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IL-6 抗体 (AA 25-211)

IL6 适用: 小鼠 WB, ELISA 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN3043248
发货至: 中国
  • 抗原 See all IL-6 (IL6) 抗体
    IL-6 (IL6) (Interleukin 6 (IL6))
    抗原表位
    • 18
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    AA 25-211
    适用
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    小鼠
    宿主
    • 194
    • 82
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    克隆类型
    • 212
    • 135
    • 1
    多克隆
    标记
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    This IL-6 antibody is un-conjugated
    应用范围
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    Western Blotting (WB), ELISA
    原理
    Rabbit IgG polyclonal antibody for Interleukin-6(IL6) detection. Tested with WB, ELISA in Mouse.
    交叉反应 (详细)
    No cross reactivity with other proteins.
    产品特性
    Rabbit IgG polyclonal antibody for Interleukin-6(IL6) detection. Tested with WB, ELISA in Mouse.
    Gene Name: interleukin 6
    Protein Name: Interleukin-6
    纯化方法
    Immunogen affinity purified.
    免疫原
    E.coli-derived mouse IL-6 recombinant protein (Position: F25-T211). Mouse IL-6 shares 40% and 85% amino acid (aa) sequences identity with human and rat IL-6, respectively.
    亚型
    IgG
    Top Product
    Discover our top product IL6 Primary Antibody
  • 应用备注
    WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Mouse, The detection limit for IL-6 is approximately 0.25 ng/lane under reducing conditions.
    ELISA: Concentration: 0.1-0.5 μg/mL, Tested Species: Mouse

    Notes: Tested Species: Species with positive results.
    Other applications have not been tested. Optimal dilutions should be determined by end users.
    说明

    Antibody can be supported by chemiluminescence kit ABIN921124 in WB.

    限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
    浓度
    500 μg/mL
    缓冲液
    Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    4 °C/-20 °C
    储存方法
    At -20°C for one year. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.
  • Wu, Li, Cui, Wu, Hong, Li, Wu, Jie, Wang, Li: "The Natural Flavone Acacetin Confers Cardiomyocyte Protection Against Hypoxia/Reoxygenation Injury via AMPK-Mediated Activation of Nrf2 Signaling Pathway." in: Frontiers in pharmacology, Vol. 9, pp. 497, (2018) (PubMed).

    Lu, Kang, Hu, Tang, Zhou, Yu, Li, Xu: "Angiotensin-(1-7) inhibits inflammation and oxidative stress to relieve lung injury induced by chronic intermittent hypoxia in rats." in: Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas, Vol. 49, Issue 10, pp. e5431, (2017) (PubMed).

    Chen, Zhao, Zhang, Yang, Zhao, Zhang, Yan, Pan, Li, Zhang, Li: "Tangshen Formula Attenuates Colonic Structure Remodeling in Type 2 Diabetic Rats." in: Evidence-based complementary and alternative medicine : eCAM, Vol. 2017, pp. 4064156, (2017) (PubMed).

    Li, Lu, Sun, Zuo, Wang, Yan: "Inhibition of endoplasmic reticulum stress signaling pathway: A new mechanism of statins to suppress the development of abdominal aortic aneurysm." in: PLoS ONE, Vol. 12, Issue 4, pp. e0174821, (2017) (PubMed).

    Chen, Wang, Li, Jiang, Lu, Zhou: "Heme Oxygenase-1 Promotes Delayed Wound Healing in Diabetic Rats." in: Journal of diabetes research, Vol. 2016, pp. 9726503, (2016) (PubMed).

    Wang, Qiu, Ren: "Inhibition of acute lung injury by rubriflordilactone in LPS-induced rat model through suppression of inflammatory factor expression." in: International journal of clinical and experimental pathology, Vol. 8, Issue 12, pp. 15954-9, (2016) (PubMed).

    Qin, Ma, Yang, Hu, Zhou, Fu, Tian, Liu, Xu, Shen: "A Triterpenoid Inhibited Hormone-Induced Adipocyte Differentiation and Alleviated Dexamethasone-Induced Insulin Resistance in 3T3-L1 adipocytes." in: Natural products and bioprospecting, Vol. 5, Issue 3, pp. 159-66, (2015) (PubMed).

    Chen, Zhao, Wu, Zou, Luo, Li, Xie, Liang: "The role of RIP1 and RIP3 in the development of aplastic anemia induced by cyclophosphamide and busulphan in mice." in: International journal of clinical and experimental pathology, Vol. 7, Issue 12, pp. 8411-20, (2015) (PubMed).

    Hu, Jing, Wang, Zhang, Yong, Wang: "The positive effects of Ginsenoside Rg1 upon the hematopoietic microenvironment in a D-Galactose-induced aged rat model." in: BMC complementary and alternative medicine, Vol. 15, pp. 119, (2015) (PubMed).

    Li, Zhang, Fu, Sun, Gong, Jiang, Zhang: "Dual pancreas- and lung-targeting therapy for local and systemic complications of acute pancreatitis mediated by a phenolic propanediamine moiety." in: Journal of controlled release : official journal of the Controlled Release Society, Vol. 212, pp. 19-29, (2015) (PubMed).

    Cui, Feng, Zhang, Jia: "The anti-inflammation effect of baicalin on experimental colitis through inhibiting TLR4/NF-?B pathway activation." in: International immunopharmacology, Vol. 23, Issue 1, pp. 294-303, (2015) (PubMed).

    Li, Chen, Zhang, Song, Mu: "Gastrodin inhibits neuroinflammation in rotenone-induced Parkinson's disease model rats." in: Neural regeneration research, Vol. 7, Issue 5, pp. 325-31, (2015) (PubMed).

    Gong, Wang, Yuan, Li, Gu, Zhao, Zhang, Jia, Feng, Liu: "Inhibition of Tumor Growth and Immunomodulatory Effects of Flavonoids and Scutebarbatines of Scutellaria barbata D. Don in Lewis-Bearing C57BL/6 Mice." in: Evidence-based complementary and alternative medicine : eCAM, Vol. 2015, pp. 630760, (2015) (PubMed).

    Li, Zhang, Jiang, Yin, Fan, Sun, Chen, Li, Liu: "Protective effects of thalidomide on pulmonary injuries in a rat model of paraquat intoxication." in: Journal of inflammation (London, England), Vol. 12, pp. 46, (2015) (PubMed).

    Li, Qian, Ju, Wang: "Upregulation of Toll-like receptor 2 expression in colorectal cancer infected by human cytomegalovirus." in: Oncology letters, Vol. 9, Issue 1, pp. 365-370, (2014) (PubMed).

    Liu, Zeng, Liu, Wang, Maitz, Wang, Liu, Chen, Huang: "Surface modification with dopamine and heparin/poly-L-lysine nanoparticles provides a favorable release behavior for the healing of vascular stent lesions." in: ACS applied materials & interfaces, Vol. 6, Issue 11, pp. 8729-43, (2014) (PubMed).

    Zhu, Mu, Zeng, Xu, Liu, Zhang, Li, Chen, Li, Wang: "Ginsenoside Rg1 prevents cognitive impairment and hippocampus senescence in a rat model of D-galactose-induced aging." in: PLoS ONE, Vol. 9, Issue 6, pp. e101291, (2014) (PubMed).

    Huang, Du, Fan, Lv, Qian, Zhang, Han, Chen, Wu, Jin: "The effect of proinflammatory cytokines on IL-17RA expression in NSCLC." in: Medical oncology (Northwood, London, England), Vol. 31, Issue 9, pp. 144, (2014) (PubMed).

    Ye, Zheng, Fan, Qin, Li, Tang, Ai, Zhang, Bian, Dang, Huang, Zhou, Zhou, Xiong, Yan, Ma, Li: "Lactoferrin deficiency promotes colitis-associated colorectal dysplasia in mice." in: PLoS ONE, Vol. 9, Issue 7, pp. e103298, (2014) (PubMed).

    Wang, Zhou, Chen, Zhu: "Putative role of ischemic postconditioning in a rat model of limb ischemia and reperfusion: involvement of hypoxia-inducible factor-1? expression." in: Brazilian journal of medical and biological research = Revista brasileira de pesquisas me?dicas e biolo?gicas / Sociedade Brasileira de Biofi?sica ... [et al.], Vol. 47, Issue 9, pp. 738-45, (2014) (PubMed).

  • 抗原
    IL-6 (IL6) (Interleukin 6 (IL6))
    别名
    IL6 (IL6 产品)
    别名
    BSF2 antibody, HGF antibody, HSF antibody, IFNB2 antibody, IL-6 antibody, Il-6 antibody, ILg6 antibody, Ifnb2 antibody, il6 antibody, CHIL-6 antibody, interleukin 6 antibody, interleukin-6 antibody, IL6 antibody, Il6 antibody, il-6 antibody, IL-6 antibody
    背景
    Interleukin-6 (IL-6) is a protein that in humans is encoded by the IL6 gene. IL-6 is an interleukin that acts as both a pro-inflammatory and anti-inflammatory cytokine. It is secreted by T cells and macrophages to stimulate immune response to trauma, especially burns or other tissue damage leading to inflammation. IL-6 is one of the most important mediators of fever and of the acute phase response. IL-6 is also essential for hybridoma growth and is found in many supplemental cloning media such as briclone. Bowcock et al. (1988) assigned the IL6 gene to chromosome 7p21. By in situ hybridization and Southern blot analysis of mouse-human hybrid cell lines, Sutherland et al. (1988) mapped the IL-6 gene to chromosome 7p15.

    Synonyms: Interleukin BSF 2 antibody|B cell differentiation factor antibody|B cell stimulatory factor 2 antibody|B-cell stimulatory factor 2 antibody|BSF 2 antibody|BSF-2 antibody|BSF2 antibody|CDF antibody|CTL differentiation factor antibody|Cytotoxic T cell differentiation factor antibody|Hepatocyte stimulating factor antibody|HGF antibody|HPGF antibody|HSF antibody|Hybridoma growth factor antibody|Hybridoma growth factor Interferon beta-2 antibody|Hybridoma plasmacytoma growth factor antibody|IFN-beta-2 antibody|IFNB2 antibody|IL 6 antibody|IL-6 antibody|IL6 antibody|IL6 protein antibody|IL6_HUMAN antibody|Interferon beta 2 antibody|Interferon beta-2 antibody|Interleukin 6 (interferon beta 2) antibody|Interleukin 6 antibody|Interleukin BSF 2 antibody|Interleukin-6 antibody|Interleukin6 antibody
    基因ID
    16193
    UniProt
    P08505
    途径
    TLR signaling, Hormone Transport, Negative Regulation of Hormone Secretion, Myometrial Relaxation and Contraction, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Regulation of Carbohydrate Metabolic Process, Autophagy, Cell RedoxHomeostasis, Cancer Immune Checkpoints, Inflammasome
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