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HDAC8 抗体

(Histone Deacetylase 8 (HDAC8))
Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene belongs to class I of the histone deacetylase family. It catalyzes the deacetylation of lysine residues in the histone N-terminal tails and represses transcription in large multiprotein complexes with transcriptional co-repressors. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2009].
HDAC8 抗体 HDAC8 抗体 HDAC8 抗体 (ABIN7267714)

KO Validated HDAC8 适用: 人 WB, IHC, IF, IP 宿主: 兔 Monoclonal unconjugated

HDAC8 抗体  (AA 1-377) HDAC8 抗体  (AA 1-377) HDAC8 抗体 (AA 1-377) (ABIN527747)

HDAC8 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 2F4 unconjugated

HDAC8 抗体  (AA 1-100) HDAC8 抗体  (AA 1-100) HDAC8 抗体 (AA 1-100) (ABIN527748)

HDAC8 适用: 人 WB, ELISA, IP 宿主: 小鼠 Monoclonal 2F4 unconjugated

HDAC8 抗体 by Grade

Find HDAC8 抗体 with a specific Grade. The Grade listed below are among those available. Click on a link to go to the corresponding products.

HDAC8 抗体 by 适用

Find HDAC8 抗体 for a variety of species such as anti-Human HDAC8, anti-Mouse HDAC8, anti-Rat HDAC8. The species listed below are among those available. Click on a link to go to the corresponding products.

HDAC8 抗体 by 应用范围

Find HDAC8 抗体 validated for a specific application such as WB, ELISA, IHC, IF (cc). Some of the available applications are listed below. Click on a link to go to the corresponding products.

HDAC8 抗体 by 抗体来源

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HDAC8 抗体 by 抗原表位

Find HDAC8 抗体 with a specific epitope. The epitopes listed below are among those available. Click on a link to go to the corresponding products.

HDAC8 抗体 by 克隆形成能力

Find available monoclonal or polyclonal HDAC8 抗体. Click on a link to go to the corresponding products.

HDAC8 抗体 by 克隆

Find HDAC8 抗体 with a specific 克隆. The 克隆 listed below are among those available. Click on a link to go to the corresponding products.

HDAC8 抗体 by 标记

Find HDAC8 抗体 with a specific conjugate such as Biotin, FITC, HRP. The conjugates listed below are among those available. Click on a link to go to the corresponding products.

Popular HDAC8 抗体

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB, IHC, IF, IP
Validations
  • (7)
Cat. No. ABIN7267714
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, ELISA, IF
Validations
  • (5)
Cat. No. ABIN527747
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application WB, ELISA, IP
Validations
  • (4)
Cat. No. ABIN527748
Quantity 100 μg
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application WB, IHC, ELISA, IF, ICC
Validations
  • (4)
Cat. No. ABIN6255291
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application WB, IHC (p), IF (cc)
Validations
  • (3)
Cat. No. ABIN5557483
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application IHC, ELISA, IF
Validations
  • (3)
Cat. No. ABIN7155327
Quantity 100 μg
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application WB, IHC, ELISA
Validations
  • (3)
Cat. No. ABIN7239992
Quantity 200 μL
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application WB, IHC, ELISA, IF, ICC
Validations
  • (3)
Cat. No. ABIN6262191
Quantity 100 μL
Datasheet Datasheet
Reactivity Cow, Horse, Human, Monkey, Mouse, Rabbit, Rat
Application WB, IHC, IHC (p)
Validations
  • (3)
Cat. No. ABIN6736397
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Mouse
Application ELISA, IHC (p), IF (cc), IF (p), IHC (fro)
Validations
  • (2)
Cat. No. ABIN681268
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, IHC, ELISA
Validations
  • (2)
Cat. No. ABIN7181410
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application WB, IHC, ELISA
Validations
  • (2)
Cat. No. ABIN7155328
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application WB, IHC, ELISA
Validations
  • (2)
Cat. No. ABIN3182026
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application IHC, ELISA, IF
Validations
  • (2)
Cat. No. ABIN7138593
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, IP
Validations
  • (2)
Cat. No. ABIN527745
Quantity 100 μL
Datasheet Datasheet

Latest Publications for our HDAC8 抗体

Emmons, Faião-Flores, Sharma, Thapa, Messina, Becker, Schadendorf, Seto, Sondak, Koomen, Chen, Lau, Wan, Licht, Smalley: "HDAC8 Regulates a Stress Response Pathway in Melanoma to Mediate Escape from BRAF Inhibitor Therapy." in: Cancer research, Vol. 79, Issue 11, pp. 2947-2961, (2019) (PubMed).

Liu, Jiang, Loo, Hsu, Hsiang, Marcotrigiano, Gale: "Regulation of Retinoic Acid Inducible Gene-I (RIG-I) Activation by the Histone Deacetylase 6." in: EBioMedicine, Vol. 9, pp. 195-206, (2017) (PubMed).

Mao, Hou, Cao, Wang, Li, Chen, Fei, Hurren, Gronda, Wu, Trudel, Schimmer: "The tricyclic antidepressant amitriptyline inhibits D-cyclin transactivation and induces myeloma cell apoptosis by inhibiting histone deacetylases: in vitro and in silico evidence." in: Molecular pharmacology, Vol. 79, Issue 4, pp. 672-80, (2011) (PubMed).

Lee, Rezai-Zadeh, Seto: "Negative regulation of histone deacetylase 8 activity by cyclic AMP-dependent protein kinase A." in: Molecular and cellular biology, Vol. 24, Issue 2, pp. 765-73, (2003) (PubMed).

Hu, Chen, Fredrickson, Zhu, Kirkpatrick, Zhang, Johanson, Sung, Liu, Winkler: "Cloning and characterization of a novel human class I histone deacetylase that functions as a transcription repressor." in: The Journal of biological chemistry, Vol. 275, Issue 20, pp. 15254-64, (2000) (PubMed).

McDonell, Ramser, Francis, Vinet, Rider, Sudbrak, Riesselman, Yaspo, Reinhardt, Monaco, Ross, Kahn, Kearney, Buckle, Chelly: "Characterization of a highly complex region in Xq13 and mapping of three isodicentric breakpoints associated with preleukemia." in: Genomics, Vol. 64, Issue 3, pp. 221-9, (2000) (PubMed).

Van den Wyngaert, de Vries, Kremer, Neefs, Verhasselt, Luyten, Kass: "Cloning and characterization of human histone deacetylase 8." in: FEBS letters, Vol. 478, Issue 1-2, pp. 77-83, (2000) (PubMed).

Aliases for HDAC8 抗体

histone deacetylase 8 (CC1G_05302) 抗体
histone deacetylase 8 (hdac8) 抗体
histone deacetylase 8 (HDAC8) 抗体
histone deacetylase 8 (Hdac8) 抗体
histone deacetylase 8 L homeolog (hdac8.L) 抗体
histone deacetylase 8 (HDA08) 抗体
2610007D20Rik 抗体
ATHDA8 抗体
CDLS5 抗体
HD8 抗体
HDA8 抗体
HDACL1 抗体
HISTONE DEACETYLASE 8 抗体
histone deacetylase 8 抗体
MRXS6 抗体
RGD1562895 抗体
RPD3 抗体
T27G7.14 抗体
T27G7_14 抗体
WTS 抗体
wu:fd19a02 抗体
zgc:66196 抗体
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