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- 抗原 See all HDAC8 抗体
- HDAC8 (Histone Deacetylase 8 (HDAC8))
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抗原表位
- AA 18-33, N-Term
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适用
- 人, 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This HDAC8 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- 原理
- Rabbit IgG polyclonal antibody for Histone deacetylase 8(HDAC8) detection. Tested with WB, IHC-P in Human,Mouse,Rat.
- 序列
- YIYSPEYVSM CDSLAK
- 交叉反应 （详细）
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Predicted Cross Reactivity: mouse
No cross reactivity with other proteins.
Predicted Cross Reactivity: Species predicted to be fit for the product based on sequence similarities. - 产品特性
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Rabbit IgG polyclonal antibody for Histone deacetylase 8(HDAC8) detection. Tested with WB, IHC-P in Human,Mouse,Rat.
Gene Name: histone deacetylase 8
Protein Name: Histone deacetylase 8(HD8) - 纯化方法
- Immunogen affinity purified.
- 免疫原
- A synthetic peptide corresponding to a sequence at the N-terminus of human HDAC8(18-33aa YIYSPEYVSMCDSLAK), different from the related mouse and rat sequences by two amino acids.
- 亚型
- IgG
- Top Product
- Discover our top product HDAC8 Primary Antibody
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anti-Histone Deacetylase 8 (HDAC8) antibody
KO Validated HDAC8 适用: 人 WB, IHC, IF, IP 宿主: 兔 Monoclonal unconjugated
anti-Histone Deacetylase 8 (HDAC8) (AA 1-377) antibodyHDAC8 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 2F4 unconjugated
anti-Histone Deacetylase 8 (HDAC8) (AA 1-100) antibodyHDAC8 适用: 人 WB, ELISA, IP 宿主: 小鼠 Monoclonal 2F4 unconjugated
anti-Histone Deacetylase 8 (HDAC8) (pSer39) antibodyHDAC8 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Histone Deacetylase 8 (HDAC8) antibodyHDAC8 适用: 人, 小鼠, 大鼠 WB, IHC (p), IF (cc) 宿主: 兔 Monoclonal 4C3 unconjugated
anti-Histone Deacetylase 8 (HDAC8) (AA 1-377) antibodyHDAC8 适用: 人 IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Histone Deacetylase 8 (HDAC8) antibodyHDAC8 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Histone Deacetylase 8 (HDAC8) (N-Term) antibodyHDAC8 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Histone Deacetylase 8 (HDAC8) (C-Term) antibodyHDAC8 适用: 人, 小鼠, 大鼠, 猴, 兔, Cow, 马 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Histone Deacetylase 8 (HDAC8) (AA 151-250) antibodyHDAC8 适用: 人, 小鼠 ELISA, IHC (p), IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
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- 应用备注
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WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human, Rat, Predicted Species: Mouse
IHC-P: Concentration: 0.5-1 μg/mL, Tested Species: Human, Rat, Predicted Species: Mouse, Epitope Retrieval by Heat: Boiling the paraffin sections in 10 mM citrate buffer, pH 6.0, for 20 mins is required for the staining of formalin/paraffin sections.
Notes: Tested Species: Species with positive results. Predicted Species: Species predicted to be fit for the product based on sequence similarities. Other applications have not been tested. Optimal dilutions should be determined by end users. - 说明
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Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).
- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
- 浓度
- 500 μg/mL
- 缓冲液
- Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg Sodium azide.
- 储存液
- Thimerosal (Merthiolate), Sodium azide
- 注意事项
- This product contains Sodium azide and Thimerosal (Merthiolate): POISONOUS AND HAZARDOUS SUBSTANCES which should be handled by trained staff only.
- 注意事项
- Avoid repeated freezing and thawing.
- 储存条件
- 4 °C/-20 °C
- 储存方法
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At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing. - 有效期
- 12 months
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- 抗原
- HDAC8 (Histone Deacetylase 8 (HDAC8))
- 别名
- HDAC8 (HDAC8 产品)
- 别名
- HD8 antibody, CDLS5 antibody, HDACL1 antibody, MRXS6 antibody, RPD3 antibody, WTS antibody, 2610007D20Rik antibody, RGD1562895 antibody, wu:fd19a02 antibody, zgc:66196 antibody, ATHDA8 antibody, HDA8 antibody, HISTONE DEACETYLASE 8 antibody, T27G7.14 antibody, T27G7_14 antibody, histone deacetylase 8 antibody, histone deacetylase 8 antibody, histone deacetylase 8 L homeolog antibody, CC1G_05302 antibody, hdac8 antibody, HDAC8 antibody, Hdac8 antibody, hdac8.L antibody, HDA08 antibody
- 背景
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HDAC8, Histone deacetylase 8, is an enzyme that in humans is encoded by the HDAC8 gene, and is biologically involved in skull morphogenesis and metabolic control of the ERR-alpha/PGC1-alpha transcriptional complex. Sequence analysis predicted that the 377-amino acid HDAC8 protein contains the 9 conserved HDAC blocks that are presumably important for catalytic function. HDAC8 shares 54 % sequence similarity with HDAC1 and HDAC2 and 39 % similarity with HDAC3, making it a class I HDAC. Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene belongs to class I of the histone deacetylase/acuc/apha family. It has histone deacetylase activity and represses transcription when tethered to a promoter.
Synonyms: CDA07 antibody|HD 8 antibody|HD8 antibody|HDAC 8 antibody|Hdac8 antibody|HDAC8_HUMAN antibody|HDACL 1 antibody|HDACL1 antibody|Histone deacetylase 8 antibody|Histone deacetylase like 1 antibody|RPD 3 antibody|RPD3 antibody - 途径
- Cellular Glucan Metabolic Process
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