MAP2K3 抗体 (C-Term)
(2 references)-
- 抗原 See all MAP2K3 抗体
- MAP2K3 (Mitogen-Activated Protein Kinase Kinase 3 (MAP2K3))
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抗原表位
- AA 311-347, C-Term
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适用
- 人, 小鼠, 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This MAP2K3 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC), Flow Cytometry (FACS)
- 原理
- Anti-MEK3/MAP2K3 Antibody Picoband®
- 序列
- AERMSYLELM EHPFFTLHKT KKTDIAAFVK EILGEDS
- 交叉反应 （详细）
- No cross-reactivity with other proteins.
- 产品特性
- Anti-MEK3/MAP2K3 Antibody Picoband® (ABIN3043874). Tested in Flow Cytometry, IF, IHC, ICC, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
- 纯化方法
- Immunogen affinity purified.
- 免疫原
- A synthetic peptide corresponding to a sequence at the C-terminus of human MEK3, identical to the related mouse sequence.
- 亚型
- IgG
- Top Product
- Discover our top product MAP2K3 Primary Antibody
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anti-Mitogen-Activated Protein Kinase Kinase 3 (MAP2K3) (AA 1-170) antibody
MAP2K3 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Mitogen-Activated Protein Kinase Kinase 3 (MAP2K3) antibodyMAP2K3 适用: 人, 犬, 猴 WB, IHC, IF, IHC (p) 宿主: 小鼠 Monoclonal 5C7 unconjugated
anti-Mitogen-Activated Protein Kinase Kinase 3 (MAP2K3) antibodyMAP2K3 适用: 人, 小鼠, 犬, 猴 WB, IHC, IF, IHC (p) 宿主: 小鼠 Monoclonal 5D3 unconjugated
anti-Mitogen-Activated Protein Kinase Kinase 3 (MAP2K3) (AA 1-138) antibodyMAP2K3 适用: 人 IHC, ELISA, ICC, FACS 宿主: 小鼠 Monoclonal 2E12D11 unconjugated
anti-Mitogen-Activated Protein Kinase Kinase 3 (MAP2K3) (AA 1-100) antibodyMAP2K3 适用: 人 WB, ELISA, IHC (p), IP 宿主: 小鼠 Monoclonal 1D10 unconjugated
anti-Mitogen-Activated Protein Kinase Kinase 3 (MAP2K3) antibodyMAP2K3 适用: 人, 小鼠, 大鼠, 犬, 猴 WB, IHC, IF, IHC (p) 宿主: 小鼠 Monoclonal 5F2 unconjugated
anti-Mitogen-Activated Protein Kinase Kinase 3 (MAP2K3) (pSer189) antibodyMAP2K3 适用: 人 WB, IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Mitogen-Activated Protein Kinase Kinase 3 (MAP2K3) (AA 15-45), (N-Term) antibodyMAP2K3 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal RB0928 unconjugated
anti-Mitogen-Activated Protein Kinase Kinase 3 (MAP2K3) (pSer189) antibodyMAP2K3 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Mitogen-Activated Protein Kinase Kinase 3 (MAP2K3) antibodyMAP2K3 适用: 人, 小鼠, 大鼠, 犬, 猴 WB, IHC, IF, IHC (p) 宿主: 小鼠 Monoclonal 1B5 unconjugated
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- 应用备注
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Western blot, 0.25-0.5 μg/mL, Human, Mouse, Rat
Immunohistochemistry (Paraffin-embedded Section), 2-5 μg/mL, Human
Immunocytochemistry/Immunofluorescence, 5 μg/mL, Human
Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human
1. Rampoldi L, Zimbello R, Bortoluzzi S, Tiso N, Valle G, Lanfranchi G, Danieli GA (Mar 1998). "Chromosomal localization of four MAPK signaling cascade genes: MEK1, MEK3, MEK4 and MEKK5". Cytogenet Cell Genet 78 (3-4): 301-3. - 说明
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Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).
- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
- 浓度
- 500 μg/mL
- 缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl and 0.2 mg Na2HPO4.
- 注意事项
- Avoid repeated freezing and thawing.
- 储存条件
- 4 °C,-20 °C
- 储存方法
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Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
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: "Silencing Ras-Related C3 Botulinum Toxin Substrate 1 Inhibits Growth and Migration of Hypopharyngeal Squamous Cell Carcinoma via the P38 Mitogen-Activated Protein Kinase Signaling Pathway." in: Medical science monitor : international medical journal of experimental and clinical research, Vol. 24, pp. 768-781, (2018) (PubMed).
: "MicroRNA-21 promotes hepatocellular carcinoma HepG2 cell proliferation through repression of mitogen-activated protein kinase-kinase 3." in: BMC cancer, Vol. 13, pp. 469, (2013) (PubMed).
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: "Silencing Ras-Related C3 Botulinum Toxin Substrate 1 Inhibits Growth and Migration of Hypopharyngeal Squamous Cell Carcinoma via the P38 Mitogen-Activated Protein Kinase Signaling Pathway." in: Medical science monitor : international medical journal of experimental and clinical research, Vol. 24, pp. 768-781, (2018) (PubMed).
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- 抗原
- MAP2K3 (Mitogen-Activated Protein Kinase Kinase 3 (MAP2K3))
- 别名
- MAP2K3 (MAP2K3 产品)
- 背景
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Synonyms: Dual specificity mitogen-activated protein kinase kinase 3,MAP kinase kinase 3,MAPKK 3,2.7.12.2,MAPK/ERK kinase 3,MEK 3,Stress-activated protein kinase kinase 2,SAPK kinase 2,SAPKK-2,SAPKK2,MAP2K3,MEK3, MKK3, PRKMK3, SKK2,
Tissue Specificity: Abundant expression is seen in the skeletal muscle. It is also widely expressed in other tissues.
Background: Dual specificity mitogen-activated protein kinase kinase 3 is an enzyme that in humans is encoded by the MAP2K3 gene. The protein encoded by this gene is a dual specificity protein kinase that belongs to the MAP kinase kinase family. This kinase is activated by mitogenic and environmental stress, and participates in the MAP kinase-mediated signaling cascade. It phosphorylates and thus activates MAPK14/p38-MAPK. And this kinase can be activated by insulin, and is necessary for the expression of glucose transporter. Expression of RAS oncogene is found to result in the accumulation of the active form of this kinase, which thus leads to the constitutive activation of MAPK14, and confers oncogenic transformation of primary cells. Rampoldi et al. (1997) localized the MAP2K3 gene to 17q11.2.
- 分子量
- 40 kDa
- 基因ID
- 5606
- UniProt
- P46734
- 途径
- MAPK Pathway, TLR signaling, Activation of Innate immune Response, Toll-Like Receptors Cascades, Autophagy, Signaling Events mediated by VEGFR1 and VEGFR2
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