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- 抗原 See all HLA-DMB 抗体
- HLA-DMB (Major Histocompatibility Complex, Class II, DM beta (HLA-DMB))
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抗原表位
- N-Term
- 适用
- 人, 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This HLA-DMB antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunohistochemistry (IHC)
- 序列
- FTYCISFNKD LLTCWDPEEN KMAPCEFGVL NSLANVLSQH LNQKDTLMQR
- 预测反应
- Human: 100%, Rat: 86%
- 产品特性
- This is a rabbit polyclonal antibody against HLA-DMB. It was validated on Western Blot.
- 纯化方法
- Affinity Purified
- Top Product
- Discover our top product HLA-DMB Primary Antibody
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anti-Major Histocompatibility Complex, Class II, DM beta (HLA-DMB) (AA 22-129) antibody
HLA-DMB 适用: 人 WB, ELISA, IF, IP 宿主: 小鼠 Monoclonal 5G11 unconjugated
anti-Major Histocompatibility Complex, Class II, DM beta (HLA-DMB) (AA 40-100) antibodyHLA-DMB 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Major Histocompatibility Complex, Class II, DM beta (HLA-DMB) (AA 22-129) antibodyHLA-DMB 适用: 人 WB, ELISA, IP 宿主: 小鼠 Monoclonal 4D12 unconjugated
anti-Major Histocompatibility Complex, Class II, DM beta (HLA-DMB) antibodyHLA-DMB 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Major Histocompatibility Complex, Class II, DM beta (HLA-DMB) (AA 22-129) antibodyHLA-DMB 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 6B3 unconjugated
anti-Major Histocompatibility Complex, Class II, DM beta (HLA-DMB) (C-Term) antibodyHLA-DMB 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Major Histocompatibility Complex, Class II, DM beta (HLA-DMB) (AA 81-100), (Middle Region) antibodyHLA-DMB 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Major Histocompatibility Complex, Class II, DM beta (HLA-DMB) (AA 1-263) antibodyHLA-DMB 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Major Histocompatibility Complex, Class II, DM beta (HLA-DMB) (C-Term) antibodyHLA-DMB 适用: 人 WB, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Major Histocompatibility Complex, Class II, DM beta (HLA-DMB) antibodyHLA-DMB 适用: 人 WB 宿主: 兔 Monoclonal unconjugated
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- 应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
- 说明
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Antigen size: 263 AA
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- Lot specific
- 缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freeze-thaw cycles.
- 储存条件
- -20 °C
- 储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- 抗原
- HLA-DMB (Major Histocompatibility Complex, Class II, DM beta (HLA-DMB))
- 别名
- HLA-DMB (HLA-DMB 产品)
- 别名
- RING7 antibody, D6S221E antibody, RT1.DMb antibody, RT1.Mb antibody, MHC-DMB antibody, major histocompatibility complex, class II, DM beta antibody, RT1 class II, locus DMb antibody, HLA-DMB antibody, RT1-DMb antibody, PATR-DMB antibody
- 背景
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HLA-DMB belongs to the HLA class II beta chain paralogues. This class II molecule is a heterodimer consisting of an alpha (DMA) and a beta (DMB) chain, both anchored in the membrane. It is located in intracellular vesicles. DM plays a central role in the peptide loading of MHC class II molecules by helping to release the CLIP (class II-associated invariant chain peptide) molecule from the peptide binding site. Class II molecules are expressed in antigen presenting cells (APC: B lymphocytes, dendritic cells, macrophages). The beta chain is approximately 26-28 kDa and its gene contains 6 exons. Exon one encodes the leader peptide, exons 2 and 3 encode the two extracellular domains, exon 4 encodes the transmembrane domain and exon 5 encodes the cytoplasmic tail.
Alias Symbols: D6S221E, RING7
Protein Interaction Partner: CUL3, TEAD1, MDM2, DPM2, CD82, HLA-DOB, CD63, HLA-DRA, HLA-DMA, CD74,
Protein Size: 263 - 分子量
- 29 kDa
- 基因ID
- 3109
- NCBI登录号
- NM_002118, NP_002109
- UniProt
- P28068
- 途径
- Cancer Immune Checkpoints
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