IRF7 抗体 (C-Term)
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Quick Overview for IRF7 抗体 (C-Term) (ABIN318755)
抗原
See all IRF7 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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特异性
- This antibody detects an epitope within the C-terminal of Human Interferon Regulatory Factor 7 (IRF7).
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纯化方法
- Affinity Chromatography.
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免疫原
- 14 amino acid peptide sequence near the carboxy terminus of Human IRF7.
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亚型
- IgG
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应用备注
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Western Blot: 1.0-2.0 μg/mL. This antibody detects a band of approximately 51 kDa in 293 whole cell lysate.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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浓度
- 1.0 mg/mL
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缓冲液
- PBS containing 0.02 % Sodium Azide as preservative.
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- IRF7 (Interferon Regulatory Factor 7 (IRF7))
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别名
- IRF7
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背景
- IRF7 is a 54kD transcriptional activator of type I interferons (IFNalpha/beta) in response to local and systemic viral infection. IRF7 is mostly expressed by plasmacytoid dendritic cells (pDC), which differentiate in response to IFNs and virus infection. This then stabilizes the IRF7 protein, in turn leading to increased IFN production. Multiple IRF7 transcript variants have been identified, although their individual functions have not yet been established.Synonyms: IRF-7, Interferon regulatory factor 7
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基因ID
- 3665
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NCBI登录号
- NP_001563
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UniProt
- Q92985
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途径
- TLR signaling, Activation of Innate immune Response, Hepatitis C, Toll-Like Receptors Cascades, Autophagy
抗原
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