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IRF7 抗体 (C-Term)

This anti-IRF7 antibody is a 兔 多克隆 antibody detecting IRF7 in WB. Suitable for 人, 小鼠 和 大鼠.
产品编号 ABIN318755
发货至: 中国

Quick Overview for IRF7 抗体 (C-Term) (ABIN318755)

抗原

See all IRF7 抗体
IRF7 (Interferon Regulatory Factor 7 (IRF7))

适用

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人, 小鼠, 大鼠

宿主

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克隆类型

  • 59
  • 15
多克隆

标记

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This IRF7 antibody is un-conjugated

应用范围

  • 52
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  • 17
  • 14
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Western Blotting (WB)
  • 抗原表位

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    C-Term

    特异性

    This antibody detects an epitope within the C-terminal of Human Interferon Regulatory Factor 7 (IRF7).

    纯化方法

    Affinity Chromatography.

    免疫原

    14 amino acid peptide sequence near the carboxy terminus of Human IRF7.

    亚型

    IgG
  • 应用备注

    Western Blot: 1.0-2.0 μg/mL. This antibody detects a band of approximately 51 kDa in 293 whole cell lysate.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.

    限制

    仅限研究用
  • 浓度

    1.0 mg/mL

    缓冲液

    PBS containing 0.02 % Sodium Azide as preservative.

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freezing and thawing.

    储存条件

    4 °C/-20 °C

    储存方法

    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • 抗原

    IRF7 (Interferon Regulatory Factor 7 (IRF7))

    别名

    IRF7

    背景

    IRF7 is a 54kD transcriptional activator of type I interferons (IFNalpha/beta) in response to local and systemic viral infection. IRF7 is mostly expressed by plasmacytoid dendritic cells (pDC), which differentiate in response to IFNs and virus infection. This then stabilizes the IRF7 protein, in turn leading to increased IFN production. Multiple IRF7 transcript variants have been identified, although their individual functions have not yet been established.Synonyms: IRF-7, Interferon regulatory factor 7

    基因ID

    3665

    NCBI登录号

    NP_001563

    UniProt

    Q92985

    途径

    TLR signaling, Activation of Innate immune Response, Hepatitis C, Toll-Like Receptors Cascades, Autophagy
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