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CD45 抗体 (AA 1029-1249)

Name: CD45 抗体 (AA 1029-1249)
SKU: ABIN317498
Availability: OutOfStock

PTPRC 适用: 人 WB, IHC (p), EIA 宿主: 小鼠 Monoclonal 3G4 unconjugated

Immunohistochemistry (IHC) image for anti-Protein tyrosine Phosphatase, Receptor Type, C (PTPRC) (AA 1029-1249) antibody (ABIN317498) (CD45 抗体 (AA 1029-1249))

IHC

Western Blotting (WB) image for anti-Protein tyrosine Phosphatase, Receptor Type, C (PTPRC) (AA 1029-1249) antibody (ABIN317498) (CD45 抗体 (AA 1029-1249))

3 images

产品编号 ABIN317498

发货至: 中国

Datasheet as PDF

抗原 See all CD45 (PTPRC) 抗体

CD45 (PTPRC) (Protein tyrosine Phosphatase, Receptor Type, C (PTPRC))
抗原表位
16

16

14

13

12

10

9

7

6

6

3

3

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1
AA 1029-1249
适用
348

208

79

29

20

16

15

10

7

6

6

4

4

3

3

3

2

1

1

1

1

1

1
人
宿主
247

160

137

2

1
小鼠
Compatible Secondaries
克隆类型
411

128

1
单克隆
标记
164

52

44

43

34

13

12

11

10

9

8

8

8

6

6

6

6

6

6

5

4

4

4

4

4

4

4

4

4

4

4

4

3

3

3

3

2

2

2

2

2

2

2

1

1

1

1

1

1

1

1
This CD45 antibody is un-conjugated
应用范围
444

186

147

120

91

58

43

39

38

27

15

14

13

12

9

5

4

3

3

2

2

1

1

1

1

1

1
Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

特异性

The antibody recognizes Human CD45. Other species not tested.

产品特性

Synonyms: Leukocyte common antigen, L-CA, PTPRC, T200, CD45RB, CD45RO, CD45RA, CD45R

纯化方法

Protein-G affinity chromatography

免疫原

Recombinant human CD45 (1029-1249 aa) purified from E. coli.

克隆位点

3G4

亚型

IgG2a

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anti-Protein tyrosine Phosphatase, Receptor Type, C (PTPRC) (AA 24-575) antibody
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anti-Protein tyrosine Phosphatase, Receptor Type, C (PTPRC) (C-Term) antibody
PTPRC 适用: 人, 小鼠, 大鼠, 犬, 小鸡, Cow, Cat, 兔, 绵羊, Pig, 豚鼠, 山羊, 马, 猴, Hamster, 驴, Avian WB 宿主: 山羊 Polyclonal unconjugated

anti-Protein tyrosine Phosphatase, Receptor Type, C (PTPRC) antibody
PTPRC 适用: 人 FACS, IHC, WB, IF, StM 宿主: 兔 Monoclonal PTPRC-2877R unconjugated Recombinant Antibody

anti-Protein tyrosine Phosphatase, Receptor Type, C (PTPRC) antibody
PTPRC 适用: 人 FACS, WB, IP, IHC (p), ICC 宿主: 小鼠 Monoclonal MEM-28 unconjugated

anti-Protein tyrosine Phosphatase, Receptor Type, C (PTPRC) (AA 378-577) antibody
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anti-Protein tyrosine Phosphatase, Receptor Type, C (PTPRC) (AA 431-577) antibody
PTPRC 适用: 人 FACS, IHC, WB, ELISA, ICC, Neut 宿主: 小鼠 Monoclonal 7C9F12 unconjugated

应用备注

ELISA. Western blot (1/1,000-1/3,000), recommended starting dilution is 1/2000. Immunohistochemistry on Paraffin Sections (10 μg/mL).
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

限制

仅限研究用
状态

Liquid

浓度

1.0 mg/mL

缓冲液

PBS, pH 7.4, containing 0.09 % Sodium Azide as preservative.

储存液

Sodium azide

注意事项

This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

储存条件

4 °C/-20 °C

储存方法

Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer. Avoid repeated freezing and thawing.
Shelf life: one year from despatch.

有效期

12 months
抗原

CD45 (PTPRC) (Protein tyrosine Phosphatase, Receptor Type, C (PTPRC))

别名

CD45 / LCA (PTPRC 产品)

别名

PTPRC antibody, si:dkeyp-47c5.1 antibody, B220 antibody, CD45 antibody, CD45R antibody, GP180 antibody, L-CA antibody, LCA antibody, LY5 antibody, T200 antibody, Cd45 antibody, Ly-5 antibody, Lyt-4 antibody, loc antibody, Lca antibody, RT7 antibody, cd45 antibody, protein tyrosine phosphatase, receptor type C antibody, protein tyrosine phosphatase, receptor type, C antibody, receptor-type tyrosine-protein phosphatase C antibody, PTPRC antibody, ptprc antibody, LOC100074271 antibody, Ptprc antibody

背景

CD45 belongs to a family of heavily glycosylated, high molecular weight transmembrane glycoproteins expressed on all cells of haematopoietic origin. Structurally heterogeneous, CD45 consists of a family of eight isoforms ranging from 180,000 to 220,000 MW generated by alternative splicing of three exons differentially expressed on subpopulation of lymphocytes. CD45 protein tyrosine phosphatase activity plays a central role in T-cell activation. CD45 plays an important role in signal transduction inhibition or upregulation of various immunological functions.Synonyms: L-CA, Leukocyte common antigen, PTPRC, Receptor-type tyrosine-protein phosphatase C, T200

基因ID

5788

UniProt

P08575

途径

TCR Signaling, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, CXCR4-mediated Signaling Events, BCR Signaling