HLA-DMB 抗体 (Middle Region)
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- 抗原 See all HLA-DMB 抗体
- HLA-DMB (Major Histocompatibility Complex, Class II, DM beta (HLA-DMB))
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抗原表位
- AA 81-100, Middle Region
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This HLA-DMB antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- 原理
- Rabbit IgG polyclonal antibody for HLA class II histocompatibility antigen, DM beta chain(HLA-DMB) detection. Tested with WB, IHC-P in Human.
- 序列
- NQKDTLMQRL RNGLQNCATH
- 交叉反应 （详细）
- No cross reactivity with other proteins.
- 产品特性
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Rabbit IgG polyclonal antibody for HLA class II histocompatibility antigen, DM beta chain(HLA-DMB) detection. Tested with WB, IHC-P in Human.
Gene Name: major histocompatibility complex, class II, DM beta
Protein Name: HLA class II histocompatibility antigen, DM beta chain - 纯化方法
- Immunogen affinity purified.
- 免疫原
- A synthetic peptide corresponding to a sequence in the middle region of human HLA DMB(81-100aa NQKDTLMQRLRNGLQNCATH).
- 亚型
- IgG
- Top Product
- Discover our top product HLA-DMB Primary Antibody
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anti-Major Histocompatibility Complex, Class II, DM beta (HLA-DMB) (AA 22-129) antibody
HLA-DMB 适用: 人 WB, ELISA, IF, IP 宿主: 小鼠 Monoclonal 5G11 unconjugated
anti-Major Histocompatibility Complex, Class II, DM beta (HLA-DMB) (AA 40-100) antibodyHLA-DMB 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Major Histocompatibility Complex, Class II, DM beta (HLA-DMB) (AA 22-129) antibodyHLA-DMB 适用: 人 WB, ELISA, IP 宿主: 小鼠 Monoclonal 4D12 unconjugated
anti-Major Histocompatibility Complex, Class II, DM beta (HLA-DMB) antibodyHLA-DMB 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Major Histocompatibility Complex, Class II, DM beta (HLA-DMB) (AA 22-129) antibodyHLA-DMB 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 6B3 unconjugated
anti-Major Histocompatibility Complex, Class II, DM beta (HLA-DMB) (C-Term) antibodyHLA-DMB 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Major Histocompatibility Complex, Class II, DM beta (HLA-DMB) (AA 1-263) antibodyHLA-DMB 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Major Histocompatibility Complex, Class II, DM beta (HLA-DMB) (C-Term) antibodyHLA-DMB 适用: 人 WB, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Major Histocompatibility Complex, Class II, DM beta (HLA-DMB) antibodyHLA-DMB 适用: 人 WB 宿主: 兔 Monoclonal unconjugated
anti-Major Histocompatibility Complex, Class II, DM beta (HLA-DMB) (N-Term) antibodyHLA-DMB 适用: 人, 大鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
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- 应用备注
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WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human
IHC-P: Concentration: 0.5-1 μg/mL, Tested Species: Human, Epitope Retrieval by Heat: Boiling the paraffin sections in 10 mM citrate buffer, pH 6.0, for 20 mins is required for the staining of formalin/paraffin sections.
Notes: Tested Species: Species with positive results. Predicted Species: Species predicted to be fit for the product based on sequence similarities. Other applications have not been tested. Optimal dilutions should be determined by end users. - 说明
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Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).
- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
- 浓度
- 500 μg/mL
- 缓冲液
- Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg Sodium azide.
- 储存液
- Thimerosal (Merthiolate), Sodium azide
- 注意事项
- This product contains Sodium azide and Thimerosal (Merthiolate): POISONOUS AND HAZARDOUS SUBSTANCES which should be handled by trained staff only.
- 注意事项
- Avoid repeated freezing and thawing.
- 储存条件
- 4 °C/-20 °C
- 储存方法
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At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing. - 有效期
- 12 months
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- 抗原
- HLA-DMB (Major Histocompatibility Complex, Class II, DM beta (HLA-DMB))
- 别名
- HLA-DMB (HLA-DMB 产品)
- 别名
- RING7 antibody, D6S221E antibody, RT1.DMb antibody, RT1.Mb antibody, MHC-DMB antibody, major histocompatibility complex, class II, DM beta antibody, RT1 class II, locus DMb antibody, HLA-DMB antibody, RT1-DMb antibody, PATR-DMB antibody
- 背景
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HLA-DMB(major histocompatibility complex, class II, DM beta), also known as D6S221E, RING7, HLA-DM histocompatibility type, beta chain, HLADMB or RING7, is a protein that in humans is encoded by the HLA-DMB gene. The HLA-DMB gene is mapped on 6p21.32. HLA-DMB belongs to the HLA class II beta chain paralogues. This class II molecule is a heterodimer consisting of an alpha(DMA) and a beta(DMB) chain, both anchored in the membrane. It is located in intracellular vesicles. DM plays a central role in the peptide loading of MHC class II molecules by helping to release the CLIP(class II-associated invariant chain peptide) molecule from the peptide binding site. Class II molecules are expressed in antigen presenting cells. The beta chain is approximately 26-28 kDa and its gene contains 6 exons. HLA-DMA and -DMB appear to encode subunits of a functional heterodimer that is critical in the pathway of class II antigen presentation.
Synonyms: class II antigen HLA-DM beta chain antibody|class II histocompatibility antigen antibody|Class II histocompatibility antigen M beta chain antibody|D6S221E antibody|DMB antibody|HLA class II histocompatibility antigen DM beta chain antibody|HLA-DM histocompatibility type, beta chain antibody|M beta chain antibody|Major histocompatibility complex class II DM beta antibody|MHC class II antigen DMB antibody|MHC class II antigen HLA DM beta chain antibody|MHC class II HLA DMB antibody|OTTHUMP00000029257 antibody|Really interesting new gene 7 protein antibody|RING 7 antibody|RING7 antibody - UniProt
- P28068
- 途径
- Cancer Immune Checkpoints
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