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MAP2K3 抗体 (C-Term)

Name: MAP2K3 抗体 (C-Term)
SKU: ABIN3044392
Availability: OutOfStock

There is 1 publication for this product available. The 兔多克隆 anti-MAP2K3 antibody is suitable to detect MAP2K3 in samples from 人, 小鼠和大鼠. It has been validated for WB 和 IHC.

Western Blotting (WB) image for anti-Mitogen-Activated Protein Kinase Kinase 3 (MAP2K3) (C-Term) antibody (ABIN3044392) (MAP2K3 抗体 (C-Term))

Anti-MEK3 antibody, IHC(P) IHC(P): Human Mammary Cancer Tissue (MAP2K3 抗体 (C-Term))

IHC

Lane 9: COLO320 Cell Lysate (MAP2K3 抗体 (C-Term))

3 images

(1 reference)

产品编号 ABIN3044392

发货至: 中国

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Quick Overview for MAP2K3 抗体 (C-Term) (ABIN3044392)

抗原

See all MAP2K3 抗体

MAP2K3 (Mitogen-Activated Protein Kinase Kinase 3 (MAP2K3))

适用

人, 小鼠, 大鼠

宿主

兔

克隆类型

多克隆

标记

This MAP2K3 antibody is un-conjugated

应用范围

Western Blotting (WB), Immunohistochemistry (IHC)

Discover our top product MAP2K3 Primary Antibody

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C-Term

原理

Anti-MEK3/MAP2K3 Antibody

序列

MEHPFFTLHK TKKTD

特异性

No cross reactivity with other proteins.

交叉反应（详细）

No cross-reactivity with other proteins

预测反应

identical to the related mouse,rat sequences.

产品特性

Anti-MEK3/MAP2K3 Antibody. Tested in IHC, WB applications. This antibody reacts with Human, Mouse, Rat.

纯化方法

Immunogen affinity purified.

免疫原

A synthetic peptide corresponding to a sequence at the C-terminus of human MEK3, identical to the related mouse and rat sequences.

亚型

IgG
anti-Mitogen-Activated Protein Kinase Kinase 3 (MAP2K3) (AA 1-170) antibody
MAP2K3 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated

anti-Mitogen-Activated Protein Kinase Kinase 3 (MAP2K3) antibody
MAP2K3 适用: 人, 小鼠, 犬, 猴 WB, IHC, IF, IHC (p) 宿主: 小鼠 Monoclonal 5D3 unconjugated

anti-Mitogen-Activated Protein Kinase Kinase 3 (MAP2K3) antibody
MAP2K3 适用: 人, 犬, 猴 WB, IHC, IF, IHC (p) 宿主: 小鼠 Monoclonal 5C7 unconjugated

anti-Mitogen-Activated Protein Kinase Kinase 3 (MAP2K3) (AA 1-138) antibody
MAP2K3 适用: 人 IHC, ELISA, ICC, FACS 宿主: 小鼠 Monoclonal 2E12D11 unconjugated

anti-Mitogen-Activated Protein Kinase Kinase 3 (MAP2K3) antibody
KD Validated MAP2K3 适用: 人 WB, IF (p), FACS 宿主: 兔 Monoclonal 23GB2420 unconjugated Recombinant Antibody

anti-Mitogen-Activated Protein Kinase Kinase 3 (MAP2K3) (C-Term) antibody
MAP2K3 适用: 人, 小鼠, 大鼠 WB, IHC, IF, ICC, FACS 宿主: 兔 Polyclonal unconjugated

anti-Mitogen-Activated Protein Kinase Kinase 3 (MAP2K3) (AA 1-100) antibody
MAP2K3 适用: 人 WB, ELISA, IHC (p), IP 宿主: 小鼠 Monoclonal 1D10 unconjugated

anti-Mitogen-Activated Protein Kinase Kinase 3 (MAP2K3) antibody
MAP2K3 适用: 人, 小鼠, 大鼠, 犬, 猴 WB, IHC, IF, IHC (p) 宿主: 小鼠 Monoclonal 5F2 unconjugated

anti-Mitogen-Activated Protein Kinase Kinase 3 (MAP2K3) (AA 15-45), (N-Term) antibody
MAP2K3 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal RB0928 unconjugated

anti-Mitogen-Activated Protein Kinase Kinase 3 (MAP2K3) antibody
MAP2K3 适用: 人, 小鼠, 大鼠, 犬, 猴 WB, IHC, IF, IHC (p) 宿主: 小鼠 Monoclonal 6B12 unconjugated

应用备注

Western blot, 0.1-0.5 μg/mL, Human, Mouse, Rat Immunohistochemistry (Paraffin-embedded Section), 2-5 μg/mL, Human

说明

Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).

限制

仅限研究用
状态

Lyophilized

溶解方式

Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

浓度

500 μg/mL

缓冲液

Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.01 mg Sodium azide.

储存液

Sodium azide

注意事项

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

注意事项

Avoid repeated freezing and thawing.

储存条件

4 °C,-20 °C

储存方法

Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

有效期

12 months
Xu, Zhang, Wei, Jia, Ge, Zhang, Liu: "MicroRNA-21 promotes hepatocellular carcinoma HepG2 cell proliferation through repression of mitogen-activated protein kinase-kinase 3." in: BMC cancer, Vol. 13, pp. 469, (2013) (PubMed).
抗原

MAP2K3 (Mitogen-Activated Protein Kinase Kinase 3 (MAP2K3))

别名

MAP2K3

背景

Background: Dual specificity mitogen-activated protein kinase kinase 3 is an enzyme that in humans is encoded by the MAP2K3 gene. The protein encoded by this gene is a dual specificity protein kinase that belongs to the MAP kinase kinase family. This kinase is activated by mitogenic and environmental stress, and participates in the MAP kinase-mediated signaling cascade. It phosphorylates and thus activates MAPK14/p38-MAPK. This kinase can be activated by insulin, and is necessary for the expression of glucose transporter. Expression of RAS oncogene is found to result in the accumulation of the active form of this kinase, which thus leads to the constitutive activation of MAPK14, and confers oncogenic transformation of primary cells. Rampoldi et al. (1997) localized the MAP2K3 gene to 17q11.2.
Gene Full Name: mitogen-activated protein kinase kinase 3
Sequence Similarities: Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. MAP kinase kinase subfamily.

分子量

39 kDa

基因ID

5606

UniProt

P46734

途径

MAPK Pathway, TLR signaling, Activation of Innate immune Response, Toll-Like Receptors Cascades, Autophagy, Signaling Events mediated by VEGFR1 and VEGFR2