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IL-6 抗体 (AA 111-150)

Name: IL-6 抗体 (AA 111-150)
SKU: ABIN728083
Availability: OutOfStock

IL6 适用: 人, 小鼠, 大鼠, 兔, Cow WB, ELISA, FACS, IF (p), IHC (p), IF (cc), IHC (fro) 宿主: 兔 Polyclonal unconjugated

Protein expression of PPARγ, IL-6, and TNF-α in WAT after vibration for 8 weeks.

Antigen: 2 µg/100 µL Primary: Antiserum, 1:500, 1:1000, 1:2000, 1:4000, 1:8000, 1:16000, 1:32000; Secondary: HRP conjugated Rabbit Anti-Goat IgG at 1: 5000; TMB staining Read the data in Microplate Reader by 450nm.

ELISA

Formalin-fixed and paraffin embedded mouse lung tissue labeled with Anti-IL-6(mo, rat) Polyclonal Antibody, Unconjugated (ABIN728083) at 1:200, followed by conjugation to the secondary antibody and DAB staining

IHC

L1 mouse lung lysates L2 protein provided by the end user lysates probed with Anti IL-6 Polyclonal Antibody, Unconjugated (ABIN728083) at 1:200 overnight at 4 °C.

SDS

Formalin-fixed and paraffin embedded rat liver tissue labeled with Anti-IL-6(mo, rat) Polyclonal Antibody, Unconjugated (ABIN728083) at 1:200, followed by conjugation to the secondary antibody and DAB staining

IHC

Formalin-fixed and paraffin embedded mouse lung tissue labeled with Anti-IL-6(mo, rat) Polyclonal Antibody, Unconjugated at 1:200, followed by conjugation to the secondary antibody and DAB staining

IHC (p)

6 images

(14 references)

产品编号 ABIN728083

发货至: 中国

Datasheet as PDF

抗原 See all IL-6 (IL6) 抗体

IL-6 (IL6) (Interleukin 6 (IL6))
抗原表位
19

17

15

15

15

15

8

8

7

7

7

5

5

5

5

4

4

3

3

1

1

1

1

1

1

1

1
AA 111-150
适用
169

128

68

28

21

20

15

13

7

6

4

3

3

3

2
人, 小鼠, 大鼠, 兔, Cow
宿主
194

82

54

11

4

3

2
兔
Compatible Secondaries
克隆类型
212

135

1
多克隆
标记
189

57

26

10

9

8

4

4

4

4

4

4

3

3

3

3

3

2

2

2

1

1

1

1

1

1

1
This IL-6 antibody is un-conjugated
应用范围
261

131

104

52

49

46

40

40

38

30

25

25

21

20

14

8

7

6

6

5

3

2

2

1

1

1

1

1

1

1

1

1

1

1
Western Blotting (WB), ELISA, Flow Cytometry (FACS), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunohistochemistry (Frozen Sections) (IHC (fro))

交叉反应

Cow, 人, 小鼠, 兔, 大鼠

纯化方法

Purified by Protein A.

免疫原

KLH conjugated synthetic peptide derived from mouse IL-6

亚型

IgG
anti-Interleukin 6 (IL6) antibody
IL6 适用: 人 ELISA, FACS, Func, ELISpot 宿主: 小鼠 Monoclonal B-E8 unconjugated

anti-Interleukin 6 (IL6) (AA 21-211) antibody
IL6 适用: 大鼠 WB, IHC, IP, ICC 宿主: 小鼠 Monoclonal C4 unconjugated

anti-Interleukin 6 (IL6) (AA 27-212) antibody
IL6 适用: 猕猴 WB, IHC, IP, ICC 宿主: 小鼠 Monoclonal 18# unconjugated

anti-Interleukin 6 (IL6) (AA 21-211) antibody
IL6 适用: 大鼠 WB, IHC, IP, IF/ICC 宿主: 小鼠 Monoclonal unconjugated

anti-Interleukin 6 (IL6) (AA 101-150) antibody
IL6 适用: 小鼠, 大鼠 WB, ELISA, IF (p), IHC (p), IF (cc), IHC (fro) 宿主: 兔 Polyclonal unconjugated

anti-Interleukin 6 (IL6) (AA 27-241) antibody
IL6 适用: 兔 WB, IHC, IP, ICC 宿主: 小鼠 Monoclonal C305 unconjugated

anti-Interleukin 6 (IL6) (AA 25-211) antibody
IL6 适用: 大鼠 WB 宿主: 兔 Polyclonal unconjugated

anti-Interleukin 6 (IL6) (AA 27-55) antibody
IL6 适用: 人 WB, ELISA, IHC, FACS 宿主: 兔 Polyclonal unconjugated

anti-Interleukin 6 (IL6) (AA 26-50) antibody
IL6 适用: 人, 大鼠 ELISA, IF (p), IHC (p), IF (cc), IHC (fro) 宿主: 兔 Polyclonal unconjugated

anti-Interleukin 6 (IL6) (AA 110-185) antibody
IL6 适用: 人, 小鼠, 大鼠 WB, ELISA, IF (p), IHC (p), IF (cc), IHC (fro) 宿主: 兔 Polyclonal unconjugated

应用备注

WB 1:300-5000
ELISA 1:500-1000
FCM 1:20-100
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

限制

仅限研究用
状态

Liquid

浓度

1 μg/μL

缓冲液

0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

储存液

ProClin

注意事项

This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

储存条件

4 °C,-20 °C

储存方法

Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

有效期

12 months
Brockmann, Corkhill, Jaroslawska, Dege, Brockmann, Kociok, Joussen: "Systemic Rho-kinase inhibition using fasudil in mice with oxygen-induced retinopathy." in: Graefe's archive for clinical and experimental ophthalmology, Vol. 257, Issue 8, pp. 1699-1708, (2019) (PubMed).

Bai, Lv, Wang, Sun, Zhang: "LncRNA NEAT1 promotes inflammatory response and induces corneal neovascularization" in: Journal of molecular endocrinology, Vol. 61, Issue 4, pp. 231-239, (2019) (PubMed).

Sun, Li, Jia, Wang, Li, Hu, Tian, Yang, Xing, Zhang, Wang, Xu, Wang, Zhang, Ren: "Neuroprotection by IFN-γ via astrocyte-secreted IL-6 in acute neuroinflammation." in: Oncotarget, Vol. 8, Issue 25, pp. 40065-40078, (2018) (PubMed).

Haffner-Luntzer, Fischer, Prystaz, Liedert, Ignatius: "The inflammatory phase of fracture healing is influenced by oestrogen status in mice." in: European journal of medical research, Vol. 22, Issue 1, pp. 23, (2017) (PubMed).

Prystaz, Kaiser, Kovtun, Haffner-Luntzer, Fischer, Rapp, Liedert, Strauss, Waetzig, Rose-John, Ignatius: "Distinct Effects of IL-6 Classic and Trans-Signaling in Bone Fracture Healing." in: The American journal of pathology, Vol. 188, Issue 2, pp. 474-490, (2017) (PubMed).

Taskin, Gungor, Adali, Yay, Onder, Inceboz: "A Humanized Anti-Interleukin 6 Receptor Monoclonal Antibody, Tocilizumab, for the Treatment of Endometriosis in a Rat Model." in: Reproductive sciences (Thousand Oaks, Calif.), Vol. 23, Issue 5, pp. 662-9, (2016) (PubMed).

Kuracha, Thomas, Loggie, Govindarajan: "Patient-derived xenograft mouse models of pseudomyxoma peritonei recapitulate the human inflammatory tumor microenvironment." in: Cancer medicine, Vol. 5, Issue 4, pp. 711-9, (2016) (PubMed).

Zhu, Wang, Yang, Wang, Li, Zhou, Zhang: "Hematopoietic Effects of Paeoniflorin and Albiflorin on Radiotherapy-Induced Myelosuppression Mice." in: Evidence-based complementary and alternative medicine : eCAM, Vol. 2016, pp. 5789381, (2016) (PubMed).

Sun, Zeng, Cao, Song, Zhang, Liu: "Vibration Training Triggers Brown Adipocyte Relative Protein Expression in Rat White Adipose Tissue." in: BioMed research international, Vol. 2015, pp. 919401, (2015) (PubMed).

Taskin, Topcu, Yay, Erken, Balcio?lu, Adali, Hismiogullar?: "Prevention of ovarian hyperstimulation syndrome in a rat model: comparison of the efficacy of tocilizumab with that of ranibizumab, cabergoline, and a gonadotropin-releasing hormone antagonist." in: Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology, pp. 1-6, (2015) (PubMed).

Luo, Wang, Li, Wei, Zhang, Liu, Wang, Niu, Wang: "Maternal bisphenol a diet induces anxiety-like behavior in female juvenile with neuroimmune activation." in: Toxicological sciences : an official journal of the Society of Toxicology, Vol. 140, Issue 2, pp. 364-73, (2015) (PubMed).

Takayanagi, Crawford, Kobayashi, Obama, Tsuji, Elliott, Hashimoto, Rizzo, Eguchi: "Caveolin 1 is critical for abdominal aortic aneurysm formation induced by angiotensin II and inhibition of lysyl oxidase." in: Clinical science (London, England : 1979), Vol. 126, Issue 11, pp. 785-94, (2014) (PubMed).
抗原

IL-6 (IL6) (Interleukin 6 (IL6))

别名

IL-6 (IL6 产品)

别名

BSF2 antibody, HGF antibody, HSF antibody, IFNB2 antibody, IL-6 antibody, Il-6 antibody, ILg6 antibody, Ifnb2 antibody, il6 antibody, CHIL-6 antibody, interleukin 6 antibody, interleukin-6 antibody, IL6 antibody, Il6 antibody, il-6 antibody, IL-6 antibody

背景

Synonyms: Il-6, Interleukin-6, B-cell hybridoma growth factor, Interleukin HP-1, Il6
Background: Cytokine with a wide variety of biological functions. It is a potent inducer of the acute phase response. Plays an essential role in the final differentiation of B-cells into Ig-secreting cells Involved in lymphocyte and monocyte differentiation. Acts on B-cells, T-cells, hepatocytes, hematopoietic progenitor cells and cells of the CNS. Required for the generation of T(H)17 cells. Also acts as a myokine. It is discharged into the bloodstream after muscle contraction and acts to increase the breakdown of fats and to improve insulin resistance. It induces myeloma and plasmacytoma growth and induces nerve cells differentiation.

基因ID

16193

UniProt

P08505

途径

TLR signaling, Hormone Transport, Negative Regulation of Hormone Secretion, Myometrial Relaxation and Contraction, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Regulation of Carbohydrate Metabolic Process, Autophagy, Cell RedoxHomeostasis, Cancer Immune Checkpoints, Inflammasome