulin (in a roughly 1:100 amylin:insulin ratio). Islet, or insulinoma, almyloid polypeptide (IAPP, or amylin) is commonly found in pancreatic islets of patients suffering diabetes mellitus type 2, or harboring an insulinoma. While the association of amylin with the development of type 2 diabetes has been known for some time, a direct causative role for amylin has been harder to establish. Recent results suggest that amylin, like the related beta-amyloid (Abeta) associated with Alzherimer's disease, can induce apoptotic cell-death in particular cultured cells, an effect that may be relevant to the deleopment of type 2 diabetes.
    分子量
    4 kDa
    途径
    Hormone Activity, Feeding Behaviour
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