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IRF7 抗体 (C-Term)

IRF7 适用: 人, 小鼠, 大鼠 WB, IHC (p), EIA 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN500058
发货至: 中国
  • 抗原 See all IRF7 抗体
    IRF7 (Interferon Regulatory Factor 7 (IRF7))
    抗原表位
    • 17
    • 17
    • 15
    • 8
    • 5
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term
    适用
    • 69
    • 54
    • 53
    • 17
    • 8
    • 3
    • 2
    • 2
    • 1
    人, 小鼠, 大鼠
    宿主
    • 68
    • 2
    克隆类型
    • 57
    • 13
    多克隆
    标记
    • 23
    • 5
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    This IRF7 antibody is un-conjugated
    应用范围
    • 49
    • 18
    • 15
    • 14
    • 13
    • 13
    • 5
    • 4
    • 4
    • 3
    • 2
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
    特异性
    This antibody reacts to IRF7.
    纯化方法
    Affinity chromatography purified via peptide column
    免疫原
    IRF7 antibody was raised against a peptide corresponding to 14 amino acids near the carboxy-terminus of human IRF7.
    亚型
    IgG
    Top Product
    Discover our top product IRF7 Primary Antibody
  • 应用备注
    ELISA. Western Blot: 1 - 2 μg/mL. Immunohistochemistry.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    限制
    仅限研究用
  • 缓冲液
    PBS containing 0.02 % sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C
    储存方法
    Store the antibody undiluted at 2-8 °C.
  • Desnues, Macedo, Ordoñez-Rueda, Roussel-Queval, Malissen, Bruhns, Malissen, Alexopoulou: "The transcriptional repressor Gfi1 prevents lupus autoimmunity by restraining TLR7 signaling." in: European journal of immunology, Vol. 46, Issue 12, pp. 2801-2811, (2017) (PubMed).

  • 抗原
    IRF7 (Interferon Regulatory Factor 7 (IRF7))
    别名
    IRF7 (IRF7 产品)
    别名
    wu:fl24c03 antibody, zgc:66043 antibody, zgc:77947 antibody, IRF7 antibody, irf7 antibody, IRF-7H antibody, IRF7A antibody, IRF7B antibody, IRF7C antibody, IRF7H antibody, interferon regulatory factor 7 antibody, irf7 antibody, IRF7 antibody, Irf7 antibody
    背景
    Interferons (IFNs) are involved in a multitude of immune interactions during viral infections and play a major role in both the induction and regulation of innate and adaptive antiviral mechanisms. During infection, host-virus interactions signal downstream molecules such as transcription factors such as IFN regulatory factor-3 (IRF3) which can act to stimulate transcription of IFN-a/b genes. IRF7 has been shown to play a role in the transcriptional activation of virus-inducible cellular genes, including interferon beta chain genes. IRF7 play a major role in the innate immune pathway, interacting with the Toll-like receptor (TLR) adaptor proteins MyD88 and Tirp/TRAM and functioning as an intermediate TLR4 and TLR9 signaling. There are at least four differentially spliced isoforms of IRF7, although their function has not been clearly established.Synonyms: IRF-7, Interferon regulatory factor 7
    基因ID
    3665
    UniProt
    Q92985
    途径
    TLR signaling, Activation of Innate immune Response, Hepatitis C, Toll-Like Receptors Cascades, Autophagy
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