Notch1 抗体 (PE)
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- 抗原 See all Notch1 (NOTCH1) 抗体
- Notch1 (NOTCH1) (Notch 1 (NOTCH1))
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适用
- 人, 小鼠
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This Notch1 antibody is conjugated to PE
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应用范围
- Western Blotting (WB), Immunohistochemistry (IHC), Flow Cytometry (FACS), Immunohistochemistry (Frozen Sections) (IHC (fro))
- 特异性
- Specific for mouse Notch1, a single transmembrane receptor which is expressed in a range of cells including hematopoietic cells in mouse fetal liver, adult thymus and bone marrow. Notch1 plays a role in embryonic development and tissue homeostasis in the adult. Recent work has suggested a further role for this receptor in the regulation of lymphopoiesis and myelopoiesis. Following ligand binding, Notch1 is cleaved in the transmembrane domain, releasing the Notch intracellular domain (NICD) to translocate to the nucleus, where it plays a role in the modulation of gene expression.
- 纯化方法
- Protein G purified
- 免疫原
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Synthetic peptide corresponding to cdc10-NCR region within mouse Notch1.
Type of Immunogen: Synthetic peptide - 亚型
- IgG1
- Top Product
- Discover our top product NOTCH1 Primary Antibody
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- 应用备注
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Approved: Flo (1:1 - 1:10), IHC, IHC-Fr, WB
Usage: The applications listed have been tested for the unconjugated form of this product. Other forms have not been tested. Flow Cytometry: Use 10 μL of the suggested working dilution to label 1x10^6 cells in 100 μL. Membrane permeabilization is required for this application. - 说明
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Target Species of Antibody: Mouse
- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Distilled Water.
- 浓度
- Lot specific
- 缓冲液
- Lyophilized, PBS, pH 7.4, 0.09 % sodium azide, 1 % BSA.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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- 抗原
- Notch1 (NOTCH1) (Notch 1 (NOTCH1))
- 别名
- NOTCH1 (NOTCH1 产品)
- 别名
- notch1 antibody, NOTCH1 antibody, hn1 antibody, tan1 antibody, notch antibody, xotch antibody, xnotch antibody, notch-1 antibody, xnotch1 antibody, TAN1 antibody, hN1 antibody, 9930111A19Rik antibody, Mis6 antibody, N1 antibody, Tan1 antibody, lin-12 antibody, NOTCH antibody, Xotch antibody, notch1-a antibody, notch 1 antibody, fibropellin-1 antibody, Notch homolog 1, translocation-associated (Drosophila) antibody, Notch homolog 1, translocation-associated antibody, notch 1 S homeolog antibody, notch1 antibody, LOC100631526 antibody, NOTCH1 antibody, Notch1 antibody, notch1.S antibody
- 背景
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Name/Gene ID: NOTCH1
Synonyms: NOTCH1, Notch 1, TAN1 - 基因ID
- 4851
- UniProt
- P46531
- 途径
- Notch Signaling, Stem Cell Maintenance, Regulation of Muscle Cell Differentiation, Tube Formation, Skeletal Muscle Fiber Development
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