Amylin/DAP 抗体
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- 抗原 See all Amylin/DAP (IAPP) 抗体
- Amylin/DAP (IAPP) (Islet Amyloid Polypeptide (IAPP))
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适用
- 人
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宿主
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小鸡
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克隆类型
- 多克隆
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标记
- This Amylin/DAP antibody is un-conjugated
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应用范围
- Western Blotting (WB), ELISA
- 产品特性
- Expected / apparent Molecular Weight of the Antigene: 4 kDa
- 纯化方法
- affinity purified
- 免疫原
- synthetic peptide based on human IAPP sequence: K-C-N-T-A-T-C-A-T-Q-R-L-A-N-F-L-V-H-S-S-N-N-F-G-A-I-L-S-S-T-N-V-G-S-N-T-Y
- 亚型
- IgY
- Top Product
- Discover our top product IAPP Primary Antibody
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- 应用备注
- Recommended Dilution: 1 : 1000 (WB), 1 : 1000 (ELISA).
- 说明
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antibody is recognizing trimer, dimer and monomer human IAPP
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- PBS pH 8.0 + 0.02 % sodium azide
- 储存液
- Sodium azide
- 注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
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Please, remember to spin tubes briefly prior to opening them to avoid any losses that might occur from liquid material adhering to the cap or sides of the tubes.
Make aliquots to avoid repreated freeze-thaw cycles and working with a stock. - 储存条件
- 4 °C
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- 抗原
- Amylin/DAP (IAPP) (Islet Amyloid Polypeptide (IAPP))
- 别名
- IAPP (IAPP 产品)
- 别名
- DAP antibody, IAP antibody, LOC100230121 antibody, Amylin antibody, islet amyloid polypeptide antibody, IAPP antibody, Iapp antibody
- 背景
- Amylin, or Islet Amyloid Polypeptide (IAPP) P10997, is a 37-residue peptide hormone secreted by pancreatic beta-cells at the same time as insulin (in a roughly 1:100 amylin:insulin ratio). Islet, or insulinoma, almyloid polypeptide (IAPP, or amylin) is commonly found in pancreatic islets of patients suffering diabetes mellitus type 2, or harboring an insulinoma. While the association of amylin with the development of type 2 diabetes has been known for some time, a direct causative role for amylin has been harder to establish. Recent results suggest that amylin, like the related beta-amyloid (Abeta) associated with Alzherimer's disease, can induce apoptotic cell-death in particular cultured cells, an effect that may be relevant to the deleopment of type 2 diabetes.
- 分子量
- 4 kDa
- 途径
- Hormone Activity, Feeding Behaviour
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