IL-6 抗体
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北京 101111
Quick Overview for IL-6 抗体 (ABIN317142)
抗原
See all IL-6 (IL6) 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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产品特性
- Synonyms: IL-6, Interferon beta-2, IFNB2, B-cell stimulatory factor 2, BSF-2, CDF, Hybridoma growthfactor, CTL differentiation factor
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纯化方法
- Purified IgG prepared by affinity chromatography on protein G
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免疫原
- Natural partially purified mouse IL-6.
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亚型
- IgG1
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应用备注
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ELISA. Functional Assays: 3 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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浓度
- 1.0mg/mL
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缓冲液
- Phosphate buffered saline
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储存液
- Azide free
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储存条件
- -20 °C
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储存方法
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Store the antibody at -20 °C. Avoid repeated freezing and thawing.
Shelf life: one year from despatch. -
有效期
- 12 months
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- IL-6 (IL6) (Interleukin 6 (IL6))
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别名
- Interleukin-6 (IL6)
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背景
- IL-6 is a multifunctional pro-inflammatory cytokine secreted by activated T cells, macrophages, endothelial cells, fibroblasts and osteoblasts, which acts as the principle inducer of the acute phase response in the liver. IL-6 signals through a membrane bound receptor complex consisting of the ligand-binding IL-6Ra chain (CD126) and the signal-transducing component gp130 (CD130), but can also stimulate cells expressing gp130 through a soluble IL-6R. IL-6 has been shown to stimulate B cell differentiation and subsequent immunoglobulin production, promote hybridoma growth, as well as regulating bone metabolism and stimulating energy mobilisation in muscle and fatty tissue.Synonyms: B-cell stimulatory factor 2, BSF-2, CDF, CTL differentiation factor, Hybridoma growth factor, IFNB2, IL-6, Interferon beta-2
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UniProt
- P08505
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途径
- TLR signaling, Hormone Transport, Negative Regulation of Hormone Secretion, Myometrial Relaxation and Contraction, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Regulation of Carbohydrate Metabolic Process, Autophagy, Cell RedoxHomeostasis, Cancer Immune Checkpoints, Inflammasome
抗原
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