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CD40 抗体 (N-Term)

Name: CD40 抗体 (N-Term)
SKU: ABIN3043683
Availability: OutOfStock

CD40 适用: 小鼠 WB 宿主: 兔 Polyclonal unconjugated

Anti-CD40 antibody, Western blotting Lane 1: Recombinant Mouse CD 40 Protein 10ng Lane 2: Recombinant Mouse CD 40 Protein 5ng Lane 3: Recombinant Mouse CD 40 Protein 2. (CD40 抗体 (N-Term))

Anti-CD40 antibody, Western blotting Lane 1: Recombinant Human CD40 Protein 10ng Lane 2: Recombinant Human CD40 Protein 5ng Lane 3: Recombinant Human CD40 Protein 2. (CD40 抗体 (N-Term))

2 images

(2 references)

产品编号 ABIN3043683

发货至: 中国

Datasheet as PDF

抗原 See all CD40 抗体

CD40
抗原表位
17

16

14

13

13

12

9

5

5

4

3

3

2

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1
AA 22-36, N-Term
适用
188

97

20

20

7

6

4

4

4

4

2

2

2

2

2

1

1
小鼠
宿主
103

100

43

3

1

1

1
兔
Compatible Secondaries
克隆类型
156

89

5
多克隆
标记
119

22

20

20

12

6

5

4

3

3

3

3

3

3

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1
This CD40 antibody is un-conjugated
应用范围
145

92

62

50

30

28

19

18

17

14

13

13

5

4

4

4

3

3

3

3

3

2

2

2

2

2

1

1
Western Blotting (WB)

原理

Rabbit IgG polyclonal antibody for Tumor necrosis factor receptor superfamily member 5(CD40) detection. Tested with WB in Mouse.

序列

QCVTCSDKQY LHDGQ

交叉反应（详细）

No cross reactivity with other proteins.

产品特性

Rabbit IgG polyclonal antibody for Tumor necrosis factor receptor superfamily member 5(CD40) detection. Tested with WB in Mouse.
Gene Name: CD40 Molecule, TNF receptor superfamily member 5
Protein Name: Tumor necrosis factor receptor superfamily member 5

纯化方法

Immunogen affinity purified.

免疫原

A synthetic peptide corresponding to a sequence at the N-terminus of mouse CD40(22-36aa, QCVTCSDKQYLHDGQ).

亚型

IgG

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CD40 适用: 人 FACS 宿主: 小鼠 Monoclonal HI40a FITC

应用备注

WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Mouse
Notes: Tested Species: Species with positive results. Predicted Species: Species predicted to be fit for the product based on sequence similarities.
Other applications have not been tested. Optimal dilutions should be determined by end users.

说明

Antibody can be supported by chemiluminescence kit ABIN921124 in WB.

限制

仅限研究用
状态

Lyophilized

溶解方式

Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

浓度

500 μg/mL

缓冲液

Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg Sodium azide.

储存液

Thimerosal (Merthiolate), Sodium azide

注意事项

This product contains Sodium azide and Thimerosal (Merthiolate): POISONOUS AND HAZARDOUS SUBSTANCES which should be handled by trained staff only.

注意事项

Avoid repeated freezing and thawing.

储存条件

4 °C/-20 °C

储存方法

At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.

有效期

12 months
Meng, Li, Geng, Ohe, Yu, E, Ye, Yang, Kato, Zhang, Ishida, Ohta, Jin, Kakehata, Geng, Yamakawa: "Decreased expression of follicular dendritic cell-secreted protein correlates with increased immunoglobulin A production in the tonsils of individuals with immunoglobulin A nephropathy." in: Translational research : the journal of laboratory and clinical medicine, Vol. 166, Issue 3, pp. 281-91, (2015) (PubMed).

Peng, Cheng, Zeng, Shi, Bao, Mao, Ji, Li, Guo, Liang, Wu: "The role of RANTES as a crucial downstream cytokine in calcineurin-dependent VSMC apoptosis stimulated by INFgamma and CD40L." in: Cell biology international, Vol. 34, Issue 5, pp. 447-53, (2010) (PubMed).
抗原

CD40

别名

CD40 (CD40 产品)

别名

Bp50 antibody, CDW40 antibody, TNFRSF5 antibody, p50 antibody, AI326936 antibody, GP39 antibody, HIGM1 antibody, IGM antibody, IMD3 antibody, T-BAM antibody, TRAP antibody, Tnfrsf5 antibody, TNFSF5 antibody, CD40 molecule antibody, CD40 antigen antibody, CD40 antibody, Cd40 antibody

背景

CD40 is a cell surface receptor that is expressed on the surface of all mature B cells and also expressed on monocytes, dendritic cells, and thymic epithelium. CD40 is a member of the tumor necrosis factor(TNF) receptor superfamily and is the receptor for CD40 ligand. CD40 ligand(CD40L, CD154, gp39, and TRAM) belongs to the TNF gene family and is expressed more widely than CD40 predominantly on activated CD4+ T cells. Activation of CD40 has also been shown to inhibit the growth of certain B cell lymphomas and to induce the death of transformed cells of mesenchymal or epithelial origin.

Synonyms: AI326936 antibody|B cell associated molecule CD40 antibody|B cell surface antigen CD40 antibody|B cell-associated molecule antibody|B-cell surface antigen CD40 antibody|Bp50 antibody|CD 40 antibody|CD40 antibody|CD40 antigen(TNF receptor superfamily member 5) antibody|CD40 antigen antibody|CD40 Molecule antibody|CD40 Molecule, TNF receptor superfamily member 5 antibody|CD40 protein antibody|CD40 type II isoform antibody|CD40L receptor antibody|CDw40 antibody|GP39 antibody|HIGM1 antibody|IGM antibody|IMD3 antibody|MGC9013 antibody|Nerve growth factor receptor related B lymphocyte activation molecule antibody|OTTHUMP00000031699 antibody|OTTHUMP00000031700 antibody|p50 antibody|T-BAM antibody|TBAM antibody|TNF receptor superfamily member 5 antibody|TNFRSF5 antibody|TNR5_HUMAN antibody|TRAP antibody|Tumor necrosis factor receptor superfamily , member 5 antibody|Tumor necrosis factor receptor superfamily member 5 antibody|Tumor necrosis factor receptor superfamily member 5 precursor antibody|Tumor necrosis factor receptor superfamily, member 5, isoform CRA_a antibody

UniProt

P27512

途径

NF-kappaB Signaling, Cellular Response to Molecule of Bacterial Origin, M Phase, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Cancer Immune Checkpoints